Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.46 |
| ▸ | PPARA | Q07869 | 2/20 | 0.46 |
| ▸ | CTSS | P25774 | 1/20 | 0.44 |
| ▸ | PPARG | P37231 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.40 |
| ▸ | SYK | P43405 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | KLK7 | P49862 | 1/20 | 0.38 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.38 |
| ▸ | AKT1 | P31749 | 1/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.37 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL210654 | 0.86 | L3MBTL1 (0.50) | NPSR1L3MBTL1PPARACTSSPPARG | |
| SCHEMBL210653 | 0.86 | L3MBTL1 (0.50) | NPSR1L3MBTL1PPARACTSSPPARG | |
| SCHEMBL6859161 | 0.82 | L3MBTL1 (0.50) | NPSR1L3MBTL1PPARACTSSPPARG | |
| SCHEMBL4859584 | 0.78 | NPSR1 (0.47) | NPSR1L3MBTL1PPARACTSSPPARG | |
| SCHEMBL4864100 | 0.78 | NPSR1 (0.48) | NPSR1L3MBTL1PPARACTSSPPARG | |
| SCHEMBL4679985 | 0.74 | SYK (0.47) | L3MBTL1SYK | |
| SCHEMBL1374797 | 0.73 | PPARA (0.52) | NPSR1L3MBTL1PPARACTSSPPARG | |
| SCHEMBL1374794 | 0.73 | PPARA (0.52) | NPSR1L3MBTL1PPARACTSSPPARG | |
| SCHEMBL6318931 | 0.73 | PPARA (0.52) | NPSR1L3MBTL1PPARACTSSPPARG | |
| SCHEMBL6316448 | 0.73 | ATM (0.42) | L3MBTL1CTSSAKT1HDAC3HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7863465-B2 | Antifungal agents | MERCK SHARP & DOHME CORP. (US) | 2011-01-04 | — | — | US | disclosed |
| US-20080009504-A1 | Antifungal agents | SCYNEXIS, INC. | 2008-01-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080009504-A1 | Antifungal agents | DPM1, MAN2B1, MAN2A1 | NPSR1 3994/4885L3MBTL1 3320/4885PPARA 4684/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.