SCHEMBL10023218

SCHEMBL10023218

Cc1ccc(-c2c3ccccc3c(-c3ccc(-c4nc5ccccc5n4-c4ccccc4)cc3)c3ccccc23)cc1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 11/20 0.56
ESR1 P03372 1/20 0.56
ESR2 Q92731 1/20 0.56
MAPK1 P28482 1/20 0.53
HTT P42858 1/20 0.53
LMNA P02545 2/20 0.52
RAB9A P51151 1/20 0.52
NPSR1 Q6W5P4 1/20 0.52
MDM2 Q00987 1/20 0.52
GAA P10253 1/20 0.52
GRIA1 P42261 1/20 0.51
CACNG8 Q8WXS5 1/20 0.51
CACNG2 Q9Y698 1/20 0.51
SIRT2 Q8IXJ6 1/20 0.50
SIRT1 Q96EB6 1/20 0.50
RXFP1 Q9HBX9 1/20 0.49
TP53 P04637 1/20 0.47
MAPT P10636 2/20 0.46
KDM4E B2RXH2 1/20 0.46
GLA P06280 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11954055 1.00 ALDH1A1 (0.56) ALDH1A1ESR1ESR2MAPK1HTT
SCHEMBL11954092 0.96 ESR1 (0.62) ALDH1A1ESR1ESR2MAPK1HTT
SCHEMBL10023662 0.94 MAPK1 (0.53) ALDH1A1ESR1ESR2MAPK1HTT
SCHEMBL11954060 0.94 ESR1 (0.53) ALDH1A1ESR1ESR2MAPK1HTT
SCHEMBL11954059 0.94 ALDH1A1 (0.51) ALDH1A1ESR1ESR2MAPK1HTT
SCHEMBL24812199 0.93 ESR1 (0.64) ALDH1A1ESR1ESR2MAPK1HTT
SCHEMBL29555357 0.93 ESR1 (0.64) ALDH1A1ESR1ESR2MAPK1HTT
SCHEMBL338233 0.93 ESR1 (0.64) ALDH1A1ESR1ESR2MAPK1HTT
SCHEMBL10023110 0.92 ESR1 (0.56) ALDH1A1ESR1ESR2MAPK1HTT
SCHEMBL11954035 0.92 ESR1 (0.56) ALDH1A1ESR1ESR2MAPK1HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9349964-B2 Organic light emitting diode and manufacturing method thereof LG CHEM, LTD. (KR) 2016-05-24 US disclosed
US-9349964-B2 Organic light emitting diode and manufacturing method thereof LG CHEM, LTD. (KR) 2016-05-24 US disclosed
US-8318948-B2 Fluorene derivatives and organic electronic device using the same LG CHEM, LTD. (KR) 2012-11-27 US disclosed
US-8318948-B2 Fluorene derivatives and organic electronic device using the same LG CHEM, LTD. (KR) 2012-11-27 US disclosed
WO-2012087067-A9 ORGANIC LIGHT-EMITTING DEVICE AND METHOD FOR MANUFACTURING SAME 주식회사 엘지화학 (KR) 2012-09-07 WO disclosed
US-20120193612-A1 ORGANIC LIGHT EMITTING DIODE AND MANUFACTURING METHOD THEREOF LG CHEM, LTD. (KR) 2012-08-02 US disclosed
US-20120193612-A1 ORGANIC LIGHT EMITTING DIODE AND MANUFACTURING METHOD THEREOF LG CHEM, LTD. (KR) 2012-08-02 US disclosed
WO-2012087067-A2 ORGANIC LIGHT-EMITTING DEVICE AND METHOD FOR MANUFACTURING SAME 주식회사 엘지화학 (KR) 2012-06-28 WO disclosed
US-8053762-B2 Imidazoquinazoline derivative, process for preparing the same, and organic electronic device using the same LG CHEM, LTD. (KR) 2011-11-08 US disclosed
US-8053762-B2 Imidazoquinazoline derivative, process for preparing the same, and organic electronic device using the same LG CHEM, LTD. (KR) 2011-11-08 US disclosed
US-20100071769-A1 FLUORENE DERIVATIVES AND ORGANIC ELECTRONIC DEVICE USING THE SAME LG CHEM, LTD. (KR) 2010-03-25 US disclosed
US-20100071769-A1 FLUORENE DERIVATIVES AND ORGANIC ELECTRONIC DEVICE USING THE SAME LG CHEM, LTD. (KR) 2010-03-25 US disclosed
WO-2008069586-A1 NEW FLUORENE DERIVATIVES AND ORGANIC ELECTRONIC DEVICE USING THE SAME LG CHEM, LTD. (KR) 2008-06-12 WO disclosed
US-20070131929-A1 Novel imidazoquinazoline derivative, process for preparing the same, and organic electronic device using the same LG CHEM. LTD. (KR) 2007-06-14 US disclosed
US-20070131929-A1 Novel imidazoquinazoline derivative, process for preparing the same, and organic electronic device using the same LG CHEM. LTD. (KR) 2007-06-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100071769-A1 FLUORENE DERIVATIVES AND ORGANIC ELECTRONIC DEVICE USING THE SAME VDAC2, VDAC1, FTO ALDH1A1 779/4885ESR1 82/4885ESR2 429/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.