SCHEMBL6318931

SCHEMBL6318931

CN(C(=O)OC(C)(C)C)[C@H](COCc1ccccc1)C(=O)O

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PPARA Q07869 2/20 0.52
NPSR1 Q6W5P4 1/20 0.49
L3MBTL1 Q9Y468 4/20 0.49
PPARG P37231 1/20 0.47
CTSS P25774 1/20 0.46
MMP13 P45452 1/20 0.43
SLC1A1 P43005 1/20 0.43
CA1 P00915 2/20 0.41
RAB9A P51151 1/20 0.41
MAOB P27338 1/20 0.40
KLK7 P49862 1/20 0.39
KLK5 Q9Y337 1/20 0.39
CA2 P00918 1/20 0.39
CA7 P43166 1/20 0.39
CA9 Q16790 1/20 0.39
HDAC3 O15379 1/20 0.39
HDAC1 Q13547 1/20 0.39
HDAC2 Q92769 1/20 0.39
NCOR2 Q9Y618 1/20 0.39
FOLH1 Q04609 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1374794 1.00 PPARA (0.52) PPARANPSR1L3MBTL1PPARGCTSS
SCHEMBL1374797 1.00 PPARA (0.52) PPARANPSR1L3MBTL1PPARGCTSS
SCHEMBL29097329 0.90 PPARA (0.44) PPARANPSR1L3MBTL1PPARGCTSS
SCHEMBL29097327 0.90 PPARA (0.44) PPARANPSR1L3MBTL1PPARGCTSS
SCHEMBL1414518 0.89 PPARA (0.49) PPARANPSR1L3MBTL1PPARGCTSS
SCHEMBL1414516 0.89 PPARA (0.49) PPARANPSR1L3MBTL1PPARGCTSS
Cyclohexylamine SCHEMBL8767343 0.88 L3MBTL1 (0.43) PPARANPSR1L3MBTL1PPARGCTSS
SCHEMBL20721868 0.86 MMP13 (0.43) PPARANPSR1L3MBTL1PPARGCTSS
SCHEMBL6513916 0.85 PPARA (0.50) PPARANPSR1L3MBTL1PPARGCTSS
SCHEMBL1401042 0.83 MMP13 (0.46) L3MBTL1CTSSMMP13

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025235719-A1 DIMERIC SMAC MIMETICS USEFUL IN HIV THERAPY VIIV HEALTHCARE COMPANY (US) 2025-11-13 WO disclosed
US-6939880-B2 Compounds with growth hormone releasing properties NOVO NORDISK A/S (DK) 2005-09-06 US disclosed
US-6555570-B2 Growth hormone secretagogous with improved bioavailability NOVO NORDISK A/S (DE) 2003-04-29 US disclosed
US-20030055261-A1 Compounds with growth hormone releasing properties HELSINN THERAPEUTICS (U.S.), INC. 2003-03-20 US disclosed
US-20030040483-A1 Compounds with growth hormone releasing properties HELSINN THERAPEUTICS (U.S.), INC. 2003-02-27 US disclosed
US-6127391-A A PEPTIDE MIMETIC COMPOUND FOR STIMULATING THE RELEASE OF GROWTH HORMONE FROM THE PITUITARY NOVO NORDISK A/S (DK) 2000-10-03 US disclosed
US-5977178-A Compounds with growth hormone releasing properties NOVO NORDISK A/S (DK) 1999-11-02 US disclosed
CN-1211991-A Compounds with growth hormone releasing properties NOVO NORDISK AS (DK) 1999-03-24 CN disclosed
EP-0869974-A1 COMPOUNDS WITH GROWTH HORMONE RELEASING PROPERTIES NOVO NORDISK A/S (DK) 1998-10-14 EP disclosed
WO-1997023508-A1 COMPOUNDS WITH GROWTH HORMONE RELEASING PROPERTIES NOVO NORDISK A/S (DK) 1997-07-03 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030055261-A1 Compounds with growth hormone releasing properties GHRHR, GHSR, IGFBP1 PPARA 942/4885NPSR1 190/4885L3MBTL1 1220/4885
US-20030040483-A1 Compounds with growth hormone releasing properties GHRHR, GHSR, GRPR PPARA 829/4885NPSR1 191/4885L3MBTL1 1103/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.