Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LCK | P06239 | 1/20 | 0.32 |
| ▸ | EYA2 | O00167 | 1/20 | 0.31 |
| ▸ | APP | P05067 | 1/20 | 0.31 |
| ▸ | ACE | P12821 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
| ▸ | BLM | P54132 | 1/20 | 0.30 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10017445 | 0.97 | LCK (0.33) | LCKTDP1ALOX15BLMPMP22 | |
| SCHEMBL20998889 | 0.89 | TDP1 (0.36) | EYA2APPACETDP1ALOX15 | |
| SCHEMBL808456 | 0.89 | TDP1 (0.36) | EYA2APPACETDP1ALOX15 | |
| SCHEMBL899927 | 0.87 | TDP1 (0.37) | EYA2APPACETDP1ALOX15 | |
| SCHEMBL13154384 | 0.85 | LCK (0.35) | LCK | |
| SCHEMBL16638613 | 0.85 | CYP2C9 (0.34) | — | |
| Ammonia Solution, Strong SCHEMBL10870270 | 0.84 | ALOX15 (0.35) | EYA2APPACETDP1ALOX15 | |
| Hydrochloric Acid SCHEMBL9711107 | 0.84 | ALOX15 (0.35) | EYA2APPACETDP1ALOX15 | |
| SCHEMBL13154489 | 0.83 | — | — | |
| SCHEMBL12482710 | 0.83 | LMNA (0.39) | LCKALOX15BLMKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9006487-B2 | Amine-containing lipids and uses thereof | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2015-04-14 | — | — | US | disclosed |