SCHEMBL10023944

SCHEMBL10023944

CC=Cc1ccc(C(=O)O)s1

nearest known ligand 0.50

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
DAO P14920 6/20 0.50
PKM P14618 1/20 0.46
LIG1 P18858 1/20 0.46
RARB P10826 2/20 0.40
RARG P13631 2/20 0.40
RXRA P19793 2/20 0.40
RXRB P28702 2/20 0.40
RXRG P48443 2/20 0.40
RARA P10276 1/20 0.40
KMT2A Q03164 2/20 0.40
MAPK1 P28482 1/20 0.40
HPGD P15428 1/20 0.40
MEN1 O00255 1/20 0.39
POLB P06746 1/20 0.39
RAB9A P51151 1/20 0.39
KDM4E B2RXH2 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22380001 0.87 DAO (0.52) DAOPKMLIG1RARBRARG
SCHEMBL13699213 0.82 F2 (0.48) DAOKMT2AMAPK1HPGDMEN1
SCHEMBL8435188 0.77 ALOX5 (0.48) DAOKMT2AMAPK1HPGDMEN1
SCHEMBL8437696 0.77 ALOX5 (0.48) DAOKMT2AMAPK1HPGDMEN1
SCHEMBL8435184 0.77 ALOX5 (0.48) DAOKMT2AMAPK1HPGDMEN1
SCHEMBL209887 0.77 DAO (0.50) DAOPKMLIG1RARBRARG
SCHEMBL6016286 0.77 CA12 (0.45) DAOPKMLIG1KMT2AMAPK1
SCHEMBL6016287 0.77 CA12 (0.45) DAOPKMLIG1KMT2AMAPK1
SCHEMBL16057270 0.76 DAO (0.46) DAOPKMLIG1RARBRARG
SCHEMBL28894342 0.76 DAO (0.46) DAOPKMLIG1RARBRARG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8124777-B2 Compound, photoelectric converter and photoelectrochemical cell SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2012-02-28 US disclosed
US-20100180949-A1 COMPOUND, PHOTOELECTRIC CONVERTER AND PHOTOELECTROCHEMICAL CELL SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2010-07-22 US disclosed
US-20100101650-A1 COMPOUND, PHOTOELECTRIC CONVERSION DEVICE AND PHOTOELECTROCHEMICAL BATTERY SUMITOMO CHEMICAL COMPANY ,LIMITED (JP) 2010-04-29 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100180949-A1 COMPOUND, PHOTOELECTRIC CONVERTER AND PHOTOELECTROCHEMICAL CELL CRY1, CCNE2, DNER DAO 2145/4885PKM 2708/4885LIG1 3769/4885
US-20100101650-A1 COMPOUND, PHOTOELECTRIC CONVERSION DEVICE AND PHOTOELECTROCHEMICAL BATTERY SCO2, C1S, SELENOI DAO 1072/4885PKM 3694/4885LIG1 2680/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.