Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.33 |
| ▸ | NPC1 | O15118 | 4/20 | 0.32 |
| ▸ | RAB9A | P51151 | 4/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 2/20 | 0.31 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.31 |
| ▸ | CBFB | Q13951 | 2/20 | 0.31 |
| ▸ | HPGD | P15428 | 3/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1101121 | 0.90 | ALDH1A1 (0.36) | MAPTSMN1; SMN2NPC1RAB9AKDM4E | |
| SCHEMBL1100680 | 0.88 | NPC1 (0.37) | MAPTSMN1; SMN2NPC1RAB9AKDM4E | |
| SCHEMBL1100484 | 0.88 | NPC1 (0.38) | MAPTSMN1; SMN2NPC1RAB9AKDM4E | |
| SCHEMBL29823665 | 0.87 | MAPT (0.32) | MAPTSMN1; SMN2NPC1RAB9AKDM4E | |
| SCHEMBL825195 | 0.87 | MAPT (0.32) | MAPTSMN1; SMN2NPC1RAB9AKDM4E | |
| SCHEMBL1100373 | 0.87 | MAPT (0.34) | MAPTSMN1; SMN2NPC1RAB9AKDM4E | |
| SCHEMBL29565119 | 0.85 | CSNK1D (0.36) | MAPTNPC1RAB9ALMNA | |
| SCHEMBL825192 | 0.85 | CSNK1D (0.36) | MAPTNPC1RAB9ALMNA | |
| SCHEMBL29153159 | 0.79 | TDP1 (0.33) | KDM4EALDH1A1TDP1L3MBTL1 | |
| SCHEMBL10020869 | 0.78 | NPC1 (0.42) | MAPTSMN1; SMN2NPC1RAB9AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8232326-B2 | UV/visible light absorbers for ophthalmic lens materials | NOVARTIS AG (CH) | 2012-07-31 | — | — | US | disclosed |
| US-20120142877-A1 | UV/VISIBLE LIGHT ABSORBERS FOR OPHTHALMIC LENS MATERIALS | NOVARTIS AG (CH) | 2012-06-07 | — | — | US | disclosed |