SCHEMBL10027630

SCHEMBL10027630

c1ccc(-c2cccc(-c3cccc(-n4c5ccccc5c5c4ccc4c6ccccc6n(-c6cccc(-n7c8ccccc8c8c7ccc7c9ccccc9n(-c9ccccc9)c78)c6)c45)c3)n2)cc1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ L3MBTL1 Q9Y468 2/20 0.42
▸ KDM4E B2RXH2 1/20 0.42
▸ ATM Q13315 1/20 0.42
▸ KMT2A Q03164 4/20 0.37
▸ MEN1 O00255 3/20 0.37
▸ RAB9A P51151 1/20 0.37
▸ GAA P10253 1/20 0.34
▸ JAK2 O60674 1/20 0.33
▸ JAK3 P52333 1/20 0.33
▸ RXFP1 Q9HBX9 1/20 0.33
▸ IL1R1 P14778 1/20 0.32
▸ MAPT P10636 2/20 0.32
▸ ALDH1A1 P00352 1/20 0.32
▸ HTT P42858 1/20 0.32
▸ GABRG2 P18507 1/20 0.31
▸ GABRB3 P28472 1/20 0.31
▸ GABRA5 P31644 1/20 0.31
▸ GABRA3 P34903 1/20 0.31
▸ PTGS2 P35354 1/20 0.31
▸ ASIC3 Q9UHC3 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10027632 1.00 L3MBTL1 (0.42) L3MBTL1KDM4EATMKMT2AMEN1
SCHEMBL12456525 0.99 L3MBTL1 (0.41) L3MBTL1KDM4EATMKMT2AMEN1
SCHEMBL12456520 0.99 L3MBTL1 (0.41) L3MBTL1KDM4EATMKMT2AMEN1
SCHEMBL12456677 0.99 KDM4E (0.40) L3MBTL1KDM4EATMKMT2AMEN1
SCHEMBL12690897 0.99 L3MBTL1 (0.43) L3MBTL1KDM4EATMKMT2AMEN1
SCHEMBL12691178 0.99 L3MBTL1 (0.43) L3MBTL1KDM4EATMKMT2AMEN1
SCHEMBL12456524 0.98 KDM4E (0.39) L3MBTL1KDM4EATMKMT2AMEN1
SCHEMBL10027534 0.98 L3MBTL1 (0.44) L3MBTL1KDM4EATMKMT2AMEN1
SCHEMBL12691249 0.98 L3MBTL1 (0.41) L3MBTL1KDM4EATMKMT2AMEN1
SCHEMBL12456603 0.97 L3MBTL1 (0.39) L3MBTL1KDM4EATMKMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3176241-A1 ORGANIC LIGHT-EMITTING MATERIAL AND ORGANIC LIGHT-EMITTING ELEMENT Nippon Steel & Sumikin Chemical Co., Ltd. (JP) 2017-06-07 — — EP disclosed
EP-2564438-B1 DEPOSITING PREMIXED MATERIALS UNIVERSAL DISPLAY CORP (US) 2016-10-19 — — EP disclosed
US-9299947-B2 Organic electroluminescent device having an electron- and /or exciton-blocking layer comprising an indolocarbazole compound NIPPON STEEL & SUMIKIN CHEMICAL CO., LTD. (JP) 2016-03-29 — — US disclosed
US-9299947-B2 Organic electroluminescent device having an electron- and /or exciton-blocking layer comprising an indolocarbazole compound NIPPON STEEL & SUMIKIN CHEMICAL CO., LTD. (JP) 2016-03-29 — — US disclosed
US-9290498-B2 Organic electroluminescent device having an electron- and/or exciton-blocking layer comprising an indolocarbazole compound NIPPON STEEL & SUMIKIN CHEMICAL CO., LTD. (JP) 2016-03-22 — — US disclosed
US-9290498-B2 Organic electroluminescent device having an electron- and/or exciton-blocking layer comprising an indolocarbazole compound NIPPON STEEL & SUMIKIN CHEMICAL CO., LTD. (JP) 2016-03-22 — — US disclosed
US-9260433-B2 Organic electroluminescent device NIPPON STEEL & SUMIKIN CHEMICAL CO., LTD. (JP) 2016-02-16 — — US disclosed
US-9260433-B2 Organic electroluminescent device NIPPON STEEL & SUMIKIN CHEMICAL CO., LTD. (JP) 2016-02-16 — — US disclosed
US-20150166886-A1 FLUORESCENCE AND DELAYED FLUORESCENCE-TYPE ORGANIC LIGHT-EMITTING MATERIAL AND ELEMENT KYUSHU UNIVERSITY, NATIONAL UNIVERSITY CORPORATION (JP) 2015-06-18 — — US disclosed
US-20150166886-A1 FLUORESCENCE AND DELAYED FLUORESCENCE-TYPE ORGANIC LIGHT-EMITTING MATERIAL AND ELEMENT KYUSHU UNIVERSITY, NATIONAL UNIVERSITY CORPORATION (JP) 2015-06-18 — — US disclosed
US-20130112952-A1 DEPOSITING PREMIXED MATERIALS NIPPON STEEL CHEMICAL CO., LTD. (JP) 2013-05-09 — — US disclosed
US-20120241732-A1 ORGANIC LIGHT-EMITTING MATERIAL AND ORGANIC LIGHT-EMITTING ELEMENT NIPPON STEEL CHEMICAL & MATERIAL CO., LTD. (JP) 2012-09-27 — — US disclosed
US-20120241732-A1 ORGANIC LIGHT-EMITTING MATERIAL AND ORGANIC LIGHT-EMITTING ELEMENT NIPPON STEEL CHEMICAL & MATERIAL CO., LTD. (JP) 2012-09-27 — — US disclosed
US-20120235133-A1 ORGANIC ELECTROLUMINESCENT DEVICE NIPPON STEEL CHEMICAL & MATERIAL CO., LTD. (JP) 2012-09-20 — — US disclosed
US-20120235133-A1 ORGANIC ELECTROLUMINESCENT DEVICE NIPPON STEEL CHEMICAL & MATERIAL CO., LTD. (JP) 2012-09-20 — — US disclosed
US-20120205640-A1 ORGANIC ELECTROLUMINESCENT DEVICE NIPPON STEEL CHEMICAL & MATERIAL CO., LTD. (JP) 2012-08-16 — — US disclosed
US-20120205640-A1 ORGANIC ELECTROLUMINESCENT DEVICE NIPPON STEEL CHEMICAL & MATERIAL CO., LTD. (JP) 2012-08-16 — — US disclosed
US-20120007070-A1 ORGANIC ELECTROLUMINESCENT DEVICE NIPPON STEEL CHEMICAL & MATERIAL CO., LTD. (JP) 2012-01-12 — — US disclosed
US-20120007070-A1 ORGANIC ELECTROLUMINESCENT DEVICE NIPPON STEEL CHEMICAL & MATERIAL CO., LTD. (JP) 2012-01-12 — — US disclosed
WO-2011136755-A1 DEPOSITING PREMIXED MATERIALS UNIVERSAL DISPLAY CORPORATION (US) 2011-11-03 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130112952-A1 DEPOSITING PREMIXED MATERIALS MCM4, MCM2, MCM5 L3MBTL1 2202/4885KDM4E 2235/4885ATM 2676/4885
US-20150166886-A1 FLUORESCENCE AND DELAYED FLUORESCENCE-TYPE ORGANIC LIGHT-EMITTING MATERIAL AND ELEMENT LEF1, EML4, TEAD1 L3MBTL1 155/4885KDM4E 2765/4885ATM 2146/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

Send feedback