SCHEMBL10024124

SCHEMBL10024124

Cc1ccc(-c2cc(C(C)(C)C)c(O)c(C(C)(C)C)c2)cc1

nearest known ligand 0.71

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
CA2 P00918 4/20 0.71
CA1 P00915 2/20 0.71
SMN1; SMN2 Q16637 2/20 0.61
ALDH1A1 P00352 1/20 0.61
POLB P06746 1/20 0.61
TYR P14679 1/20 0.61
CYP2C9 P11712 2/20 0.61
CYP2C19 P33261 2/20 0.61
CYP1A2 P05177 1/20 0.61
PTGS1 P23219 9/20 0.59
PTGS2 P35354 8/20 0.59
HSPA5 P11021 1/20 0.46
HPN P05981 1/20 0.45
MAPT P10636 1/20 0.45
ALOX15 P16050 1/20 0.45
SIRT5 Q9NXA8 1/20 0.45
HIF1A Q16665 1/20 0.44
ALOX5 P09917 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15445307 1.00 CA2 (0.71) CA2CA1SMN1; SMN2ALDH1A1POLB
SCHEMBL3812524 0.85 CA2 (0.74) CA2CA1SMN1; SMN2ALDH1A1POLB
SCHEMBL27846334 0.85 CA2 (0.74) CA2CA1SMN1; SMN2ALDH1A1POLB
SCHEMBL803157 0.84 CA2 (1.00) CA2CA1SMN1; SMN2ALDH1A1POLB
SCHEMBL13840641 0.83 CA2 (0.71) CA2CA1SMN1; SMN2ALDH1A1POLB
SCHEMBL11350875 0.83 CA2 (0.71) CA2CA1SMN1; SMN2ALDH1A1POLB
SCHEMBL9524225 0.82 CA2 (0.68) CA2CA1SMN1; SMN2ALDH1A1POLB
Butylated Hydroxytoluene SCHEMBL28908240 0.82 CA2 (0.72) CA2CA1SMN1; SMN2ALDH1A1POLB
SCHEMBL11420770 0.82 CA2 (0.68) CA2CA1SMN1; SMN2ALDH1A1POLB
SCHEMBL11426942 0.82 CA2 (0.68) CA2CA1SMN1; SMN2ALDH1A1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12043783-B2 Liquid crystal composition containing benzochromene compound and use thereof SHIJIAZHUANG CHENGZHI YONGHUA DISPLAY MATERIAL CO., LTD. (CN) 2024-07-23 US disclosed
US-12043783-B2 Liquid crystal composition containing benzochromene compound and use thereof SHIJIAZHUANG CHENGZHI YONGHUA DISPLAY MATERIAL CO., LTD. (CN) 2024-07-23 US disclosed
US-20230167363-A1 LIQUID CRYSTAL COMPOSITION CONTAINING BENZOCHROMENE COMPOUND AND USE THEREOF SHIJIAZHUANG CHENGZHI YONGHUA DISPLAY MATERIAL CO.,LTD. (CN) 2023-06-01 US disclosed
US-20230167363-A1 LIQUID CRYSTAL COMPOSITION CONTAINING BENZOCHROMENE COMPOUND AND USE THEREOF SHIJIAZHUANG CHENGZHI YONGHUA DISPLAY MATERIAL CO.,LTD. (CN) 2023-06-01 US disclosed
US-20200208054-A1 LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY ELEMENT DIC Corporation (Tokyo) (JP) 2020-07-02 US disclosed
US-20200172811-A1 LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE DIC CORPORATION (JP) 2020-06-04 US disclosed
US-10633590-B2 Liquid crystal composition and liquid crystal display device including the same DIC CORPORATION (JP) 2020-04-28 US disclosed
US-10465113-B2 Nematic liquid crystal composition, and liquid crystal display element manufactured using same DIC CORPORATION (JP) 2019-11-05 US disclosed
US-10351772-B2 Nematic liquid crystal composition and liquid crystal display element using same DIC CORPORATION (JP) 2019-07-16 US disclosed
US-20190203120-A1 LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE DIC CORPORATION (JP) 2019-07-04 US disclosed
US-9411207-B2 Nematic liquid crystal composition and liquid crystal display element using the same DIC CORPORATION (JP) 2016-08-09 US disclosed
US-20160075947-A1 NEMATIC LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY ELEMENT USING SAME DIC CORPORATION (JP) 2016-03-17 US disclosed
US-20150286081-A1 NEMATIC LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY ELEMENT USING THE SAME DIC CORPORATION (JP) 2015-10-08 US disclosed
US-20150275086-A1 NEMATIC LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE USING SAME DIC CORPORATION (JP) 2015-10-01 US disclosed
US-8206881-B2 Electrophotographic photoreceptor and image forming apparatus SHARP KABUSHIKI KAISHA (JP) 2012-06-26 US disclosed
US-20090129817-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR AND IMAGE FORMING APPARATUS SHARP KABUSHIKI KAISHA (JP) 2009-05-21 US disclosed
US-7534539-B2 Electrophotographic photoreceptor and image forming apparatus having the same SHARP KABUSHIKI KAISHA (JP) 2009-05-19 US disclosed
US-4232043-A HALO-, METHOXY-, METHYL- OR 4-NITRO PHENYL-SUBSTITUTED 2,6-DI(T-BUTYL) PHENOL RIKER LABORATORIES, INC. (US) 1980-11-04 US disclosed
US-4219501-A Anti-inflammatory method RIKER LABORATORIES, INC. (US) 1980-08-26 US disclosed
US-4172151-A 2,6-DI-TERT-BUTYL-PHENOL DERIVATIVES RIKER LABORATORIES, INC. (US) 1979-10-23 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10465113-B2 Nematic liquid crystal composition, and liquid crystal display element manufactured using same LBR, VSIR, KIF23 CA2 3180/4885CA1 2256/4885SMN1; SMN2 2334/4885
US-10633590-B2 Liquid crystal composition and liquid crystal display device including the same LASP1, UACA, CCDC22 CA2 3144/4885CA1 1150/4885SMN1; SMN2 3129/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.