Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OXTR | P30559 | 2/20 | 0.41 |
| ▸ | AVPR1A | P37288 | 2/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.37 |
| ▸ | GRM5 | P41594 | 4/20 | 0.35 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.34 |
| ▸ | DHODH | Q02127 | 1/20 | 0.34 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.33 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.33 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.33 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.32 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.32 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.32 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23667868 | 0.79 | CCR1 (0.52) | OXTRAVPR1AKCNH2GRM5TLR8 | |
| SCHEMBL14988385 | 0.76 | TLR8 (0.42) | OXTRAVPR1AKCNH2GRM5TLR8 | |
| SCHEMBL10022205 | 0.75 | CCR1 (0.38) | TLR8 | |
| SCHEMBL10032806 | 0.75 | DHODH (0.43) | OXTRAVPR1AKCNH2GRM5DHODH | |
| SCHEMBL13771123 | 0.74 | CYP1A2 (0.48) | OXTRAVPR1AKCNH2GPBAR1 | |
| SCHEMBL4653904 | 0.72 | P4HA1 (0.54) | OXTRAVPR1ADHODH | |
| SCHEMBL15256071 | 0.71 | OXTR (0.47) | OXTRAVPR1AKCNH2GRM5GRIN1 | |
| SCHEMBL14988454 | 0.71 | HSPB1 (0.48) | OXTRAVPR1A | |
| SCHEMBL29707796 | 0.70 | — | — | |
| SCHEMBL15120316 | 0.70 | MAPT (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012014994-A1 | NAPHTHALENE DERIVATIVE | ダイトーケミックス株式会社 (JP) | 2012-02-02 | — | — | WO | disclosed |