Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 9/20 | 0.60 |
| ▸ | FAAH | O00519 | 5/20 | 0.60 |
| ▸ | PTGS1 | P23219 | 7/20 | 0.58 |
| ▸ | PTGS2 | P35354 | 7/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.58 |
| ▸ | LMNA | P02545 | 2/20 | 0.58 |
| ▸ | MAPT | P10636 | 2/20 | 0.58 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.58 |
| ▸ | HPGD | P15428 | 2/20 | 0.58 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.58 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.58 |
| ▸ | TP53 | P04637 | 1/20 | 0.58 |
| ▸ | PKM | P14618 | 1/20 | 0.58 |
| ▸ | XBP1 | P17861 | 1/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.58 |
| ▸ | HTT | P42858 | 1/20 | 0.58 |
| ▸ | RECQL | P46063 | 1/20 | 0.58 |
| ▸ | RAB9A | P51151 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.58 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14524212 | 0.94 | PTGS1 (0.67) | MGLLFAAHPTGS1PTGS2ALDH1A1 | |
| SCHEMBL22237613 | 0.92 | PTGS1 (0.70) | MGLLFAAHPTGS1PTGS2ALDH1A1 | |
| SCHEMBL14968624 | 0.92 | PTGS1 (0.70) | MGLLFAAHPTGS1PTGS2ALDH1A1 | |
| SCHEMBL10173306 | 0.92 | PTGS1 (0.70) | MGLLFAAHPTGS1PTGS2ALDH1A1 | |
| SCHEMBL24637632 | 0.92 | PTGS1 (0.70) | MGLLFAAHPTGS1PTGS2ALDH1A1 | |
| SCHEMBL2734915 | 0.87 | MGLL (0.52) | MGLLFAAHPTGS1PTGS2ALDH1A1 | |
| SCHEMBL17453155 | 0.82 | PTGS1 (0.49) | MGLLFAAHPTGS1PTGS2ALDH1A1 | |
| SCHEMBL25147949 | 0.82 | MGLL (0.58) | MGLLFAAHPTGS1PTGS2ALDH1A1 | |
| SCHEMBL1965501 | 0.81 | MGLL (0.62) | MGLLFAAHPTGS1PTGS2ALDH1A1 | |
| SCHEMBL155346 | 0.81 | PTGS1 (0.85) | MGLLFAAHPTGS1PTGS2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 119 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11860167-B2 | Application of click chemistry for signal amplification in IHC and ISH assays | VENTANA MEDICAL SYSTEMS, INC. (US) | 2024-01-02 | — | — | US | disclosed |
| US-11833219-B2 | Method for producing antibody-drug conjugate intermediate by addition of acid and use thereof | MABPLEX INTERNATIONAL CO., LTD. (CN) | 2023-12-05 | — | — | US | disclosed |
| US-20230158141-A1 | Conjugates of Biomolecule and Use Thereof | YAFEI SHANGHAI BIOLOG MEDICINE SCIENCE & TECHNOLOG (CN) | 2023-05-25 | — | — | US | disclosed |
| WO-2023061405-A1 | HIGHLY-STABLE TARGETED LINKER-DRUG CONJUGATE | 成都科岭源医药技术有限公司 | 2023-04-20 | — | — | WO | disclosed |
| US-20230115871-A1 | A CONJUGATE OF A CYTOTOXIC AGENT TO A CELL BINDING MOLECULE WITH BRANCHED LINKERS | HANGZHOU DAC BIOTECH CO., LTD (CN) | 2023-04-13 | — | — | US | disclosed |
| US-11564971-B2 | Hyaluronic acid derivative having amino acid and steryl group introduced thereinto | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2023-01-31 | — | — | US | disclosed |
| WO-2022160156-A1 | LIGASE FUSION PROTEINS AND APPLICATIONS THEREOF | GENEQUANTUM HEALTHCARE (SUZHOU) CO., LTD. (CN) | 2022-08-04 | — | — | WO | disclosed |
| EP-3838913-A1 | OLIGOPEPTIDE LINKER INTERMEDIATE AND PREPARATION METHOD THEREFOR | MabPlex International Co., Ltd. (CN) | 2021-06-23 | — | — | EP | disclosed |
