Phthalimide

Phthalimide

SCHEMBL1001750

C1CCNC1.O=C1NC(=O)c2ccccc21

nearest known ligand 0.68

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GSK3B P49841 1/20 0.68
CASP3 P42574 2/20 0.58
CASP7 P55210 2/20 0.58
CASP6 P55212 2/20 0.58
CASP8 Q14790 2/20 0.58
CASP2 P42575 1/20 0.58
TDP2 O95551 1/20 0.45
CASP9 P55211 1/20 0.45
MAP3K14 Q99558 1/20 0.45
PARP1 P09874 4/20 0.45
PDGFRA P16234 1/20 0.45
FER P16591 1/20 0.45
LTK P29376 1/20 0.45
CDK8 P49336 1/20 0.45
ACVR1 Q04771 1/20 0.45
LRRK2 Q5S007 1/20 0.45
DYRK1B Q9Y463 1/20 0.45
LMNA P02545 2/20 0.42
MAPK1 P28482 2/20 0.42
SMN1; SMN2 Q16637 2/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Phthalimide SCHEMBL27169395 0.98 GSK3B (0.65) GSK3BCASP3CASP7CASP6CASP8
Phthalimide SCHEMBL698223 0.98 GSK3B (0.65) GSK3BCASP3CASP7CASP6CASP8
Phthalimide SCHEMBL14861040 0.93 GSK3B (0.65) GSK3BCASP3CASP7CASP6CASP8
Phthalimide SCHEMBL28810882 0.91 GSK3B (0.75) GSK3BCASP3CASP7CASP6CASP8
Phthalimide SCHEMBL28372975 0.85 GSK3B (0.83) GSK3BCASP3CASP7CASP6CASP8
Phthalimide SCHEMBL27772865 0.83 GSK3B (0.79) GSK3BCASP3CASP7CASP6CASP8
Phthalimide SCHEMBL29366030 0.83 GSK3B (1.00) GSK3BCASP3CASP7CASP6CASP8
Phthalimide SCHEMBL30125197 0.83 GSK3B (1.00) GSK3BCASP3CASP7CASP6CASP8
Phthalimide SCHEMBL11040503 0.83 GSK3B (1.00) GSK3BCASP3CASP7CASP6CASP8
Phthalimide SCHEMBL10192661 0.83 GSK3B (1.00) GSK3BCASP3CASP7CASP6CASP8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 149 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4268651-A1 FIBER-TREATING AGENT Kao Corporation (JP) 2023-11-01 EP claimed
EP-4268653-A1 FIBER-TREATING AGENT Kao Corporation (JP) 2023-11-01 EP claimed
EP-4268652-A1 FIBER TREATMENT AGENT Kao Corporation (JP) 2023-11-01 EP claimed
EP-4268650-A1 FIBER TREATMENT AGENT Kao Corporation (JP) 2023-11-01 EP claimed
CN-116783347-A Fiber treatment agent 花王株式会社 2023-09-19 CN claimed
CN-116745484-A fiber treatment agent 花王株式会社 2023-09-12 CN claimed
CN-116710610-A Fiber treatment agent 花王株式会社 2023-09-05 CN claimed
CN-116648538-A Fiber treatment agent 花王株式会社 2023-08-25 CN claimed
US-20230087728-A1 FIBER TREATMENT AGENT COMPOSITION KAO CORPORATION (JP) 2023-03-23 US claimed
EP-4018864-A1 HUMAN HAIR FIBER TREATMENT AGENT Kao Corporation (JP) 2022-06-29 EP claimed
CN-114080213-A Hair treatment method 花王株式会社 2022-02-22 CN claimed
US-20140235885-A1 COPOLYMERS OF EPOXY COMPOUNDS AND AMINO SILANES MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2014-08-21 US claimed
US-11951198-B2 Method and kit for processing hair LIW PATENT COMPANY LIMITED BY GUARANTEE (IE) 2024-04-09 US disclosed
US-20240068156-A1 FIBER-TREATING AGENT KAO CORPORATION (JP) 2024-02-29 US disclosed
US-20240058249-A1 FIBER-TREATING AGENT KAO CORPORATION (JP) 2024-02-22 US disclosed
US-20240060234-A1 FIBER-TREATING AGENT KAO CORPORATION (JP) 2024-02-22 US disclosed
WO-2009061371-A2 COPOLYMERS OF EPOXY COMPOUNDS AND AMINO SILANES MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2009-05-14 WO disclosed
WO-2009061360-A1 PERSONAL CARE COMPOSITION COMPRISING A REACTION PRODUCT OF EPOXY COMPOUND AND AMINO SILANE MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2009-05-14 WO disclosed
US-20090118421-A1 COPOLYMER OF EPOXY COMPOUNDS AND AMINO SILANES MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2009-05-07 US disclosed
US-20090117793-A1 Textiles treated with copolymers of epoxy compounds and amino silanes having enhanced wet-strength MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2009-05-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140235885-A1 COPOLYMERS OF EPOXY COMPOUNDS AND AMINO SILANES OXGR1, SRM, OXER1 GSK3B 4762/4885CASP3 3002/4885CASP7 4606/4885
US-11951198-B2 Method and kit for processing hair KRT18, PHB1, BTD GSK3B 2260/4885CASP3 998/4885CASP7 256/4885
US-20230087728-A1 FIBER TREATMENT AGENT COMPOSITION SMARCA1, SMARCA2, COL1A1 GSK3B 4111/4885CASP3 2435/4885CASP7 1814/4885
US-20240058249-A1 FIBER-TREATING AGENT H1-5, FAU, H1-3 GSK3B 3886/4885CASP3 615/4885CASP7 768/4885
US-20240068156-A1 FIBER-TREATING AGENT H1-5, H1-3, H1-4 GSK3B 3824/4885CASP3 1000/4885CASP7 1148/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.