Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | KLK7 | P49862 | 1/20 | 0.45 |
| ▸ | AR | P10275 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10014726 | 0.92 | KMT2A (0.54) | LMNATP53MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL10014727 | 0.88 | MEN1 (0.50) | LMNATP53MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL11508035 | 0.80 | LMNA (0.55) | LMNATP53MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL17637037 | 0.79 | KMT2A (0.61) | LMNATP53MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL17637042 | 0.78 | NPSR1 (0.55) | LMNAMEN1KMT2AHTTALDH1A1 | |
| SCHEMBL17637038 | 0.76 | POLB (0.40) | LMNAMEN1KMT2ASMN1; SMN2GAA | |
| SCHEMBL13863485 | 0.75 | AR (0.48) | LMNAMEN1KMT2ASMN1; SMN2GAA | |
| SCHEMBL11180860 | 0.75 | CYP19A1 (0.42) | LMNAMEN1KMT2AHTTALDH1A1 | |
| SCHEMBL13135883 | 0.73 | MAPT (0.48) | LMNATP53KMT2ASMN1; SMN2GAA | |
| SCHEMBL6934183 | 0.72 | AR (0.70) | MEN1KMT2ASMN1; SMN2GAAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8349942-B2 | Intermediate transfer member | XEROX CORPORATION (US) | 2013-01-08 | — | — | US | disclosed |