Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LCK | P06239 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 3/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.31 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.31 |
| ▸ | GABRR3 | A8MPY1 | 1/20 | 0.31 |
| ▸ | GABRP | O00591 | 1/20 | 0.31 |
| ▸ | GABRD | O14764 | 1/20 | 0.31 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.31 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.31 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.31 |
| ▸ | GABRR1 | P24046 | 1/20 | 0.31 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.31 |
| ▸ | GABRR2 | P28476 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16638615 | 0.97 | LCK (0.32) | LCKBLMKMT2AALOX15PMP22 | |
| SCHEMBL899927 | 0.89 | TDP1 (0.37) | BLMKMT2AALOX15PMP22LMNA | |
| SCHEMBL16638613 | 0.87 | CYP2C9 (0.34) | HDAC6CYP2C9CYP2C19 | |
| SCHEMBL13154384 | 0.87 | LCK (0.35) | LCK | |
| SCHEMBL808456 | 0.86 | TDP1 (0.36) | BLMKMT2AALOX15PMP22LMNA | |
| Hydrochloric Acid SCHEMBL9711107 | 0.86 | ALOX15 (0.35) | BLMKMT2AALOX15PMP22LMNA | |
| Ammonia Solution, Strong SCHEMBL10870270 | 0.86 | ALOX15 (0.35) | BLMKMT2AALOX15PMP22LMNA | |
| SCHEMBL20998889 | 0.86 | TDP1 (0.36) | BLMKMT2AALOX15PMP22LMNA | |
| SCHEMBL13154489 | 0.85 | — | — | |
| SCHEMBL12482710 | 0.85 | LMNA (0.39) | LCKBLMKMT2AALOX15LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012017118-A1 | CARBON NANOHORNS COMPRISING DENDRIMERS ON THEIR SURFACE AS NON -VIRAL VECTORS FOR GENE THERAPY | UNIVERSIDAD CASTILLA LA MANCHA (50%) (ES) | 2012-02-09 | — | — | WO | disclosed |
| WO-2012017119-A2 | NON-VIRAL VECTORS FOR GENE THERAPY | UNIVERSIDAD CASTILLA LA MANCHA (ES) | 2012-02-09 | — | — | WO | disclosed |