SCHEMBL10019948

SCHEMBL10019948

CCOc1ccc(COc2ccc3c(c2F)C(F)C(F)c2c-3ccc(OCC)c2F)cc1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NQO1 P15559 1/20 0.38
MAPT P10636 3/20 0.37
ALDH1A1 P00352 2/20 0.37
LMNA P02545 2/20 0.37
NPC1 O15118 1/20 0.37
RAB9A P51151 1/20 0.37
CYP1A2 P05177 1/20 0.36
CYP2D6 P10635 1/20 0.36
CYP2C19 P33261 1/20 0.36
TDP1 Q9NUW8 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.36
KDM1A O60341 2/20 0.36
TACR2 P21452 1/20 0.35
MEN1 O00255 1/20 0.35
KMT2A Q03164 1/20 0.35
ATM Q13315 1/20 0.35
FFAR1 O14842 1/20 0.35
PPARG P37231 1/20 0.35
PPARD Q03181 1/20 0.35
PPARA Q07869 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10019938 0.88 KDM1A (0.35) MAPTALDH1A1NPC1RAB9ACYP2D6
SCHEMBL10020164 0.85 KDM1A (0.40) LMNAKDM1ATACR2FFAR1PPARG
SCHEMBL10020030 0.85 CACNA1C (0.39) NQO1MAPTALDH1A1LMNACYP1A2
SCHEMBL10019836 0.85 CALM1 (0.36) NQO1CYP1A2CYP2D6CYP2C19TDP1
SCHEMBL10019939 0.83 GAA (0.35) MAPTALDH1A1LMNANPC1RAB9A
SCHEMBL10020156 0.82 CACNA1C (0.39) MAPTALDH1A1LMNATDP1KDM1A
SCHEMBL10020139 0.82 RXRG (0.39) LMNAKDM1AFFAR1PPARGPPARD
SCHEMBL10020029 0.82 FFAR4 (0.35) FFAR1MAOBHCRTR1HCRTR2
SCHEMBL10020133 0.82 PKM (0.34) MAPTALDH1A1L3MBTL1KDM1AMEN1
SCHEMBL10019665 0.82 PKM (0.34) MAPTALDH1A1L3MBTL1KDM1AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2669263-B1 COMPOUND CONTAINING DIHYDROPHENANTHRENE, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE JNC CORP (JP) 2017-11-22 EP disclosed
US-9193908-B2 Compound having dihydrophenanthrene, liquid crystal composition and liquid crystal display device JNC CORPORATION (JP) 2015-11-24 US disclosed
US-9193908-B2 Compound having dihydrophenanthrene, liquid crystal composition and liquid crystal display device JNC CORPORATION (JP) 2015-11-24 US disclosed
US-20130240784-A1 COMPOUND HAVING DIHYDROPHENANTHRENE, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE JNC PETROCHEMICAL CORPORATION (JP) 2013-09-19 US disclosed
US-20130240784-A1 COMPOUND HAVING DIHYDROPHENANTHRENE, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE JNC PETROCHEMICAL CORPORATION (JP) 2013-09-19 US disclosed
WO-2012086437-A1 COMPOUND CONTAINING DIHYDROPHENANTHRENE, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY JNC株式会社 (JP) 2012-06-28 WO disclosed