Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA9 | Q16790 | 8/20 | 0.43 |
| ▸ | CA1 | P00915 | 7/20 | 0.43 |
| ▸ | CA2 | P00918 | 7/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.43 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.42 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | FAAH | O00519 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | STAT1 | P42224 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11921504 | 0.85 | LMNA (0.42) | KDM4CMAPTLMNAPOLBGAA | |
| SCHEMBL27795106 | 0.83 | LMNA (0.49) | KDM4CMAPTLMNAGAAKMT2A | |
| SCHEMBL12713151 | 0.81 | ALDH1A1 (0.38) | CA9CA1CA2PTGS2KDM4C | |
| SCHEMBL27816073 | 0.77 | MAPK1 (0.51) | KDM4CMAPTLMNAPOLBGAA | |
| SCHEMBL27816078 | 0.76 | ALDH1A1 (0.49) | MAPTLMNAGAAKMT2AL3MBTL1 | |
| SCHEMBL27816070 | 0.75 | GAA (0.54) | KDM4CMAPTLMNAGAAKMT2A | |
| SCHEMBL2841874 | 0.72 | GAA (0.49) | CA9CA1CA2PTGS2KDM4C | |
| SCHEMBL13861488 | 0.71 | CYP1A2 (0.56) | CA9CA1CA2PTGS2P2RX7 | |
| SCHEMBL16804455 | 0.71 | MAPT (0.63) | CA9CA1CA2PTGS2P2RX7 | |
| SCHEMBL17361370 | 0.71 | PTGS2 (0.49) | CA9CA1CA2PTGS2P2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9029577-B2 | Method for producing methylene-1,3-dioxolanes | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2015-05-12 | — | — | US | disclosed |
| US-20140378690-A1 | METHOD FOR PRODUCING METHYLENE-1,3-DIOXOLANES | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2014-12-25 | — | — | US | disclosed |
| US-20130018192-A1 | Aryl-substituted Pyrazoles | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2013-01-17 | — | — | US | disclosed |
| US-8299260-B2 | Process for preparing aryl-substituted pyrazoles | BAYER CROPSCIENCE AG (DE) | 2012-10-30 | — | — | US | disclosed |
| US-8222435-B2 | Dioxolane and dioxane derivatives and a process for their preparation | BAYER CROPSCIENCE AG (DE) | 2012-07-17 | — | — | US | disclosed |
| US-20120022285-A1 | Novel alkoxy enones and enamino ketones and a process for preparation thereof | BAYER CROPSCIENCE AG (DE) | 2012-01-26 | — | — | US | disclosed |
| US-20110152531-A1 | Novel Dioxolane And Dioxane Derivatives And A Process For Their Preparation | BAYER CROPSCIENCE AG (DE) | 2011-06-23 | — | — | US | disclosed |
| US-20110028729-A1 | Process for preparing aryl-substituted pyrazoles | BAYER CROPSCIENCE AG (DE) | 2011-02-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130018192-A1 | Aryl-substituted Pyrazoles | WNK3, AHR, TYR | CA9 4733/4885CA1 4624/4885CA2 4763/4885 |
| US-20120022285-A1 | Novel alkoxy enones and enamino ketones and a process for preparation thereof | AKR7A2, CYP51A1, PDK3 | CA9 4062/4885CA1 3620/4885CA2 3289/4885 |
| US-20140378690-A1 | METHOD FOR PRODUCING METHYLENE-1,3-DIOXOLANES | CYP4X1, CYP1A1, DDT | CA9 2461/4885CA1 999/4885CA2 3144/4885 |
| US-20110028729-A1 | Process for preparing aryl-substituted pyrazoles | WNK3, WNK2, TYR | CA9 4674/4885CA1 4661/4885CA2 4813/4885 |
| US-20110152531-A1 | Novel Dioxolane And Dioxane Derivatives And A Process For Their Preparation | ACOX1, CYP4X1, ANTXR2 | CA9 2629/4885CA1 1523/4885CA2 2207/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.