SCHEMBL10014784

SCHEMBL10014784

O=P(Oc1ccc2c(c1)CN(c1cccnc1)CN2)(Oc1ccc2c(c1)CN(c1cccnc1)CO2)c1ccccc1

nearest known ligand 0.31

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 1/20 0.31
CYP2D6 P10635 1/20 0.31
HIF1A Q16665 1/20 0.31
TDP1 Q9NUW8 1/20 0.30
L3MBTL1 Q9Y468 1/20 0.30
CHRNB2 P17787 1/20 0.30
CHRNA4 P43681 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10014798 0.92 TDP1 (0.35) CYP3A4CYP2D6HIF1ATDP1L3MBTL1
SCHEMBL12170271 0.90 GRM5 (0.32) CYP3A4CYP2D6HIF1ACHRNB2CHRNA4
SCHEMBL13912134 0.77
SCHEMBL10014785 0.73
SCHEMBL10014789 0.72 CYP3A4 (0.41) CYP3A4CYP2D6HIF1ATDP1
SCHEMBL10311140 0.71 CYP3A4 (0.40) CYP3A4CYP2D6HIF1ATDP1L3MBTL1
SCHEMBL17460732 0.69 GAA (0.31)
SCHEMBL13445261 0.69 NPC1 (0.33)
SCHEMBL765444 0.68 CYP11B2 (0.42) CHRNB2CHRNA4
SCHEMBL10045015 0.66 CHRNB2 (0.42) CHRNB2CHRNA4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9243012-B2 Phosphorous containing benzoxazine-based monomer, or polymer thereof SAMSUNG ELECTRONICS CO., LTD. (KR) 2016-01-26 US disclosed
US-9243012-B2 Phosphorous containing benzoxazine-based monomer, or polymer thereof SAMSUNG ELECTRONICS CO., LTD. (KR) 2016-01-26 US disclosed
US-20120264909-A1 PHOSPHOROUS CONTAINING BENZOXAZINE-BASED MONOMER, POLYMER THEREOF, ELECTRODE FOR FUEL CELL INCLUDING THE SAME, ELECTROLYTE MEMBRANE FOR FUEL CELL INCLUDING THE SAME, AND FUEL CELL EMPLOYING THE SAME SAMSUNG ELECTRONICS CO., LTD. (KR) 2012-10-18 US disclosed
US-20120264909-A1 PHOSPHOROUS CONTAINING BENZOXAZINE-BASED MONOMER, POLYMER THEREOF, ELECTRODE FOR FUEL CELL INCLUDING THE SAME, ELECTROLYTE MEMBRANE FOR FUEL CELL INCLUDING THE SAME, AND FUEL CELL EMPLOYING THE SAME SAMSUNG ELECTRONICS CO., LTD. (KR) 2012-10-18 US disclosed
EP-2036912-B1 Phosphorous containing benzoxazine-based monomer, polymer thererof, electrode for fuel cell including the same, electrolyte membrane for fuel cell including the same, and fuel cell employing the same SAMSUNG ELECTRONICS CO LTD (KR) 2012-08-08 EP disclosed
US-8192892-B2 Phosphorous containing benzoxazine-based monomer, polymer thereof, electrode for fuel cell including the same, electrolyte membrane for fuel cell including the same, and fuel cell employing the same SAMSUNG ELECTRONICS CO., LTD. (KR) 2012-06-05 US disclosed
US-20090068543-A1 PHOSPHOROUS CONTAINING BENZOXAZINE-BASED MONOMER, POLYMER THEREROF, ELECTRODE FOR FUEL CELL INCLUDING THE SAME, ELECTROLYTE MEMBRANE FOR FUEL CELL INCLUDING THE SAME, AND FUEL CELL EMPLOYING THE SAME SAMSUNG ELECTRONICS CO., LTD. (KR) 2009-03-12 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120264909-A1 PHOSPHOROUS CONTAINING BENZOXAZINE-BASED MONOMER, POLYMER THEREOF, ELECTRODE FOR FUEL CELL INCLUDING THE SAME, ELECTROLYTE MEMBRANE FOR FUEL CELL INCLUDING THE SAME, AND FUEL CELL EMPLOYING THE SAME PDK2, PCK1, PDK4 CYP3A4 1526/4885CYP2D6 3231/4885HIF1A 2698/4885
US-20090068543-A1 PHOSPHOROUS CONTAINING BENZOXAZINE-BASED MONOMER, POLYMER THEREROF, ELECTRODE FOR FUEL CELL INCLUDING THE SAME, ELECTROLYTE MEMBRANE FOR FUEL CELL INCLUDING THE SAME, AND FUEL CELL EMPLOYING THE SAME WEE1, HADHB, PXMP4 CYP3A4 835/4885CYP2D6 2499/4885HIF1A 3283/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.