Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2B | P29275 | 9/20 | 0.72 |
| ▸ | BLM | P54132 | 2/20 | 0.70 |
| ▸ | GLA | P06280 | 1/20 | 0.70 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.69 |
| ▸ | ACHE | P22303 | 2/20 | 0.69 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.69 |
| ▸ | POLB | P06746 | 1/20 | 0.69 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.69 |
| ▸ | CNR1 | P21554 | 1/20 | 0.69 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.69 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.69 |
| ▸ | MC3R | P41968 | 1/20 | 0.69 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.69 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.69 |
| ▸ | GDA | Q9Y2T3 | 1/20 | 0.69 |
| ▸ | NR2E1 | Q9Y466 | 1/20 | 0.69 |
| ▸ | PDE4A | P27815 | 3/20 | 0.63 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.63 |
| ▸ | PDE4C | Q08493 | 3/20 | 0.63 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bisdionin B SCHEMBL29896692 | 0.91 | ADORA2B (0.74) | ADORA2BBLMGLAADORA2AACHE | |
| Bisdionin D SCHEMBL16120988 | 0.88 | ADORA2B (0.79) | ADORA2BBLMGLAADORA2AACHE | |
| Bisdionin C SCHEMBL10018600 | 0.88 | CHIT1 (0.75) | ADORA2BBLMGLAADORA2AACHE | |
| SCHEMBL516446 | 0.88 | ADORA2A (0.74) | ADORA2BBLMGLAADORA2AACHE | |
| SCHEMBL315740 | 0.87 | ADORA2B (0.82) | ADORA2BBLMGLAADORA2AACHE | |
| SCHEMBL5463429 | 0.87 | ADORA2B (0.68) | ADORA2BBLMGLAADORA2AACHE | |
| SCHEMBL29904572 | 0.87 | ADORA2B (0.68) | ADORA2BBLMGLAADORA2AACHE | |
| SCHEMBL7384278 | 0.87 | ADORA2B (0.68) | ADORA2BBLMGLAADORA2AACHE | |
| SCHEMBL6250731 | 0.87 | ADORA2B (0.68) | ADORA2BBLMGLAADORA2AACHE | |
| SCHEMBL29379846 | 0.87 | ADORA2B (0.71) | ADORA2BBLMGLAADORA2AACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4450163-A | ANTIBODY INHIBITORS; N-ALKYLATION OF XANTHINES USING PHASE TRANSFER AGENTS | SOCIETE D'ASSISTANCE TECHNIQUE POUR PRODUITS NESTLE S.A. (CH) | 1984-05-22 | — | — | US | claimed |
| EP-0063827-A1 | 1-Isopropyl- and 1-isobutyl-3,7-dimethyl xanthine as pharmaceutical preparations | SOCIETE DES PRODUITS NESTLE S.A. (CH) | 1982-11-03 | — | — | EP | claimed |
| US-8207175-B2 | Inhibitor compounds | UNIVERSITY COURT OF THE UNIVERSITY OF DUNDEE (GB) | 2012-06-26 | — | — | US | disclosed |
| US-20090215798-A1 | Inhibitor Compounds | UNIVERSITY COURT OF THE UNIVERSITY OF DUNDEE (GB) | 2009-08-27 | — | — | US | disclosed |
| EP-0019165-B1 | PROCESS FOR PREPARING 1,3,7-TRIALKYLXANTHINES | SOCIETE DES PRODUITS NESTLE S.A. (CH) | 1985-07-31 | — | — | EP | disclosed |
| US-4450163-A | ANTIBODY INHIBITORS; N-ALKYLATION OF XANTHINES USING PHASE TRANSFER AGENTS | SOCIETE D'ASSISTANCE TECHNIQUE POUR PRODUITS NESTLE S.A. (CH) | 1984-05-22 | — | — | US | disclosed |
| US-4450163-A | ANTIBODY INHIBITORS; N-ALKYLATION OF XANTHINES USING PHASE TRANSFER AGENTS | SOCIETE D'ASSISTANCE TECHNIQUE POUR PRODUITS NESTLE S.A. (CH) | 1984-05-22 | — | — | US | disclosed |
| US-4450163-A | ANTIBODY INHIBITORS; N-ALKYLATION OF XANTHINES USING PHASE TRANSFER AGENTS | SOCIETE D'ASSISTANCE TECHNIQUE POUR PRODUITS NESTLE S.A. (CH) | 1984-05-22 | — | — | US | disclosed |
| EP-0063827-A1 | 1-Isopropyl- and 1-isobutyl-3,7-dimethyl xanthine as pharmaceutical preparations | SOCIETE DES PRODUITS NESTLE S.A. (CH) | 1982-11-03 | — | — | EP | disclosed |
| EP-0063827-A1 | 1-Isopropyl- and 1-isobutyl-3,7-dimethyl xanthine as pharmaceutical preparations | SOCIETE DES PRODUITS NESTLE S.A. (CH) | 1982-11-03 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090215798-A1 | Inhibitor Compounds | ENGASE, MAN2B2, CHIA | ADORA2B 4138/4885BLM 2841/4885GLA 150/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.