SCHEMBL11987828

SCHEMBL11987828

c1ccc(-c2ccc3c(c2)c2cc(-c4ccccc4)ccc2n3-c2ccc(-c3cncc(-c4ccc(-n5c6ccccc6c6ccccc65)cc4)c3)cc2)cc1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 2/20 0.49
KDM4E B2RXH2 1/20 0.49
ATM Q13315 1/20 0.49
CYP11B1 P15538 3/20 0.41
CYP11B2 P19099 3/20 0.41
MKNK1 Q9BUB5 1/20 0.41
MKNK2 Q9HBH9 1/20 0.41
TSPO P30536 1/20 0.40
HDAC4 P56524 1/20 0.40
RAC2 P15153 1/20 0.39
RAC3 P60763 1/20 0.39
CDC42 P60953 1/20 0.39
RAC1 P63000 1/20 0.39
NR3C1 P04150 1/20 0.39
CHRNB4 P30926 1/20 0.37
CHRNA3 P32297 1/20 0.37
CHRNA7 P36544 1/20 0.36
PTGER4 P35408 1/20 0.36
KMT2A Q03164 3/20 0.36
MEN1 O00255 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11981064 0.97 L3MBTL1 (0.53) L3MBTL1KDM4EATMCYP11B1CYP11B2
SCHEMBL11987833 0.95 CYP11B1 (0.44) L3MBTL1KDM4EATMCYP11B1CYP11B2
SCHEMBL17952947 0.95 CYP11B1 (0.44) L3MBTL1KDM4EATMCYP11B1CYP11B2
SCHEMBL11987839 0.95 L3MBTL1 (0.47) L3MBTL1KDM4EATMCYP11B1CYP11B2
SCHEMBL10015292 0.95 KDM4E (0.44) L3MBTL1KDM4EATMCYP11B1CYP11B2
SCHEMBL10015296 0.95 KDM4E (0.44) L3MBTL1KDM4EATMCYP11B1CYP11B2
SCHEMBL22252920 0.92 L3MBTL1 (0.45) L3MBTL1KDM4EATMCYP11B1CYP11B2
SCHEMBL11987863 0.92 KDM4E (0.41) L3MBTL1KDM4EATMCYP11B1CYP11B2
SCHEMBL15159202 0.92 ATM (0.44) L3MBTL1KDM4EATMCYP11B1CYP11B2
SCHEMBL17714804 0.91 KDM4E (0.44) L3MBTL1KDM4EATMCYP11B1CYP11B2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20120280221-A1 MATERIAL FOR ORGANIC PHOTOELECTRIC DEVICE INCLUDING ELECTRON TRANSPORTING UNIT AND HOLE TRANSPORTING UNIT, AND ORGANIC PHOTOELECTRIC DEVICE INCLUDING THE SAME CHEIL INDUSTRIES, INC. (KR) 2012-11-08 US disclosed
US-20120280221-A1 MATERIAL FOR ORGANIC PHOTOELECTRIC DEVICE INCLUDING ELECTRON TRANSPORTING UNIT AND HOLE TRANSPORTING UNIT, AND ORGANIC PHOTOELECTRIC DEVICE INCLUDING THE SAME CHEIL INDUSTRIES, INC. (KR) 2012-11-08 US disclosed
US-8247805-B2 Material for organic photoelectric device including electron transporting unit and hole transporting unit, and organic photoelectric device including the same CHEIL INDUSTRIES, INC. (KR) 2012-08-21 US disclosed
US-8247805-B2 Material for organic photoelectric device including electron transporting unit and hole transporting unit, and organic photoelectric device including the same CHEIL INDUSTRIES, INC. (KR) 2012-08-21 US disclosed
US-20100155706-A1 Material for organic photoelectric device including electron transporting unit and hole transporting unit, and organic photoelectric device including the same CHEIL INDUSTRIES, INC. (KR) 2010-06-24 US disclosed
US-20100155706-A1 Material for organic photoelectric device including electron transporting unit and hole transporting unit, and organic photoelectric device including the same CHEIL INDUSTRIES, INC. (KR) 2010-06-24 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100155706-A1 Material for organic photoelectric device including electron transporting unit and hole transporting unit, and organic photoelectric device including the same SLC25A21, MCU, SLC25A11 L3MBTL1 3567/4885KDM4E 2771/4885ATM 4392/4885
US-20120280221-A1 MATERIAL FOR ORGANIC PHOTOELECTRIC DEVICE INCLUDING ELECTRON TRANSPORTING UNIT AND HOLE TRANSPORTING UNIT, AND ORGANIC PHOTOELECTRIC DEVICE INCLUDING THE SAME SLC25A21, MCU, SLC25A11 L3MBTL1 3391/4885KDM4E 2530/4885ATM 4333/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.