SCHEMBL16482132

SCHEMBL16482132

COc1cccc(-c2ccc(-n3c4ccncc4c4cnccc43)cc2C)c1

nearest known ligand 0.52

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
MGAT2 Q10469 1/20 0.52
DGAT2 Q96PD7 12/20 0.46
RPS6KA3 P51812 1/20 0.44
SLC22A12 Q96S37 1/20 0.44
CYP17A1 P05093 1/20 0.42
CYP1A2 P05177 1/20 0.42
CYP11B1 P15538 2/20 0.42
CYP11B2 P19099 2/20 0.42
MAPK1 P28482 1/20 0.42
KDR P35968 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16482337 0.85 RPS6KA3 (0.41) RPS6KA3CYP17A1
SCHEMBL16482012 0.83 MEN1 (0.38) CYP1A2
SCHEMBL13098376 0.82 AOC3 (0.36)
SCHEMBL16481995 0.81 SLC2A1 (0.50) DGAT2
SCHEMBL5028258 0.81 CYP19A1 (0.38) CYP17A1CYP1A2
SCHEMBL10018490 0.81 HTT (0.35) MGAT2CYP17A1CYP1A2
SCHEMBL16482061 0.81 PRKCI (0.44) MGAT2
SCHEMBL10018491 0.80 HTR7 (0.37) MGAT2DGAT2CYP1A2
SCHEMBL16481983 0.80 AKR1C3 (0.47)
SCHEMBL261774 0.79 MAOA (0.43) CYP17A1CYP1A2CYP11B2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10862048-B2 Organic electroluminescent device, thin luminous film, display apparatus, and lighting apparatus MERCK PATENT GMBH (DE) 2020-12-08 US disclosed
US-20180212157-A1 ORGANIC ELECTROLUMINESCENT DEVICE, THIN LUMINOUS FILM, DISPLAY APPARATUS, AND LIGHTING APPARATUS MERCK PERFORMANCE MATERIALS GERMANY GMBH (DE) 2018-07-26 US disclosed
US-20180212157-A1 ORGANIC ELECTROLUMINESCENT DEVICE, THIN LUMINOUS FILM, DISPLAY APPARATUS, AND LIGHTING APPARATUS MERCK PERFORMANCE MATERIALS GERMANY GMBH (DE) 2018-07-26 US disclosed
US-9935269-B2 Electroluminescence element Konica Minolta, Inc. (JP) 2018-04-03 US disclosed
US-9935269-B2 Electroluminescence element Konica Minolta, Inc. (JP) 2018-04-03 US disclosed
US-20160372683-A1 ORGANIC ELECTROLUMINESCENCE ELEMENT, DISPLAY DEVICE, ILLUMINATION DEVICE, AND LIGHT-EMITTING COMPOSITION Konica Minolta, Inc. (JP) 2016-12-22 US disclosed
US-20160372683-A1 ORGANIC ELECTROLUMINESCENCE ELEMENT, DISPLAY DEVICE, ILLUMINATION DEVICE, AND LIGHT-EMITTING COMPOSITION Konica Minolta, Inc. (JP) 2016-12-22 US disclosed
US-20160197282-A1 ORGANIC ELECTROLUMINESCENT ELEMENT, LIGHT EMITTING DEVICE, LIGHTING DEVICE, DISPLAY DEVICE AND ELECTRONIC DEVICE Konica Minolta, Inc. (JP) 2016-07-07 US disclosed
US-20160197282-A1 ORGANIC ELECTROLUMINESCENT ELEMENT, LIGHT EMITTING DEVICE, LIGHTING DEVICE, DISPLAY DEVICE AND ELECTRONIC DEVICE Konica Minolta, Inc. (JP) 2016-07-07 US disclosed
US-20150287927-A1 ELECTROLUMINESCENCE ELEMENT Konica Minolta, Inc. (JP) 2015-10-08 US disclosed
US-20150287927-A1 ELECTROLUMINESCENCE ELEMENT Konica Minolta, Inc. (JP) 2015-10-08 US disclosed
WO-2014057971-A1 ELECTROLUMINESCENCE ELEMENT コニカミノルタ株式会社 (JP) 2014-04-17 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180212157-A1 ORGANIC ELECTROLUMINESCENT DEVICE, THIN LUMINOUS FILM, DISPLAY APPARATUS, AND LIGHTING APPARATUS LPO, L1CAM, EML4 MGAT2 2836/4885DGAT2 2353/4885RPS6KA3 4380/4885
US-10862048-B2 Organic electroluminescent device, thin luminous film, display apparatus, and lighting apparatus LPO, L1CAM, EML4 MGAT2 2836/4885DGAT2 2353/4885RPS6KA3 4380/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.