Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | BTK | Q06187 | 4/20 | 0.33 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | MGAT2 | Q10469 | 1/20 | 0.32 |
| ▸ | DHFR | P00374 | 1/20 | 0.31 |
| ▸ | CYP17A1 | P05093 | 3/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.31 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.30 |
| ▸ | MTOR | P42345 | 1/20 | 0.30 |
| ▸ | BLK | P51451 | 1/20 | 0.30 |
| ▸ | BMX | P51813 | 1/20 | 0.30 |
| ▸ | JAK3 | P52333 | 1/20 | 0.30 |
| ▸ | CDC7 | O00311 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10018487 | 0.87 | ADH5 (0.36) | HTTBTKAOC3 | |
| SCHEMBL12086575 | 0.86 | HTT (0.32) | HTTMAPT | |
| SCHEMBL16482337 | 0.84 | RPS6KA3 (0.41) | HTTBTKTP53MEN1KMT2A | |
| SCHEMBL16482338 | 0.84 | AOC3 (0.33) | HTTBTKTDP1MEN1KMT2A | |
| SCHEMBL16482012 | 0.82 | MEN1 (0.38) | HTTTDP1MEN1KMT2ACYP1A2 | |
| SCHEMBL13098376 | 0.81 | AOC3 (0.36) | HTTDHFRAOC3GRM4 | |
| SCHEMBL16482132 | 0.81 | MGAT2 (0.52) | MGAT2CYP17A1CYP1A2 | |
| SCHEMBL5028258 | 0.80 | CYP19A1 (0.38) | CYP17A1CYP1A2AOC3 | |
| SCHEMBL16482061 | 0.80 | PRKCI (0.44) | HTTMGAT2AOC3MTOR | |
| SCHEMBL10018491 | 0.79 | HTR7 (0.37) | HTTMGAT2CYP1A2MAPTAOC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8101699-B2 | Electron-transporting polymers | GENERAL ELECTRIC COMPANY (US) | 2012-01-24 | — | — | US | disclosed |
| US-8101699-B2 | Electron-transporting polymers | GENERAL ELECTRIC COMPANY (US) | 2012-01-24 | — | — | US | disclosed |
| WO-2010065515-A1 | ELECTRON-TRANSPORTING POLYMERS | GENERAL ELECTRIC COMPANY (US) | 2010-06-10 | — | — | WO | disclosed |
| US-20100137538-A1 | ELECTRON-TRANSPORTING POLYMERS | GENERAL ELECTRIC COMPANY (US) | 2010-06-03 | — | — | US | disclosed |
| US-20100137538-A1 | ELECTRON-TRANSPORTING POLYMERS | GENERAL ELECTRIC COMPANY (US) | 2010-06-03 | — | — | US | disclosed |