SCHEMBL10020164

SCHEMBL10020164

CCOc1ccc(COc2ccc3c(c2F)C(F)C(F)c2c-3ccc(OCC)c2F)cc1F

nearest known ligand 0.40

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
KDM1A O60341 4/20 0.40
FFAR1 O14842 5/20 0.39
PPARD Q03181 4/20 0.39
PPARG P37231 1/20 0.39
PPARA Q07869 1/20 0.39
S1PR5 Q9H228 3/20 0.38
S1PR1 P21453 2/20 0.38
LMNA P02545 1/20 0.38
HTT P42858 1/20 0.38
MRGPRX4 Q96LA9 2/20 0.36
HCRTR1 O43613 1/20 0.35
HCRTR2 O43614 1/20 0.35
HTR6 P50406 1/20 0.35
NAAA Q02083 1/20 0.35
TACR2 P21452 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10020139 0.88 RXRG (0.39) KDM1AFFAR1PPARDPPARGPPARA
SCHEMBL10020020 0.86 GABRA1 (0.36) KDM1AS1PR5S1PR1HCRTR1HCRTR2
SCHEMBL10019948 0.85 NQO1 (0.38) KDM1AFFAR1PPARDPPARGPPARA
SCHEMBL10020046 0.85 CALM1 (0.38) KDM1AHCRTR1HCRTR2NAAA
SCHEMBL10019938 0.84 KDM1A (0.35) KDM1AFFAR1TACR2
SCHEMBL10020161 0.83 RXRG (0.36) FFAR1PPARDPPARGPPARALMNA
SCHEMBL10020154 0.83 GABRA1 (0.38) S1PR5S1PR1LMNAHTTNAAA
SCHEMBL10020005 0.82 PKM (0.33) KDM1AFFAR1PPARDPPARGPPARA
SCHEMBL10020016 0.82 CACNA1C (0.38) KDM1AFFAR1PPARDPPARGPPARA
SCHEMBL17490328 0.82 FFAR1 (0.44) KDM1AFFAR1PPARDPPARGPPARA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2669263-B1 COMPOUND CONTAINING DIHYDROPHENANTHRENE, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE JNC CORP (JP) 2017-11-22 EP disclosed
US-9193908-B2 Compound having dihydrophenanthrene, liquid crystal composition and liquid crystal display device JNC CORPORATION (JP) 2015-11-24 US disclosed
US-9193908-B2 Compound having dihydrophenanthrene, liquid crystal composition and liquid crystal display device JNC CORPORATION (JP) 2015-11-24 US disclosed
US-20130240784-A1 COMPOUND HAVING DIHYDROPHENANTHRENE, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE JNC PETROCHEMICAL CORPORATION (JP) 2013-09-19 US disclosed
US-20130240784-A1 COMPOUND HAVING DIHYDROPHENANTHRENE, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE JNC PETROCHEMICAL CORPORATION (JP) 2013-09-19 US disclosed
WO-2012086437-A1 COMPOUND CONTAINING DIHYDROPHENANTHRENE, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY JNC株式会社 (JP) 2012-06-28 WO disclosed