Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.41 |
| ▸ | FKBP1A | P62942 | 14/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10015348 | 0.83 | SPHK1 (0.46) | SPHK1FKBP1A | |
| SCHEMBL19658364 | 0.79 | ACE (0.35) | — | |
| SCHEMBL10015341 | 0.78 | SPHK1 (0.49) | SPHK1FKBP1A | |
| SCHEMBL9477001 | 0.78 | ACE (0.40) | SPHK1 | |
| SCHEMBL16116973 | 0.77 | SPHK1 (0.48) | SPHK1FKBP1A | |
| SCHEMBL16116984 | 0.77 | SPHK1 (0.48) | SPHK1FKBP1A | |
| SCHEMBL10015351 | 0.76 | SPHK1 (0.40) | SPHK1FKBP1A | |
| SCHEMBL19658285 | 0.75 | ACE (0.37) | SPHK1 | |
| SCHEMBL19658286 | 0.75 | ACE (0.37) | SPHK1 | |
| SCHEMBL5497995 | 0.74 | FKBP1A (0.49) | SPHK1FKBP1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120027859-A1 | Biodegradable Proline-Based Polymers | MEDIVAS, LLC | 2012-02-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120027859-A1 | Biodegradable Proline-Based Polymers | EPRS1, PRAP1, NPEPPS | SPHK1 3261/4885FKBP1A 35/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.