SCHEMBL209887

SCHEMBL209887

O=Cc1ccc(C(=O)O)s1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DAO P14920 6/20 0.50
PKM P14618 1/20 0.45
LIG1 P18858 1/20 0.45
MEN1 O00255 1/20 0.42
POLB P06746 1/20 0.42
RAB9A P51151 1/20 0.42
KMT2A Q03164 1/20 0.42
RARB P10826 2/20 0.40
RARG P13631 2/20 0.40
RXRA P19793 2/20 0.40
RXRB P28702 2/20 0.40
RXRG P48443 2/20 0.40
RARA P10276 1/20 0.40
KDM4E B2RXH2 2/20 0.39
ALDH1A1 P00352 1/20 0.39
GAA P10253 1/20 0.39
HPGD P15428 1/20 0.39
HDAC3 O15379 1/20 0.39
HDAC4 P56524 1/20 0.39
HDAC1 Q13547 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29957199 0.88 MEN1 (0.50) DAOMEN1POLBRAB9AKMT2A
SCHEMBL6559263 0.87 NPSR1 (0.49) DAOPKMLIG1POLBRARB
SCHEMBL3495814 0.86 DAO (0.43) DAOPKMLIG1RAB9ARARB
SCHEMBL22380001 0.84 DAO (0.52) DAOPKMLIG1MEN1POLB
SCHEMBL8429397 0.80 F2 (0.54) DAOMEN1KMT2AALDH1A1ERN1
SCHEMBL21234794 0.80 ALDH1A1 (0.36) DAOALDH1A1HPGD
SCHEMBL9074074 0.80 DAO (0.48) DAOPKMLIG1MEN1POLB
SCHEMBL6211353 0.80 LMNA (0.48) DAORAB9AKDM4EALDH1A1GAA
SCHEMBL2226671 0.79 NPSR1 (0.53) DAOPKMPOLBRAB9AKMT2A
SCHEMBL7823523 0.79 LMNA (0.40) DAOPKMLIG1ERN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 479 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250327191-A1 CORROSSION INHIBITOR COMPOSITIONS TATA CONSULTANCY SERVICES LIMITED (IN) 2025-10-23 US claimed
EP-4636130-A1 CORROSSION INHIBITOR COMPOSITIONS Tata Consultancy Services Limited (IN) 2025-10-22 EP claimed
CN-116200027-B Flame-retardant nylon and preparation method thereof 浙大宁波理工学院 2024-11-01 CN claimed
CN-111978740-B Solid-phase renewable silicone rubber and preparation method and application thereof 广东工业大学 2022-05-20 CN claimed
CN-113462381-A Polar sensitive NIR probe with high binding force with amyloid fiber and preparation and application thereof 首都师范大学 2021-10-01 CN claimed
CN-111978740-A Solid-phase renewable silicone rubber and preparation method and application thereof 广东工业大学 2020-11-24 CN claimed
US-20110306775-A1 SYNTHESIS AND BIOLOGICAL EVALUATION OF 2',5'-DIMETHOXYCHALCONE DERIVATIVES AS MICROTUBULE-TARGETED ANTICANCER AGENTS KAOHSIUNG MEDICAL UNIVERSITY (TW) 2011-12-15 US claimed
EP-4743175-A1 COMPOUNDS, COMPOSITIONS, AND METHODS Aconcagua Bio, Inc. (US) 2026-05-20 EP disclosed
EP-4743174-A1 MODULATORS OF CALCITONIN RECEPTOR AND/OR AMYLIN RECEPTOR ACTIVITY Aconcagua Bio, Inc. (US) 2026-05-20 EP disclosed
US-20260069602-A1 COMPOUNDS, COMPOSITIONS, AND METHODS ACONCAGUA BIO INC (US) 2026-03-12 US disclosed
US-12503468-B2 Heterocyclic compound, intermediate, preparation method therefor and application thereof WUHAN LL SCIENCE AND TECHNOLOGY DEVELOPMENT CO., LTD. (CN) 2025-12-23 US disclosed
US-12479834-B2 Phenol compound or salt thereof TAIHO PHARMACEUTICAL CO., LTD. (JP) 2025-11-25 US disclosed
US-20250327191-A1 CORROSSION INHIBITOR COMPOSITIONS TATA CONSULTANCY SERVICES LIMITED (IN) 2025-10-23 US disclosed
US-5047554-A 3-substituted-2-oxindole derivatives PFIZER INC. (US) 1991-09-10 US disclosed
EP-0434426-A1 Condensed heterocyclic compounds, their production and use Takeda Chemical Industries, Ltd. (JP) 1991-06-26 EP disclosed
EP-0418924-A2 Pyrrolopyrimidines, their production and use Takeda Chemical Industries, Ltd. (JP) 1991-03-27 EP disclosed
US-4996227-A Administering nontoxic antitumor agents UNIVERSITY OF CINCINNATI (US) 1991-02-26 US disclosed
EP-0393936-A1 3-substituted-2-oxindole derivatives as antiinflammatory agents PFIZER INC. (US) 1990-10-24 EP disclosed
US-4518609-A ANTITUMOR, SKIN DISORDERS SRI INTERNATIONAL (US) 1985-05-21 US disclosed
US-4456618-A ANTITUMOR AGENTS, TREATMENT OF SKIN DISORDERS SRI INTERNATIONAL (US) 1984-06-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12503468-B2 Heterocyclic compound, intermediate, preparation method therefor and application thereof P2RX3, P2RX7, P2RX4 DAO 3298/4885PKM 2394/4885LIG1 3854/4885
US-12479834-B2 Phenol compound or salt thereof REN, MLX, MYB DAO 2265/4885PKM 3542/4885LIG1 2510/4885
US-20110306775-A1 SYNTHESIS AND BIOLOGICAL EVALUATION OF 2',5'-DIMETHOXYCHALCONE DERIVATIVES AS MICROTUBULE-TARGETED ANTICANCER AGENTS TUBB1, TUBB6, TUBA1C DAO 2205/4885PKM 2007/4885LIG1 1153/4885
US-20260069602-A1 COMPOUNDS, COMPOSITIONS, AND METHODS SCTR, SSTR1, NPY1R DAO 2925/4885PKM 4694/4885LIG1 3127/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.