Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 2/20 | 0.43 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.43 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.43 |
| ▸ | CHRNA1 | P02708 | 1/20 | 0.36 |
| ▸ | CHRNG | P07510 | 1/20 | 0.36 |
| ▸ | CHRNB1 | P11230 | 1/20 | 0.36 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.36 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.36 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.36 |
| ▸ | CHRND | Q07001 | 1/20 | 0.36 |
| ▸ | FYN | P06241 | 1/20 | 0.35 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.31 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.31 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12976250 | 0.91 | OPRM1 (0.43) | OPRM1OPRK1OPRL1CHRNA1CHRNG | |
| SCHEMBL2885461 | 0.91 | OPRM1 (0.43) | OPRM1OPRK1OPRL1CHRNA1CHRNG | |
| SCHEMBL7859980 | 0.89 | OPRM1 (0.36) | OPRM1OPRK1OPRL1CHRNA1CHRNG | |
| SCHEMBL9346754 | 0.88 | OPRM1 (0.38) | OPRM1OPRK1OPRL1CHRNA1CHRNG | |
| SCHEMBL9346757 | 0.88 | OPRM1 (0.38) | OPRM1OPRK1OPRL1CHRNA1CHRNG | |
| SCHEMBL2856214 | 0.85 | OPRL1 (0.54) | OPRM1OPRK1OPRL1CHRNA1CHRNB1 | |
| SCHEMBL28514809 | 0.81 | OPRM1 (0.37) | OPRM1OPRK1OPRL1 | |
| SCHEMBL9346748 | 0.79 | OPRM1 (0.34) | OPRM1OPRK1OPRL1LMNAMAPT | |
| SCHEMBL10014989 | 0.78 | OPRM1 (0.39) | OPRM1OPRK1OPRL1FYNCYP2C9 | |
| SCHEMBL9827270 | 0.78 | OPRM1 (0.47) | OPRM1OPRK1OPRL1CHRNA1CHRNG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160326434-A1 | LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY INCLUDING THE SAME | SAMSUNG DISPLAY CO., LTD. (KR) | 2016-11-10 | — | — | US | disclosed |
| US-20160326434-A1 | LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY INCLUDING THE SAME | SAMSUNG DISPLAY CO., LTD. (KR) | 2016-11-10 | — | — | US | disclosed |
| CN-103717563-B | There is the compound of 2-fluorophenyl oxygen methylmethane structure | DIC CORP. (JP) | 2015-09-16 | — | — | CN | disclosed |
| US-9079836-B2 | Compound having 2-fluorophenyloxymethane structure, a method for preparing the same, a liquid crystal composition and a liquid crystal device | DIC CORPORATION (JP) | 2015-07-14 | — | — | US | disclosed |
| US-9079836-B2 | Compound having 2-fluorophenyloxymethane structure, a method for preparing the same, a liquid crystal composition and a liquid crystal device | DIC CORPORATION (JP) | 2015-07-14 | — | — | US | disclosed |
| US-8916718-B2 | Compound having 2-fluorophenyloxymethane structure | DIC CORPORATION (JP) | 2014-12-23 | — | — | US | disclosed |
| US-8916718-B2 | Compound having 2-fluorophenyloxymethane structure | DIC CORPORATION (JP) | 2014-12-23 | — | — | US | disclosed |
| US-20140330045-A1 | COMPOUND HAVING 2-FLUOROPHENYLOXYMETHANE STRUCTURE | DIC CORPORATION (JP) | 2014-11-06 | — | — | US | disclosed |
| US-20140330045-A1 | COMPOUND HAVING 2-FLUOROPHENYLOXYMETHANE STRUCTURE | DIC CORPORATION (JP) | 2014-11-06 | — | — | US | disclosed |
| US-20140275577-A1 | COMPOUND HAVING 2-FLUOROPHENYLOXYMETHANE STRUCTURE | DIC CORPORATION (JP) | 2014-09-18 | — | — | US | disclosed |
| US-20140275577-A1 | COMPOUND HAVING 2-FLUOROPHENYLOXYMETHANE STRUCTURE | DIC CORPORATION (JP) | 2014-09-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140330045-A1 | COMPOUND HAVING 2-FLUOROPHENYLOXYMETHANE STRUCTURE | INF2, CFL1, CFD | OPRM1 1682/4885OPRK1 3075/4885OPRL1 2434/4885 |
| US-20140275577-A1 | COMPOUND HAVING 2-FLUOROPHENYLOXYMETHANE STRUCTURE | PIK3CD, TEC, PIK3C3 | OPRM1 1674/4885OPRK1 2833/4885OPRL1 2882/4885 |
| US-20160326434-A1 | LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY INCLUDING THE SAME | LEF1, AFF1, AFF2 | OPRM1 750/4885OPRK1 1276/4885OPRL1 1330/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.