Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14241656 | 0.92 | MAPT (0.33) | ALDH1A1CACNA1HHPGDMAPT | |
| SCHEMBL24296697 | 0.85 | ALDH1A1 (0.31) | ALDH1A1TSHRCACNA1HRECQLGAA | |
| SCHEMBL21708194 | 0.76 | TERT (0.36) | CACNA1HRECQL | |
| SCHEMBL23185124 | 0.75 | LMNA (0.38) | ALDH1A1TSHRRECQLGAAHPGD | |
| SCHEMBL2839703 | 0.75 | CYP2D6 (0.34) | CACNA1HRECQLGAA | |
| SCHEMBL6036335 | 0.75 | KDM4E (0.36) | ALDH1A1TSHRCACNA1HRECQL | |
| SCHEMBL8070363 | 0.74 | PDE4B (0.33) | CACNA1H | |
| SCHEMBL24296912 | 0.73 | RECQL (0.34) | CACNA1HRECQLGAA | |
| SCHEMBL20158616 | 0.73 | HPGD (0.46) | RECQLHPGD | |
| SCHEMBL20261234 | 0.73 | CACNA1H (0.31) | CACNA1H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230348405-A1 | PSMA-TARGETING COMPOUNDS AND USES THEREOF | THE JOHNS HOPKINS UNIVERSTY | 2023-11-02 | — | — | US | disclosed |
| US-11661402-B2 | PSMA-targeting compounds and uses thereof | THE JOHNS HOPKINS UNIVERSITY (US) | 2023-05-30 | — | — | US | disclosed |
| US-9776977-B2 | PSMA-targeting compounds and uses thereof | THE JOHNS HOPKINS UNIVERSITY (US) | 2017-10-03 | — | — | US | disclosed |
| US-9056841-B2 | PSMA-targeting compounds and uses thereof | THE JOHNS HOPKINS UNIVERSITY (US) | 2015-06-16 | — | — | US | disclosed |
| US-20150104387-A1 | PSMA-TARGETING COMPOUNDS AND USES THEREOF | THE JOHNS HOPKINS UNIVERSITY (US) | 2015-04-16 | — | — | US | disclosed |
| US-20120009121-A1 | PSMA-TARGETING COMPOUNDS AND USES THEREOF | THE JOHNS HOPKINS UNIVERSITY (US) | 2012-01-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120009121-A1 | PSMA-TARGETING COMPOUNDS AND USES THEREOF | FOLH1, KLK3, PSMA2 | ALDH1A1 1909/4885TSHR 3529/4885CACNA1H 3172/4885 |
| US-20230348405-A1 | PSMA-TARGETING COMPOUNDS AND USES THEREOF | KLK3, FOLH1, SPR | ALDH1A1 2762/4885TSHR 1759/4885CACNA1H 3746/4885 |
| US-20150104387-A1 | PSMA-TARGETING COMPOUNDS AND USES THEREOF | FOLH1, KLK3, PSMA2 | ALDH1A1 1909/4885TSHR 3529/4885CACNA1H 3172/4885 |
| US-11661402-B2 | PSMA-targeting compounds and uses thereof | KLK3, FOLH1, SPR | ALDH1A1 2762/4885TSHR 1759/4885CACNA1H 3746/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.