SCHEMBL21454044

SCHEMBL21454044

c1ccc(-c2ccc(-c3cc4c5ccccc5c5ccccc5c5ccccc5n5c6ccccc6c(c3)c45)cc2)cc1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSPO P30536 1/20 0.38
KDM4E B2RXH2 5/20 0.38
ATM Q13315 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
HSD17B10 Q99714 3/20 0.36
TSHR P16473 1/20 0.36
HPGD P15428 4/20 0.36
ALDH1A1 P00352 4/20 0.36
POLB P06746 2/20 0.36
MEN1 O00255 2/20 0.36
MAPT P10636 2/20 0.36
HTT P42858 2/20 0.36
KMT2A Q03164 2/20 0.36
GPR3 P46089 1/20 0.35
PLA2G2A P14555 1/20 0.35
PLA2G4A P47712 1/20 0.35
RXRA P19793 1/20 0.35
RXRB P28702 1/20 0.35
PSEN1 P49768 1/20 0.35
PSEN2 P49810 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21717850 0.98 TSPO (0.39) TSPOKDM4EATML3MBTL1HSD17B10
SCHEMBL21710577 0.96 KDM4E (0.40) TSPOKDM4EATML3MBTL1HSD17B10
SCHEMBL21454045 0.95 TSPO (0.45) TSPOKDM4EATML3MBTL1HSD17B10
SCHEMBL21710687 0.94 KDM4E (0.39) TSPOKDM4EATML3MBTL1HSD17B10
SCHEMBL10015047 0.94 GPR3 (0.39) TSPOKDM4EATML3MBTL1HSD17B10
SCHEMBL23138557 0.93 TSPO (0.46) TSPOKDM4EATML3MBTL1HSD17B10
SCHEMBL16621683 0.93 TSPO (0.46) TSPOKDM4EATML3MBTL1HSD17B10
SCHEMBL24794463 0.93 TSPO (0.46) TSPOKDM4EATML3MBTL1HSD17B10
SCHEMBL16621693 0.93 TSPO (0.46) TSPOKDM4EATML3MBTL1HSD17B10
SCHEMBL15460057 0.93 TSPO (0.40) TSPOKDM4EATML3MBTL1HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11038121-B2 9 membered ring carbazole compounds Beijing Summer Sprout Technology Co., Ltd. (CN) 2021-06-15 US disclosed
US-20190312214-A1 9 MEMBERED RING CARBAZOLE COMPOUNDS BEIJING SUMMER SPROUT TECHNOLOGY CO., LTD (CN) 2019-10-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11038121-B2 9 membered ring carbazole compounds SLC25A21, OCIAD2, OXA1L TSPO 136/4885KDM4E 3723/4885ATM 3337/4885
US-20190312214-A1 9 MEMBERED RING CARBAZOLE COMPOUNDS SLC25A21, OCIAD2, OXA1L TSPO 136/4885KDM4E 3723/4885ATM 3337/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.