SCHEMBL1002097

SCHEMBL1002097

CCC(=O)OCC(C)(CO)CO

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.41
HSD17B10 Q99714 1/20 0.41
NAAA Q02083 1/20 0.39
ALDH1A1 P00352 3/20 0.35
CYP1A2 P05177 1/20 0.35
HPGD P15428 1/20 0.35
CYP2C19 P33261 1/20 0.35
BLM P54132 1/20 0.35
WRN Q14191 1/20 0.35
HIF1A Q16665 1/20 0.35
GAA P10253 2/20 0.32
MGAM O43451 1/20 0.32
SI P14410 1/20 0.32
MGAM2 Q2M2H8 1/20 0.32
SOAT1 P35610 1/20 0.32
TSHR P16473 2/20 0.31
CYP3A4 P08684 1/20 0.31
NFKB1 P19838 1/20 0.31
ADRA1A P35348 1/20 0.31
RAB9A P51151 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15281013 0.88 LMNA (0.45) LMNAHSD17B10NAAAALDH1A1CYP1A2
SCHEMBL13771559 0.84 LMNA (0.42) LMNAHSD17B10NAAAALDH1A1CYP1A2
SCHEMBL10399933 0.83 ALDH1A1 (0.44) LMNAHSD17B10ALDH1A1CYP1A2TSHR
SCHEMBL27853451 0.82 NAAA (0.39) LMNAHSD17B10NAAAALDH1A1CYP1A2
SCHEMBL27592335 0.82 NAAA (0.38) LMNAHSD17B10NAAABLMGAA
SCHEMBL14645325 0.80 HSD17B10 (0.41) LMNAHSD17B10TSHR
SCHEMBL20512129 0.80 NAAA (0.38) LMNAHSD17B10NAAAALDH1A1CYP1A2
SCHEMBL18607900 0.80 LMNA (0.39) LMNAHSD17B10NAAAALDH1A1CYP1A2
SCHEMBL17066795 0.79 DGKA (0.47) LMNAHSD17B10ALDH1A1CYP1A2TSHR
SCHEMBL17083541 0.79 ALDH1A1 (0.48) NAAAALDH1A1CYP1A2HPGDCYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102171223-B Sulfur-containing silanes, filled elastomer compositions containing same, and articles made therefrom MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2016-04-20 CN disclosed
EP-2310397-B1 SULFUR-CONTAINING SILANE, FILLED ELASTOMERIC COMPOSITIONS CONTAINING SAME AND ARTICLES MADE THEREFROM MOMENTIVE PERFORMANCE MAT INC (US) 2012-12-12 EP disclosed
CN-102171223-A Sulfur-containing silanes, filled elastomer compositions containing same, and articles made therefrom MOMENTIVE PERFORMANCE MAT INC 2011-08-31 CN disclosed
EP-2310397-A1 SULFUR-CONTAINING SILANE, FILLED ELASTOMERIC COMPOSITIONS CONTAINING SAME AND ARTICLES MADE THEREFROM Momentive Performance Materials Inc. (US) 2011-04-20 EP disclosed
US-20110021692-A1 Sulfur-Containing Silane, Filled Elastomeric Compositions Containing Same And Articles Made Therefrom MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2011-01-27 US disclosed
US-7786200-B2 Sulfur-containing silane, filled elastomeric compositions containing same and articles made therefrom MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2010-08-31 US disclosed
US-20100029817-A1 Sulfur-containing silane, filled elastomeric compositions containing same and articles made therefrom MOMENTIVE PERFORMANCE MATERIALS INC. 2010-02-04 US disclosed
WO-2010014238-A1 SULFUR-CONTAINING SILANE, FILLED ELASTOMERIC COMPOSITIONS CONTAINING SAME AND ARTICLES MADE THEREFROM MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2010-02-04 WO disclosed
US-7645565-B2 Polymerizable composition and lithographic printing plate precursor FUJIFILM CORPORATION (JP) 2010-01-12 US disclosed
US-20090053653-A1 POLYMERIZABLE COMPOSITION AND LITHOGRAPHIC PRINTING PLATE PRECURSOR FUJIFILM CORPORATION (JP) 2009-02-26 US disclosed