Isopropamide

Isopropamide

SCHEMBL100255

CC(C)[N+](C)(CCC(C(N)=O)(c1ccccc1)c1ccccc1)C(C)C.[I-]

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

CHRM1CHRM3

The experimentally established mechanism targets of Isopropamide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CHRM3 known ✓ P20309 7/20 0.97
CHRM1 known ✓ P11229 1/20 0.97
KDM4E B2RXH2 1/20 1.00
CTDSP1 Q9GZU7 1/20 1.00
CHRM2 P08172 4/20 0.97
KCNH2 Q12809 3/20 0.97
CYP2D6 P10635 2/20 0.97
LMNA P02545 1/20 0.97
OPRK1 P41145 2/20 0.44
SLC22A2 O15244 1/20 0.44
SLC22A1 O15245 1/20 0.44
PGR P06401 1/20 0.44
THRB P10828 1/20 0.44
ADRB3 P13945 1/20 0.44
BLM P54132 1/20 0.44
PMP22 Q01453 1/20 0.44
PDE3A Q14432 1/20 0.44
SLC47A1 Q96FL8 1/20 0.44
CYP3A4 P08684 1/20 0.44
ALOX15 P16050 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Isopropamide SCHEMBL100256 0.98 CHRM3 (1.00) KDM4ECTDSP1CHRM3CHRM2KCNH2
Isopropamide SCHEMBL3082703 0.97 CHRM3 (0.97) KDM4ECTDSP1CHRM3CHRM2KCNH2
Isopropamide SCHEMBL14672609 0.96 CHRM3 (0.94) KDM4ECTDSP1CHRM3CHRM2KCNH2
Isopropamide SCHEMBL7796559 0.91 CHRM3 (0.85) KDM4ECTDSP1CHRM3CHRM2KCNH2
Isopropamide SCHEMBL17923572 0.89 KDM4E (0.79) KDM4ECTDSP1CHRM3CHRM2KCNH2
SCHEMBL4538265 0.88 CHRM3 (0.80) KDM4ECTDSP1CHRM3CHRM2KCNH2
Ambutonium SCHEMBL11946672 0.79 CHRM3 (0.67) KDM4ECTDSP1CHRM3CHRM2KCNH2
Ambutonium SCHEMBL249674 0.78 CHRM3 (0.65) KDM4ECTDSP1CHRM3CHRM2KCNH2
SCHEMBL25341236 0.76 CHRM3 (0.63) KDM4ECTDSP1CHRM3CHRM2KCNH2
Hydrochloric Acid SCHEMBL30307081 0.75 CHRM3 (0.61) KDM4ECTDSP1CHRM3CHRM2KCNH2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2682 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250144193-A1 PROBIOTIC VACCINES AND RELATED METHODS OF USE SALVITUS, INC. 2025-05-08 US claimed
EP-4536236-A2 METHODS OF MODULATING ATXN2 EXPRESSION University of Utah Research Foundation (US) 2025-04-16 EP claimed
EP-4479539-A2 PROBIOTIC VACCINES AND RELATED METHODS OF USE Salvitus, Inc. (US) 2024-12-25 EP claimed
WO-2024178160-A2 RECOMBINANT PHAGE, PROBIOTIC VACCINES AND THERAPEUTICS, RELATED COMPOSITIONS AND METHODS OF USE SALVITUS, INC. (US) 2024-08-29 WO claimed
WO-2023239747-A2 METHODS OF MODULATING ATXN2 EXPRESSION UNIVERSITY OF UTAH RESEARCH FOUNDATION (US) 2023-12-14 WO claimed
WO-2023158883-A2 PROBIOTIC VACCINES AND RELATED METHODS OF USE SALVITUS, INC. (US) 2023-08-24 WO claimed
CN-110751189-B Ellipse detection method based on perception contrast and feature selection 北京航空航天大学 2022-02-22 CN claimed
US-20220008334-A1 GASTRIC RETENTIVE DEVICES CLEXIO BIOSCIENCES LTD. (IL) 2022-01-13 US claimed
US-11147766-B2 Gastric retentive devices CLEXIO BIOSCIENCES LTD. (IL) 2021-10-19 US claimed
US-20200187851-A1 PERIODONTAL DISEASE STRATIFICATION AND USES THEREOF THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL 2020-06-18 US claimed
CN-1520818-A Cholinesterase inhibitor pharmaceutical composition for senile dementia ɽ����Ҷ��Ȼҩ���о��������޹�˾ 2004-08-18 CN claimed
WO-2004041263-A1 NEW PHARMACEUTICAL COMPOSITIONS CONTAINING AMBROXOL AND ISOPROPAMIDE IODIDE BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2004-05-21 WO claimed
EP-1417961-A1 New pharmaceutical compositions containing a combination of ambroxol or bromhexine and isopropamide iodide Boehringer Ingelheim International GmbH (DE) 2004-05-12 EP claimed
WO-2003089012-A2 CAVITY FILLING BIOPSY SITE MARKER SENORX, INC. (US) 2003-10-30 WO claimed
EP-1305355-A1 HYDROGEL FILMS AND METHODS OF MAKING AND USING THEREFOR The University of Utah Research Foundation (US) 2003-05-02 EP claimed
EP-1273301-A2 Pharmaceutical preparations based on active ingredients susceptible to illicit administration ALTERGON S.A. (CH) 2003-01-08 EP claimed
US-20020188196-A1 Cavity-filling biopsy site markers SENORX, INC. 2002-12-12 US claimed
WO-2002006373-A1 HYDROGEL FILMS AND METHODS OF MAKING AND USING THEREFOR UNIVERSITY OF UTAH RESEARCH FOUNDATION (US) 2002-01-24 WO claimed
US-5023088-A Drug delivery dispenser ALZA CORPORATION (US) 1991-06-11 US claimed
US-4824676-A ANTICHOLINERGIC AGENT TO SUPPRESS PERSPIRATION SCHERING CORPORATION (US) 1989-04-25 US claimed