| WO-2021077317-A1 | OLIGOPEPTIDE LINKER INTERMEDIATE AND PREPARATION METHOD THEREFOR | 烟台迈百瑞国际生物医药股份有限公司 | 2021-04-29 | — | — | WO | disclosed |
| US-20200276261-A1 | A CONJUGATE OF A TUBULYSIN ANALOG WITH BRANCHED LINKERS | HANGZHOU DAC BIOTECH CO., LTD. (CN) | 2020-09-03 | — | — | US | disclosed |
| WO-2009073533-A2 | ANTI-B7H4 MONOCLONAL ANTIBODY-DRUG CONJUGATE AND METHODS OF USE | MEDAREX, INC. (US) | 2009-06-11 | — | — | WO | disclosed |
| WO-2009073524-A2 | CONJUGATES OF ANTI-RG-1 ANTIBODIES | MEDAREX, INC. (US) | 2009-06-11 | — | — | WO | disclosed |
| WO-2009045957-A1 | HUMAN ANTIBODIES THAT BIND MESOTHELIN, AND USES THEREOF | MEDAREX, INC. (US) | 2009-04-09 | — | — | WO | disclosed |
| WO-2009026274-A1 | SITE-SPECIFIC ATTACHMENT OF DRUGS OR OTHER AGENTS TO ENGINEERED ANTIBODIES WITH C-TERMINAL EXTENSIONS | MEDAREX, INC. (US) | 2009-02-26 | — | — | WO | disclosed |
| WO-2008103693-A2 | CHEMICAL LINKERS WITH SINGLE AMINO ACIDS AND CONJUGATES THEREOF | MEDAREX, INC. (US) | 2008-08-28 | — | — | WO | disclosed |
| WO-2008083312-A2 | CHEMICAL LINKERS AND CLEAVABLE SUBSTRATES AND CONJUGATES THEREOF | MEDAREX, INC. (US) | 2008-07-10 | — | — | WO | disclosed |
| WO-2008074004-A2 | HUMAN ANTIBODIES THAT BIND CD70 AND USES THEREOF | MEDAREX, INC. (US) | 2008-06-19 | — | — | WO | disclosed |
| WO-2008070569-A2 | HUMAN ANTIBODIES THAT BIND CD22 AND USES THEREOF | MEDAREX, INC. (US) | 2008-06-12 | — | — | WO | disclosed |
| US-20080139459-A1 | Conjugates A Polypeptide And A Pentasaccharide | N.V. ORGANON (NL) | 2008-06-12 | — | — | US | disclosed |
| US-20080071068-A1 | Cytoplasmic Localization Dna and Rna | NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY (JP) | 2008-03-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11833219-B2 | Method for producing antibody-drug conjugate intermediate by addition of acid and use thereof | AURKA, AURKC, CA14 | MGLL 4212/4885FAAH 4585/4885PTGS1 4440/4885 |
| US-20080139459-A1 | Conjugates A Polypeptide And A Pentasaccharide | SERPINC1, F13A1, F13B | MGLL 4446/4885FAAH 3219/4885PTGS1 3692/4885 |
| US-11860167-B2 | Application of click chemistry for signal amplification in IHC and ISH assays | MKI67, TIE1, ALK | MGLL 4641/4885FAAH 1938/4885PTGS1 1640/4885 |
| US-20230158141-A1 | Conjugates of Biomolecule and Use Thereof | CD47, FCGR2A, CD40 | MGLL 2474/4885FAAH 2216/4885PTGS1 1461/4885 |
| US-20230115871-A1 | A CONJUGATE OF A CYTOTOXIC AGENT TO A CELL BINDING MOLECULE WITH BRANCHED LINKERS | CD2BP2, EPCAM, CD74 | MGLL 4288/4885FAAH 4161/4885PTGS1 4228/4885 |
| US-20200276261-A1 | A CONJUGATE OF A TUBULYSIN ANALOG WITH BRANCHED LINKERS | TEKT1, TEK, BTN3A1 | MGLL 4616/4885FAAH 4519/4885PTGS1 4362/4885 |
| US-11564971-B2 | Hyaluronic acid derivative having amino acid and steryl group introduced thereinto | CD44, DAO, FUT6 | MGLL 3283/4885FAAH 2169/4885PTGS1 1245/4885 |
| US-20080071068-A1 | Cytoplasmic Localization Dna and Rna | HNRNPH3, HNRNPUL2, HNRNPUL1 | MGLL 4553/4885FAAH 4594/4885PTGS1 4748/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.