Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 9/20 | 0.54 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15205568 | 1.00 | EPHX1 (0.54) | EPHX1EPHX2HTTNPC1MEN1 | |
| SCHEMBL692430 | 0.98 | EPHX1 (0.51) | EPHX1EPHX2MEN1ALDH1A1MAPT | |
| SCHEMBL692429 | 0.98 | EPHX1 (0.51) | EPHX1EPHX2MEN1ALDH1A1MAPT | |
| SCHEMBL3087847 | 0.88 | MEN1 (0.60) | MEN1ALDH1A1MAPTHPGDKMT2A | |
| SCHEMBL3960853 | 0.88 | MEN1 (0.60) | MEN1ALDH1A1MAPTHPGDKMT2A | |
| SCHEMBL18556750 | 0.87 | HTT (0.61) | EPHX1EPHX2HTTNPC1ALDH1A1 | |
| SCHEMBL12923999 | 0.87 | CNR2 (0.52) | EPHX1EPHX2MEN1ALDH1A1MAPT | |
| SCHEMBL14671476 | 0.86 | MEN1 (0.51) | MEN1ALDH1A1MAPTHPGDKMT2A | |
| SCHEMBL14671474 | 0.83 | CNR1 (0.48) | MEN1ALDH1A1MAPTHPGDKMT2A | |
| SCHEMBL21226235 | 0.80 | SMN1; SMN2 (0.59) | EPHX1EPHX2HTTNPC1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2636666-B1 | TRANS-2-DECENOIC ACID DERIVATIVE AND MEDICAMENT CONTAINING SAME | NAGOYA INDUSTRIAL SCIENCE RES INSTITUTE (JP) | 2018-01-10 | — | — | EP | disclosed |
| CN-103189350-B | Trans-2-decenoic acid derivative and drug containing same | NAGOYA INDUSTRIAL SCIENCE RESRARCH INSTITUTE (JP) | 2016-04-27 | — | — | CN | disclosed |
| US-20150297562-A1 | ANALGESIC | NIPPON ZOKI PHARMACEUTICAL CO., LTD. (JP) | 2015-10-22 | — | — | US | disclosed |
| US-20150297562-A1 | ANALGESIC | NIPPON ZOKI PHARMACEUTICAL CO., LTD. (JP) | 2015-10-22 | — | — | US | disclosed |
| US-20150297562-A1 | ANALGESIC | NIPPON ZOKI PHARMACEUTICAL CO., LTD. (JP) | 2015-10-22 | — | — | US | disclosed |
| US-8987486-B2 | Trans-2-decenoic acid derivative and pharmaceutical agent containing the same | NAGOYA INDUSTRIAL SCIENCE RESEARCH INSTITUTE (JP) | 2015-03-24 | — | — | US | disclosed |
| US-8987486-B2 | Trans-2-decenoic acid derivative and pharmaceutical agent containing the same | NAGOYA INDUSTRIAL SCIENCE RESEARCH INSTITUTE (JP) | 2015-03-24 | — | — | US | disclosed |
| US-8987486-B2 | Trans-2-decenoic acid derivative and pharmaceutical agent containing the same | NAGOYA INDUSTRIAL SCIENCE RESEARCH INSTITUTE (JP) | 2015-03-24 | — | — | US | disclosed |
| EP-2842553-A1 | ANALGESIC | Nippon Zoki Pharmaceutical Co., Ltd. (JP) | 2015-03-04 | — | — | EP | disclosed |
| EP-2842553-A1 | ANALGESIC | Nippon Zoki Pharmaceutical Co., Ltd. (JP) | 2015-03-04 | — | — | EP | disclosed |
| EP-2636666-A1 | TRANS-2-DECENOIC ACID DERIVATIVE AND MEDICAMENT CONTAINING SAME | Nagoya Industrial Science Research Institute (JP) | 2013-09-11 | — | — | EP | disclosed |
| EP-2636666-A1 | TRANS-2-DECENOIC ACID DERIVATIVE AND MEDICAMENT CONTAINING SAME | Nagoya Industrial Science Research Institute (JP) | 2013-09-11 | — | — | EP | disclosed |
| US-20130225837-A1 | TRANS-2-DECENOIC ACID DERIVATIVE AND PHARMACEUTICAL AGENT CONTAINING THE SAME | NIPPON ZOKI PHARMACEUTICAL CO., LTD. (JP) | 2013-08-29 | — | — | US | disclosed |
| US-20130225837-A1 | TRANS-2-DECENOIC ACID DERIVATIVE AND PHARMACEUTICAL AGENT CONTAINING THE SAME | NIPPON ZOKI PHARMACEUTICAL CO., LTD. (JP) | 2013-08-29 | — | — | US | disclosed |
| US-20130225837-A1 | TRANS-2-DECENOIC ACID DERIVATIVE AND PHARMACEUTICAL AGENT CONTAINING THE SAME | NIPPON ZOKI PHARMACEUTICAL CO., LTD. (JP) | 2013-08-29 | — | — | US | disclosed |
| CN-103189350-A | Trans-2-decenoic acid derivative and drug containing same | NAGOYA IND SCIENCE RES INST | 2013-07-03 | — | — | CN | disclosed |
| WO-2012060396-A1 | TRANS-2-DECENOIC ACID DERIVATIVE AND MEDICAMENT CONTAINING SAME | 財団法人名古屋産業科学研究所 (JP) | 2012-05-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150297562-A1 | ANALGESIC | OPRK1, OPRL1, OPRD1 | EPHX1 669/4885EPHX2 570/4885HTT 174/4885 |
| US-20130225837-A1 | TRANS-2-DECENOIC ACID DERIVATIVE AND PHARMACEUTICAL AGENT CONTAINING THE SAME | BDNF, NTRK2, NGF | EPHX1 3282/4885EPHX2 2515/4885HTT 568/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.