Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 3/20 | 0.56 |
| ▸ | MAOB | P27338 | 10/20 | 0.54 |
| ▸ | MEN1 | O00255 | 3/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | BRD4 | O60885 | 1/20 | 0.52 |
| ▸ | CSNK2A2 | P19784 | 2/20 | 0.49 |
| ▸ | CSNK2B | P67870 | 2/20 | 0.49 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.49 |
| ▸ | MAOA | P21397 | 5/20 | 0.48 |
| ▸ | POLH | Q9Y253 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.48 |
| ▸ | PPARG | P37231 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9928629 | 0.91 | ABCB1 (0.59) | ABCB1MAOBMEN1KMT2AABCG2 | |
| SCHEMBL10018925 | 0.91 | CYP1B1 (0.59) | ABCB1MAOBMEN1KMT2AABCG2 | |
| SCHEMBL10018926 | 0.82 | ABCB1 (0.55) | ABCB1MAOBMEN1KMT2AABCG2 | |
| SCHEMBL9928630 | 0.82 | CYP1B1 (0.71) | ABCB1MAOBMEN1KMT2AABCG2 | |
| SCHEMBL2484718 | 0.81 | MAOB (0.70) | ABCB1MAOBMEN1KMT2AABCG2 | |
| SCHEMBL8859633 | 0.77 | MAOB (0.66) | ABCB1MAOBMEN1KMT2AABCG2 | |
| SCHEMBL7603349 | 0.76 | BRD4 (0.64) | ABCB1MAOBMEN1KMT2AABCG2 | |
| Tetramethylluteolin SCHEMBL29572571 | 0.75 | ABCB1 (0.80) | ABCB1MEN1KMT2AABCG2KDM4E | |
| Tetramethylluteolin SCHEMBL29725288 | 0.75 | ABCB1 (0.80) | ABCB1MEN1KMT2AABCG2KDM4E | |
| Tetramethylluteolin SCHEMBL1421511 | 0.75 | ABCB1 (0.80) | ABCB1MEN1KMT2AABCG2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8203011-B2 | 3′,4′,5-trimethoxy flavone derivatives as stimulant of mucus secretion, method for the same, and pharmaceutical composition comprising the same | DONG-A PHARM. CO., LTD. (KR) | 2012-06-19 | — | — | US | disclosed |
| US-20100130448-A1 | 3',4',5-TRIMETHOXY FLAVONE DERIVATIVES AS STIMULATN OF MUCUS SECRETION, METHOD FOR THE SAME, AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | DONG-A PHARM. CO., LTD (KR) | 2010-05-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100130448-A1 | 3',4',5-TRIMETHOXY FLAVONE DERIVATIVES AS STIMULATN OF MUCUS SECRETION, METHOD FOR THE SAME, AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | TLR5, PTN, TSLP | ABCB1 2160/4885MAOB 3463/4885MEN1 3352/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.