SCHEMBL16482012

SCHEMBL16482012

Cc1cc(-n2c3ccncc3c3cnccc32)ccc1-c1cccc(Br)c1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 4/20 0.38
KMT2A Q03164 4/20 0.38
ALDH1A1 P00352 3/20 0.36
NPSR1 Q6W5P4 3/20 0.36
NPC1 O15118 3/20 0.36
RAB9A P51151 3/20 0.36
KDM4E B2RXH2 2/20 0.36
HPGD P15428 2/20 0.36
POLB P06746 1/20 0.36
MAPT P10636 1/20 0.36
HSD17B10 Q99714 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
TDP1 Q9NUW8 1/20 0.35
PTK2 Q05397 1/20 0.35
LMNA P02545 3/20 0.34
CNR1 P21554 2/20 0.34
GPR55 Q9Y2T6 2/20 0.34
HTT P42858 2/20 0.34
CYP1A2 P05177 1/20 0.34
CYP2D6 P10635 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16482337 0.88 RPS6KA3 (0.41) MEN1KMT2AALDH1A1NPC1RAB9A
SCHEMBL13098376 0.84 AOC3 (0.36) ALDH1A1POLBHTTCYP19A1
SCHEMBL16482132 0.83 MGAT2 (0.52) CYP1A2
SCHEMBL5028258 0.83 CYP19A1 (0.38) ALDH1A1POLBCYP1A2CYP19A1
SCHEMBL16482061 0.82 PRKCI (0.44) HTTELANE
SCHEMBL10018490 0.82 HTT (0.35) MEN1KMT2AMAPTTDP1HTT
SCHEMBL10018491 0.81 HTR7 (0.37) KDM4EPOLBMAPTHTTCYP1A2
SCHEMBL16481983 0.81 AKR1C3 (0.47) MEN1KMT2AALDH1A1KDM4EPOLB
SCHEMBL261829 0.81 MAOA (0.43) KDM4EMAPTHTTCYP1A2CYP2D6
SCHEMBL261774 0.81 MAOA (0.43) KDM4EMAPTHTTCYP1A2CYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180212157-A1 ORGANIC ELECTROLUMINESCENT DEVICE, THIN LUMINOUS FILM, DISPLAY APPARATUS, AND LIGHTING APPARATUS MERCK PERFORMANCE MATERIALS GERMANY GMBH (DE) 2018-07-26 US disclosed
US-9935269-B2 Electroluminescence element Konica Minolta, Inc. (JP) 2018-04-03 US disclosed
US-20160372683-A1 ORGANIC ELECTROLUMINESCENCE ELEMENT, DISPLAY DEVICE, ILLUMINATION DEVICE, AND LIGHT-EMITTING COMPOSITION Konica Minolta, Inc. (JP) 2016-12-22 US disclosed
US-20160372683-A1 ORGANIC ELECTROLUMINESCENCE ELEMENT, DISPLAY DEVICE, ILLUMINATION DEVICE, AND LIGHT-EMITTING COMPOSITION Konica Minolta, Inc. (JP) 2016-12-22 US disclosed
US-20160268516-A1 ORGANIC ELECTROLUMINESCENT ELEMENT, ELECTRONIC DEVICE, LIGHT EMITTING DEVICE, AND LIGHT EMITTING MATERIAL Konica Minolta, Inc. (JP) 2016-09-15 US disclosed
US-20160268516-A1 ORGANIC ELECTROLUMINESCENT ELEMENT, ELECTRONIC DEVICE, LIGHT EMITTING DEVICE, AND LIGHT EMITTING MATERIAL Konica Minolta, Inc. (JP) 2016-09-15 US disclosed
US-20160197282-A1 ORGANIC ELECTROLUMINESCENT ELEMENT, LIGHT EMITTING DEVICE, LIGHTING DEVICE, DISPLAY DEVICE AND ELECTRONIC DEVICE Konica Minolta, Inc. (JP) 2016-07-07 US disclosed
US-20160197282-A1 ORGANIC ELECTROLUMINESCENT ELEMENT, LIGHT EMITTING DEVICE, LIGHTING DEVICE, DISPLAY DEVICE AND ELECTRONIC DEVICE Konica Minolta, Inc. (JP) 2016-07-07 US disclosed
US-20150287927-A1 ELECTROLUMINESCENCE ELEMENT Konica Minolta, Inc. (JP) 2015-10-08 US disclosed
US-20150287927-A1 ELECTROLUMINESCENCE ELEMENT Konica Minolta, Inc. (JP) 2015-10-08 US disclosed
WO-2014057971-A1 ELECTROLUMINESCENCE ELEMENT コニカミノルタ株式会社 (JP) 2014-04-17 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180212157-A1 ORGANIC ELECTROLUMINESCENT DEVICE, THIN LUMINOUS FILM, DISPLAY APPARATUS, AND LIGHTING APPARATUS LPO, L1CAM, EML4 MEN1 3208/4885KMT2A 2230/4885ALDH1A1 340/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.