N-Methyl Pyrrolidine (Nmp)

N-Methyl Pyrrolidine (Nmp)

SCHEMBL1002256

CN1CCCC1.c1ccc2c(c1)CCC2

nearest known ligand 0.60

Full drug profile on Sugi Atlas →

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
DRD1 P21728 15/20 0.60
DRD5 P21918 13/20 0.60
DRD4 P21917 13/20 0.60
DRD3 P35462 13/20 0.60
DRD2 P14416 12/20 0.60
MAOA P21397 2/20 0.60
MAOB P27338 2/20 0.60
TSHR P16473 1/20 0.57
CHRM2 P08172 1/20 0.46
HTR1A P08908 1/20 0.46
ADRA2A P08913 1/20 0.46
CHRM1 P11229 1/20 0.46
SLC6A2 P23975 1/20 0.46
SLC6A4 P31645 1/20 0.46
ADRA1A P35348 1/20 0.46
OPRM1 P35372 1/20 0.46
SLC6A3 Q01959 1/20 0.46
KCNH2 Q12809 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14685816 0.89 MAOA (0.72) DRD1DRD5DRD4DRD3DRD2
SCHEMBL7973918 0.88 DRD1 (0.71) DRD1DRD5DRD4DRD3DRD2
SCHEMBL1950767 0.86 MAOA (0.75) DRD1DRD5DRD4DRD3DRD2
SCHEMBL29391320 0.81 DRD1 (0.85) DRD1DRD5DRD4DRD3DRD2
SCHEMBL164206 0.81 DRD1 (0.85) DRD1DRD5DRD4DRD3DRD2
SCHEMBL9662 0.81
SCHEMBL29354295 0.81
SCHEMBL3057782 0.81 TSHR (0.86) DRD1DRD5DRD4DRD3DRD2
SCHEMBL451157 0.81 TSHR (0.86) DRD1DRD5DRD4DRD3DRD2
Iodide SCHEMBL12468173 0.79 DRD1 (0.81) DRD1DRD5DRD4DRD3DRD2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7989323-B2 Doping method ROHM AND HAAS ELECTRONIC MATERIALS LLC (US) 2011-08-02 US disclosed
US-20110003463-A1 DOPING METHOD ROHM AND HAAS ELECTRONIC MATERIALS LLC (US) 2011-01-06 US disclosed