SCHEMBL10015047

SCHEMBL10015047

c1ccc2c(c1)c1cc(-c3ccc(-c4cc5c6ccccc6n6c7ccccc7c(c4)c56)cc3)cc3c4ccccc4n2c13

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GPR3 P46089 1/20 0.39
KDM4E B2RXH2 3/20 0.39
POLB P06746 2/20 0.39
MEN1 O00255 2/20 0.39
MAPT P10636 2/20 0.39
KMT2A Q03164 2/20 0.39
ALDH1A1 P00352 1/20 0.39
HPGD P15428 1/20 0.39
HTT P42858 1/20 0.39
CYP1A2 P05177 1/20 0.38
CYP2C19 P33261 1/20 0.38
ATM Q13315 1/20 0.37
L3MBTL1 Q9Y468 1/20 0.37
TSPO P30536 1/20 0.35
ALKBH5 Q6P6C2 1/20 0.34
FTO Q9C0B1 1/20 0.34
RXRA P19793 1/20 0.34
RXRB P28702 1/20 0.34
CYP19A1 P11511 1/20 0.33
PTPN1 P18031 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21717850 0.96 TSPO (0.39) GPR3KDM4EPOLBMEN1MAPT
SCHEMBL10153493 0.96 GPR3 (0.42) GPR3KDM4EPOLBMEN1MAPT
SCHEMBL21454044 0.94 TSPO (0.38) GPR3KDM4EPOLBMEN1MAPT
SCHEMBL21710577 0.94 KDM4E (0.40) GPR3KDM4EPOLBMEN1MAPT
SCHEMBL10015046 0.93 GPR3 (0.41) GPR3KDM4EPOLBMEN1MAPT
SCHEMBL21710687 0.92 KDM4E (0.39) GPR3KDM4EPOLBMEN1MAPT
SCHEMBL16621733 0.92 TSPO (0.39) GPR3KDM4EPOLBMEN1MAPT
SCHEMBL24794463 0.91 TSPO (0.46) KDM4EMEN1MAPTKMT2AALDH1A1
SCHEMBL16621683 0.91 TSPO (0.46) KDM4EMEN1MAPTKMT2AALDH1A1
SCHEMBL16621693 0.91 TSPO (0.46) KDM4EMEN1MAPTKMT2AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20140167028-A1 AMINOINDOLO[3,2,1-jk]CARBAZOLE COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME CANON KABUSHIKI KAISHA (JP) 2014-06-19 US disclosed
US-20140167028-A1 AMINOINDOLO[3,2,1-jk]CARBAZOLE COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME CANON KABUSHIKI KAISHA (JP) 2014-06-19 US disclosed
US-8628864-B2 Indolo[3,2,1-jk]carbazole compound and organic light-emitting device containing the same CANON KABUSHIKI KAISHA (JP) 2014-01-14 US disclosed
US-8628864-B2 Indolo[3,2,1-jk]carbazole compound and organic light-emitting device containing the same CANON KABUSHIKI KAISHA (JP) 2014-01-14 US disclosed
WO-2013018530-A1 AMINOINDOLO[3,2,1-jk]CARBAZOLE COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME CANON KABUSHIKI KAISHA (JP) 2013-02-07 WO disclosed
US-20120075273-A1 INDOLO[3,2,1-JK]CARBAZOLE COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE CONTAINING THE SAME CANON KABUSHIKI KAISHA (JP) 2012-03-29 US disclosed
US-20120075273-A1 INDOLO[3,2,1-JK]CARBAZOLE COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE CONTAINING THE SAME CANON KABUSHIKI KAISHA (JP) 2012-03-29 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120075273-A1 INDOLO[3,2,1-JK]CARBAZOLE COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE CONTAINING THE SAME HTR3D, SYMPK, NLK GPR3 413/4885KDM4E 2644/4885POLB 4001/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.