Sugi Predict

Sugi Predict / Compounds / SCHEMBL10015055

SCHEMBL10015055

SCHEMBL10015055

c1cc(-c2cccc(-c3cc4c5ccccc5n5c6ccccc6c(c3)c45)c2)cc(-c2ccc3c(ccc4ccccc43)c2)c1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ALDH1A1 P00352 3/20 0.39
▸ HSD17B10 Q99714 3/20 0.39
▸ CYP1B1 Q16678 2/20 0.39
▸ HIF1A Q16665 1/20 0.39
▸ HPRT1 P00492 3/20 0.37
▸ CYP1A2 P05177 5/20 0.37
▸ ERBB2 P04626 1/20 0.37
▸ FYN P06241 1/20 0.37
▸ MAOA P21397 1/20 0.37
▸ ACHE P22303 1/20 0.37
▸ AHR P35869 1/20 0.37
▸ ESR1 P03372 3/20 0.36
▸ ESR2 Q92731 3/20 0.36
▸ HSD17B1 P14061 6/20 0.36
▸ HSD17B2 P37059 6/20 0.36
▸ CYP3A4 P08684 2/20 0.35
▸ CYP2D6 P10635 2/20 0.35
▸ CYP2C9 P11712 2/20 0.35
▸ CYP2B6 P20813 2/20 0.35
▸ CYP2C19 P33261 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21717861 0.95 ALDH1A1 (0.42) ALDH1A1HSD17B10CYP1B1HIF1AHPRT1
SCHEMBL15460063 0.93 HSD17B1 (0.39) ALDH1A1HSD17B10CYP1B1HIF1AHPRT1
SCHEMBL21717827 0.90 ALDH1A1 (0.40) ALDH1A1HSD17B10CYP1B1HIF1AHPRT1
SCHEMBL21710651 0.89 ALDH1A1 (0.41) ALDH1A1HSD17B10CYP1B1HIF1AHPRT1
SCHEMBL15460078 0.88 HSD17B1 (0.42) ALDH1A1CYP1A2ESR1ESR2HSD17B1
SCHEMBL22858085 0.87 ALDH1A1 (0.36) ALDH1A1HSD17B10CYP1B1HIF1AHPRT1
SCHEMBL10015061 0.86 KDM4E (0.36) ALDH1A1HSD17B10CYP1A2ESR1CYP2C19
SCHEMBL10015060 0.85 CYP11B1 (0.42) ALDH1A1HSD17B10CYP1B1HIF1ACYP1A2
SCHEMBL15460054 0.84 TSPO (0.40) ALDH1A1HSD17B10MAOAESR1TSHR
SCHEMBL15460057 0.84 TSPO (0.40) ALDH1A1HSD17B10MAOAESR1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8628864-B2 Indolo[3,2,1-jk]carbazole compound and organic light-emitting device containing the same CANON KABUSHIKI KAISHA (JP) 2014-01-14 — — US disclosed
US-8628864-B2 Indolo[3,2,1-jk]carbazole compound and organic light-emitting device containing the same CANON KABUSHIKI KAISHA (JP) 2014-01-14 — — US disclosed
US-20120075273-A1 INDOLO[3,2,1-JK]CARBAZOLE COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE CONTAINING THE SAME CANON KABUSHIKI KAISHA (JP) 2012-03-29 — — US disclosed
US-20120075273-A1 INDOLO[3,2,1-JK]CARBAZOLE COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE CONTAINING THE SAME CANON KABUSHIKI KAISHA (JP) 2012-03-29 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120075273-A1 INDOLO[3,2,1-JK]CARBAZOLE COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE CONTAINING THE SAME HTR3D, SYMPK, NLK ALDH1A1 1696/4885HSD17B10 2594/4885CYP1B1 206/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.