Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 8/20 | 0.55 |
| ▸ | QDPR | P09417 | 5/20 | 0.46 |
| ▸ | ACMSD | Q8TDX5 | 2/20 | 0.41 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.36 |
| ▸ | ESR1 | P03372 | 3/20 | 0.36 |
| ▸ | WDR5 | P61964 | 1/20 | 0.35 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7149585 | 1.00 | ESR2 (0.55) | ESR2QDPRACMSDPDK2ESR1 | |
| SCHEMBL15729348 | 0.92 | QDPR (0.50) | ESR2QDPRACMSDESR1WDR5 | |
| SCHEMBL30746608 | 0.92 | QDPR (0.50) | ESR2QDPRACMSDESR1WDR5 | |
| SCHEMBL10021047 | 0.85 | ACMSD (0.51) | ESR2QDPRACMSDESR1HDAC4 | |
| SCHEMBL14817246 | 0.85 | ESR2 (0.53) | ESR2QDPRPDK2 | |
| SCHEMBL21237804 | 0.84 | ESR2 (0.56) | ESR2QDPRACMSDESR1WDR5 | |
| SCHEMBL21630424 | 0.83 | ACMSD (0.57) | ESR2QDPRACMSDPDK2HDAC4 | |
| SCHEMBL30215678 | 0.83 | ACMSD (0.57) | ESR2QDPRACMSDPDK2HDAC4 | |
| SCHEMBL13072706 | 0.83 | ACMSD (0.57) | ESR2QDPRACMSDPDK2HDAC4 | |
| SCHEMBL19355973 | 0.81 | QDPR (0.73) | ESR2QDPRESR1HDAC4HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0983225-B1 | NEW POLYMERISABLE LIQUID CRYSTALLINE COMPOUNDS | ROLIC AG (CH) | 2003-12-17 | — | — | EP | disclosed |
| US-6395351-B1 | MIXTURE; OPTICS | ROLIC AG (CH) | 2002-05-28 | — | — | US | disclosed |
| EP-0983225-A1 | NEW POLYMERISABLE LIQUID CRYSTALLINE COMPOUNDS | Rolic AG (CH) | 2000-03-08 | — | — | EP | disclosed |
| WO-1998052905-A1 | NEW POLYMERISABLE LIQUID CRYSTALLINE COMPOUNDS | ROLIC AG (CH) | 1998-11-26 | — | — | WO | disclosed |