Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR1 | P32246 | 1/20 | 0.38 |
| ▸ | CCR5 | P51681 | 1/20 | 0.38 |
| ▸ | CCR8 | P51685 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.35 |
| ▸ | RELA | Q04206 | 1/20 | 0.35 |
| ▸ | AR | P10275 | 1/20 | 0.33 |
| ▸ | CCR6 | P51684 | 1/20 | 0.33 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24066438 | 0.81 | CCR1 (0.60) | CCR1CCR5CCR8HDAC6MEN1 | |
| SCHEMBL10033050 | 0.75 | OXTR (0.41) | TLR8 | |
| SCHEMBL10021965 | 0.75 | CCR1 (0.38) | CCR1CCR5CCR8HDAC6 | |
| SCHEMBL14988155 | 0.75 | ALDH1A1 (0.44) | CCR1CCR5CCR8HDAC6MEN1 | |
| SCHEMBL24118192 | 0.72 | CCR1 (0.41) | CCR1CCR5CCR8HDAC6MEN1 | |
| SCHEMBL18752609 | 0.71 | KDM4E (0.41) | CCR1CCR5CCR8HDAC6MEN1 | |
| SCHEMBL4401757 | 0.70 | CCR1 (0.50) | CCR1CCR5CCR8HDAC6MEN1 | |
| SCHEMBL6256951 | 0.70 | P4HA1 (0.58) | MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL5924747 | 0.70 | MEN1 (0.39) | CCR1CCR5CCR8HDAC6MEN1 | |
| SCHEMBL5924750 | 0.70 | SMN1; SMN2 (0.43) | CCR1CCR5CCR8HDAC6MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012043891-A1 | AGENT FOR TREATMENT OF EYE DISEASES | ダイトーケミックス株式会社 (JP) | 2012-04-05 | — | — | WO | disclosed |