SCHEMBL338233

SCHEMBL338233

c1ccc(-c2c3ccccc3c(-c3ccc(-c4nc5ccccc5n4-c4ccccc4)cc3)c3ccccc23)cc1

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 1/20 0.64
ESR2 Q92731 1/20 0.64
GRIA1 P42261 1/20 0.55
CACNG8 Q8WXS5 1/20 0.55
CACNG2 Q9Y698 1/20 0.55
HTT P42858 2/20 0.53
MAPK1 P28482 1/20 0.53
KMT2A Q03164 3/20 0.52
MEN1 O00255 2/20 0.52
HSP90AA1 P07900 1/20 0.52
MAPT P10636 1/20 0.52
ALDH1A1 P00352 7/20 0.51
HPGD P15428 2/20 0.51
KDM4E B2RXH2 1/20 0.51
PTGS2 P35354 1/20 0.49
RECQL P46063 1/20 0.49
PRKACA P17612 1/20 0.48
RPS6KB1 P23443 1/20 0.48
GSK3B P49841 1/20 0.48
ROCK1 Q13464 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24812199 1.00 ESR1 (0.64) ESR1ESR2GRIA1CACNG8CACNG2
SCHEMBL29555357 1.00 ESR1 (0.64) ESR1ESR2GRIA1CACNG8CACNG2
SCHEMBL15696439 0.98 ESR1 (0.62) ESR1ESR2GRIA1CACNG8CACNG2
SCHEMBL24812176 0.98 ESR1 (0.62) ESR1ESR2GRIA1CACNG8CACNG2
SCHEMBL1104867 0.97 ESR1 (0.68) ESR1ESR2GRIA1CACNG8CACNG2
SCHEMBL2604851 0.95 ESR1 (0.67) ESR1ESR2GRIA1CACNG8CACNG2
SCHEMBL14363285 0.95 ESR1 (0.67) ESR1ESR2GRIA1CACNG8CACNG2
SCHEMBL25769062 0.95 ESR1 (0.67) ESR1ESR2GRIA1CACNG8CACNG2
SCHEMBL2604831 0.95 ESR1 (0.67) ESR1ESR2GRIA1CACNG8CACNG2
SCHEMBL18999301 0.94 ESR1 (0.58) ESR1ESR2GRIA1CACNG8CACNG2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 123 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12473315-B2 Polycyclic aromatic compound KWANSEI GAKUIN EDUCATIONAL FOUNDATION (JP) 2025-11-18 US disclosed
US-20250081847-A1 POLYCYCLIC AROMATIC COMPOUND KWANSEI GAKUIN EDUCATIONAL FOUNDATION (JP) 2025-03-06 US disclosed
US-12185625-B2 Organic electroluminescence element, display device, and lighting device KWANSEI GAKUIN EDUCATIONAL FOUNDATION (JP) 2024-12-31 US disclosed
US-20240360158-A1 POLYCYCLIC AROMATIC COMPOUND KWANSEI GAKUIN EDUCATIONAL FOUNDATION (JP) 2024-10-31 US disclosed
EP-3960744-B1 CYCLOALKANE-FUSED POLYCYCLIC AROMATIC COMPOUND KWANSEI GAKUIN EDUCATIONAL FOUND (JP) 2024-08-21 EP disclosed
CN-111936505-B Tertiary alkyl-substituted polycyclic aromatic compounds and uses thereof 学校法人关西学院 2024-07-02 CN disclosed
CN-113412265-B Polycyclic aromatic compounds 学校法人关西学院 2024-05-03 CN disclosed
CN-113013366-B Organic electroluminescent element, display device, lighting device, and anthracene compound 学校法人关西学院 2024-03-26 CN disclosed
CN-111527094-B Compound, polymer compound, material for organic element, organic electroluminescent element, display device, and lighting device 学校法人关西学院 2024-03-26 CN disclosed
US-11877506-B2 Polycyclic aromatic compound KWANSEI GAKUIN EDUCATIONAL FOUNDATION (JP) 2024-01-16 US disclosed
US-8097349-B2 Nitrogen containing heterocycle derivative and organic electroluminescent element using the same IDEMITSU KOSAN CO., LTD. (JP) 2012-01-17 US disclosed
US-7851071-B2 2-[4-(10-naphthalene-2-yl-anthracene-9-yl)-phenyl]-1-phenyl-1H-benzimidazole; elevation of luminance and of efficiency in light emission even under low driving voltage IDEMITSU KOSAN CO., LTD. (JP) 2010-12-14 US disclosed
US-20100283043-A1 ORGANIC EL ELEMENT IDEMITSU LOSAN CO., LTD. 2010-11-11 US disclosed
US-20100283043-A1 ORGANIC EL ELEMENT IDEMITSU LOSAN CO., LTD. 2010-11-11 US disclosed
US-20100193773-A1 Nitrogen-containing heterocycle derivative and organic electroluminescent element using the same IDEMITSU KOSAN CO., LTD, (JP) 2010-08-05 US disclosed
EP-2174933-A2 Nitrogen-containing heterocycle derivative and organic electroluminescent element using the same Idemitsu Kosan Co., Ltd. (JP) 2010-04-14 EP disclosed
EP-2174932-A2 Nitrogen-containing heterocycle derivative and organic electroluminescent element using the same Idemitsu Kosan Co., Ltd. (JP) 2010-04-14 EP disclosed
WO-2008069586-A1 NEW FLUORENE DERIVATIVES AND ORGANIC ELECTRONIC DEVICE USING THE SAME LG CHEM, LTD. (KR) 2008-06-12 WO disclosed
US-20060147747-A1 2-[4-(10-naphthalene-2-yl-anthracene-9-yl)-phenyl]-1-phenyl-1H-benzimidazole; elevation of luminance and of efficiency in light emission even under low driving voltage IDEMITSU KOSAN CO., LTD. (JP) 2006-07-06 US disclosed
EP-1602648-A1 NITROGEN-CONTAINING HETEROCYCLE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT ELEMENT USING THE SAME IDEMITSU KOSAN CO., LTD. (JP) 2005-12-07 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240360158-A1 POLYCYCLIC AROMATIC COMPOUND ETV6, EML4, ELOC ESR1 29/4885ESR2 327/4885GRIA1 3149/4885
US-11877506-B2 Polycyclic aromatic compound F11, C1R, RNF31 ESR1 725/4885ESR2 820/4885GRIA1 1288/4885
US-20250081847-A1 POLYCYCLIC AROMATIC COMPOUND PAH, ALK, AOC2 ESR1 105/4885ESR2 264/4885GRIA1 3930/4885
US-12473315-B2 Polycyclic aromatic compound PAH, ALK, AOC2 ESR1 105/4885ESR2 264/4885GRIA1 3930/4885
US-20100193773-A1 Nitrogen-containing heterocycle derivative and organic electroluminescent element using the same NSD1, EED, ERG ESR1 77/4885ESR2 489/4885GRIA1 3205/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.