SCHEMBL10021047

SCHEMBL10021047

Oc1ccc(C2CCC2)cc1F

nearest known ligand 0.51

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
ACMSD Q8TDX5 2/20 0.51
QDPR P09417 4/20 0.47
ESR2 Q92731 9/20 0.46
HDAC4 P56524 1/20 0.44
HDAC2 Q92769 1/20 0.44
HDAC8 Q9BY41 1/20 0.44
ESR1 P03372 5/20 0.40
CYP3A4 P08684 1/20 0.40
CYP2D6 P10635 1/20 0.40
CYP2C9 P11712 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13072706 0.94 ACMSD (0.57) ACMSDQDPRESR2HDAC4HDAC2
SCHEMBL21630424 0.94 ACMSD (0.57) ACMSDQDPRESR2HDAC4HDAC2
SCHEMBL30215678 0.94 ACMSD (0.57) ACMSDQDPRESR2HDAC4HDAC2
SCHEMBL15729348 0.92 QDPR (0.50) ACMSDQDPRESR2HDAC4HDAC2
SCHEMBL30746608 0.92 QDPR (0.50) ACMSDQDPRESR2HDAC4HDAC2
SCHEMBL7149586 0.85 ESR2 (0.55) ACMSDQDPRESR2HDAC4HDAC2
SCHEMBL7149585 0.85 ESR2 (0.55) ACMSDQDPRESR2HDAC4HDAC2
SCHEMBL21237804 0.83 ESR2 (0.56) ACMSDQDPRESR2ESR1
SCHEMBL21527334 0.83 QDPR (0.71) ACMSDQDPRESR2
SCHEMBL31063246 0.83 QDPR (0.43) ACMSDQDPRESR2ESR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2012020643-A1 COMPOUND HAVING PROPYL ETHER AS BONDING GROUP, LIQUID CRYSTAL COMPOSITION, AND LIQUID CRYSTAL DISPLAY ELEMENT JNC株式会社 (JP) 2012-02-16 WO disclosed