Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1B1 | Q16678 | 6/20 | 0.71 |
| ▸ | CYP1A1 | P04798 | 6/20 | 0.64 |
| ▸ | CYP1A2 | P05177 | 5/20 | 0.64 |
| ▸ | IP6K2 | Q9UHH9 | 3/20 | 0.64 |
| ▸ | ABCC1 | P33527 | 2/20 | 0.64 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.64 |
| ▸ | KDM1A | O60341 | 1/20 | 0.64 |
| ▸ | XDH | P47989 | 1/20 | 0.64 |
| ▸ | IPMK | Q8NFU5 | 1/20 | 0.64 |
| ▸ | MEN1 | O00255 | 3/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.61 |
| ▸ | MAPT | P10636 | 2/20 | 0.61 |
| ▸ | POLB | P06746 | 1/20 | 0.61 |
| ▸ | PLG | P00747 | 1/20 | 0.57 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.57 |
| ▸ | FLT3 | P36888 | 2/20 | 0.57 |
| ▸ | MAOB | P27338 | 2/20 | 0.57 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.57 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10018925 | 0.92 | CYP1B1 (0.59) | CYP1B1CYP1A1CYP1A2IP6K2ABCC1 | |
| SCHEMBL9928629 | 0.90 | ABCB1 (0.59) | CYP1B1CYP1A1CYP1A2IP6K2ABCC1 | |
| SCHEMBL2485248 | 0.90 | CYP1B1 (0.71) | CYP1B1CYP1A1CYP1A2IP6K2ABCC1 | |
| SCHEMBL7306096 | 0.89 | CYP1B1 (0.56) | CYP1B1CYP1A1CYP1A2IP6K2ABCC1 | |
| SCHEMBL28395041 | 0.88 | CYP1A1 (0.61) | CYP1B1CYP1A1CYP1A2IP6K2ABCC1 | |
| SCHEMBL28390996 | 0.86 | CYP1A1 (0.66) | CYP1B1CYP1A1CYP1A2IP6K2ABCC1 | |
| SCHEMBL28396149 | 0.86 | CYP1A1 (0.66) | CYP1B1CYP1A1CYP1A2IP6K2XDH | |
| SCHEMBL29845342 | 0.85 | CYP1B1 (0.86) | CYP1B1CYP1A1CYP1A2IP6K2ABCC1 | |
| SCHEMBL1421382 | 0.85 | CYP1B1 (0.86) | CYP1B1CYP1A1CYP1A2IP6K2ABCC1 | |
| SCHEMBL27907057 | 0.84 | CYP1B1 (0.84) | CYP1B1CYP1A1CYP1A2IP6K2ABCC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8203011-B2 | 3′,4′,5-trimethoxy flavone derivatives as stimulant of mucus secretion, method for the same, and pharmaceutical composition comprising the same | DONG-A PHARM. CO., LTD. (KR) | 2012-06-19 | — | — | US | disclosed |
| US-8203011-B2 | 3′,4′,5-trimethoxy flavone derivatives as stimulant of mucus secretion, method for the same, and pharmaceutical composition comprising the same | DONG-A PHARM. CO., LTD. (KR) | 2012-06-19 | — | — | US | disclosed |
| US-8203011-B2 | 3′,4′,5-trimethoxy flavone derivatives as stimulant of mucus secretion, method for the same, and pharmaceutical composition comprising the same | DONG-A PHARM. CO., LTD. (KR) | 2012-06-19 | — | — | US | disclosed |
| US-20100130448-A1 | 3',4',5-TRIMETHOXY FLAVONE DERIVATIVES AS STIMULATN OF MUCUS SECRETION, METHOD FOR THE SAME, AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | DONG-A PHARM. CO., LTD (KR) | 2010-05-27 | — | — | US | disclosed |
| US-20100130448-A1 | 3',4',5-TRIMETHOXY FLAVONE DERIVATIVES AS STIMULATN OF MUCUS SECRETION, METHOD FOR THE SAME, AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | DONG-A PHARM. CO., LTD (KR) | 2010-05-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100130448-A1 | 3',4',5-TRIMETHOXY FLAVONE DERIVATIVES AS STIMULATN OF MUCUS SECRETION, METHOD FOR THE SAME, AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | TLR5, PTN, TSLP | CYP1B1 2614/4885CYP1A1 2326/4885CYP1A2 2609/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.