Sugi Predict

Sugi Predict / Compounds / SCHEMBL10015296

SCHEMBL10015296

SCHEMBL10015296

c1ccc(-c2ccc3c(c2)c2cc(-c4ccccc4)ccc2n3-c2ccc(-c3cncc(-c4cc(-n5c6ccccc6c6ccccc65)cc(-n5c6ccccc6c6ccccc65)c4)c3)cc2)cc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ KDM4E B2RXH2 1/20 0.44
▸ ATM Q13315 1/20 0.44
▸ L3MBTL1 Q9Y468 1/20 0.44
▸ CYP11B1 P15538 4/20 0.38
▸ CYP11B2 P19099 4/20 0.38
▸ MKNK1 Q9BUB5 1/20 0.38
▸ MKNK2 Q9HBH9 1/20 0.38
▸ TSPO P30536 1/20 0.38
▸ HDAC4 P56524 1/20 0.38
▸ CHRNB4 P30926 1/20 0.36
▸ CHRNA3 P32297 1/20 0.36
▸ RAC2 P15153 1/20 0.36
▸ RAC3 P60763 1/20 0.36
▸ CDC42 P60953 1/20 0.36
▸ RAC1 P63000 1/20 0.36
▸ NR3C1 P04150 1/20 0.36
▸ PTGER4 P35408 1/20 0.34
▸ KMT2A Q03164 2/20 0.33
▸ MEN1 O00255 1/20 0.33
▸ HSP90AA1 P07900 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10015292 1.00 KDM4E (0.44) KDM4EATML3MBTL1CYP11B1CYP11B2
SCHEMBL22252920 0.95 L3MBTL1 (0.45) KDM4EATML3MBTL1CYP11B1CYP11B2
SCHEMBL11987828 0.95 L3MBTL1 (0.49) KDM4EATML3MBTL1CYP11B1CYP11B2
SCHEMBL11987839 0.92 L3MBTL1 (0.47) KDM4EATML3MBTL1CYP11B1CYP11B2
SCHEMBL11981064 0.92 L3MBTL1 (0.53) KDM4EATML3MBTL1CYP11B1CYP11B2
SCHEMBL11987852 0.92 KDM4E (0.47) KDM4EATML3MBTL1CYP11B1CYP11B2
SCHEMBL11987847 0.92 KDM4E (0.47) KDM4EATML3MBTL1CYP11B1CYP11B2
SCHEMBL19596286 0.90 L3MBTL1 (0.53) KDM4EATML3MBTL1TSPOHDAC4
SCHEMBL21531896 0.90 L3MBTL1 (0.53) KDM4EATML3MBTL1TSPOHDAC4
SCHEMBL17998179 0.90 L3MBTL1 (0.53) KDM4EATML3MBTL1TSPOHDAC4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20120280221-A1 MATERIAL FOR ORGANIC PHOTOELECTRIC DEVICE INCLUDING ELECTRON TRANSPORTING UNIT AND HOLE TRANSPORTING UNIT, AND ORGANIC PHOTOELECTRIC DEVICE INCLUDING THE SAME CHEIL INDUSTRIES, INC. (KR) 2012-11-08 — — US disclosed
US-20120280221-A1 MATERIAL FOR ORGANIC PHOTOELECTRIC DEVICE INCLUDING ELECTRON TRANSPORTING UNIT AND HOLE TRANSPORTING UNIT, AND ORGANIC PHOTOELECTRIC DEVICE INCLUDING THE SAME CHEIL INDUSTRIES, INC. (KR) 2012-11-08 — — US disclosed
US-8247805-B2 Material for organic photoelectric device including electron transporting unit and hole transporting unit, and organic photoelectric device including the same CHEIL INDUSTRIES, INC. (KR) 2012-08-21 — — US disclosed
US-8247805-B2 Material for organic photoelectric device including electron transporting unit and hole transporting unit, and organic photoelectric device including the same CHEIL INDUSTRIES, INC. (KR) 2012-08-21 — — US disclosed
US-8120243-B2 Material for organic photoelectric device, and organic photoelectric device thereby CHEIL INDUSTRIES, INC. (KR) 2012-02-21 — — US disclosed
US-8120243-B2 Material for organic photoelectric device, and organic photoelectric device thereby CHEIL INDUSTRIES, INC. (KR) 2012-02-21 — — US disclosed
US-20120012830-A1 MATERIAL FOR ORGANIC PHOTOELECTRIC DEVICE, AND ORGANIC PHOTOELECTRIC DEVICE THEREBY CHEIL INDUSTRIES, INC. (KR) 2012-01-19 — — US disclosed
US-20120012830-A1 MATERIAL FOR ORGANIC PHOTOELECTRIC DEVICE, AND ORGANIC PHOTOELECTRIC DEVICE THEREBY CHEIL INDUSTRIES, INC. (KR) 2012-01-19 — — US disclosed
US-20100213826-A1 Material for organic photoelectric device, and organic photoelectric device thereby CHEIL INDUSTRIES, INC. (KR) 2010-08-26 — — US disclosed
US-20100213826-A1 Material for organic photoelectric device, and organic photoelectric device thereby CHEIL INDUSTRIES, INC. (KR) 2010-08-26 — — US disclosed
US-20100155706-A1 Material for organic photoelectric device including electron transporting unit and hole transporting unit, and organic photoelectric device including the same CHEIL INDUSTRIES, INC. (KR) 2010-06-24 — — US disclosed
US-20100155706-A1 Material for organic photoelectric device including electron transporting unit and hole transporting unit, and organic photoelectric device including the same CHEIL INDUSTRIES, INC. (KR) 2010-06-24 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100213826-A1 Material for organic photoelectric device, and organic photoelectric device thereby HCN1, HCN2, HCN4 KDM4E 4279/4885ATM 4104/4885L3MBTL1 1724/4885
US-20100155706-A1 Material for organic photoelectric device including electron transporting unit and hole transporting unit, and organic photoelectric device including the same SLC25A21, MCU, SLC25A11 KDM4E 2771/4885ATM 4392/4885L3MBTL1 3567/4885
US-20120280221-A1 MATERIAL FOR ORGANIC PHOTOELECTRIC DEVICE INCLUDING ELECTRON TRANSPORTING UNIT AND HOLE TRANSPORTING UNIT, AND ORGANIC PHOTOELECTRIC DEVICE INCLUDING THE SAME SLC25A21, MCU, SLC25A11 KDM4E 2530/4885ATM 4333/4885L3MBTL1 3391/4885
US-20120012830-A1 MATERIAL FOR ORGANIC PHOTOELECTRIC DEVICE, AND ORGANIC PHOTOELECTRIC DEVICE THEREBY HCN1, HCN2, HCN4 KDM4E 4279/4885ATM 4104/4885L3MBTL1 1724/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.