SCHEMBL10819259

SCHEMBL10819259

CCOC(=O)CN1C(=O)c2cccc3c(Cl)ccc(c23)C1=O

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PIN1 Q13526 1/20 0.68
PIN4 Q9Y237 1/20 0.68
ALDH1A1 P00352 7/20 0.65
KDM4E B2RXH2 4/20 0.65
LMNA P02545 1/20 0.65
MAPT P10636 2/20 0.56
HTT P42858 1/20 0.56
HSD17B10 Q99714 1/20 0.56
L3MBTL1 Q9Y468 2/20 0.55
TDP1 Q9NUW8 2/20 0.55
CYP1A2 P05177 1/20 0.55
POLB P06746 1/20 0.55
ERCC1 P07992 1/20 0.55
TSHR P16473 1/20 0.55
ALOX12 P18054 1/20 0.55
FEN1 P39748 1/20 0.55
ERCC4 Q92889 1/20 0.55
HPGD P15428 1/20 0.55
KMT2A Q03164 5/20 0.48
MEN1 O00255 4/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10819260 0.86 ALDH1A1 (0.60) PIN1PIN4ALDH1A1KDM4ELMNA
SCHEMBL442751 0.82 PIN1 (1.00) PIN1PIN4ALDH1A1LMNAMAPT
SCHEMBL9340046 0.81 KDM4E (0.67) ALDH1A1KDM4ELMNAMAPTHTT
SCHEMBL11395567 0.81 PIN1 (0.75) PIN1PIN4ALDH1A1KDM4ELMNA
SCHEMBL10819270 0.81 PIN1 (0.58) PIN1PIN4ALDH1A1KDM4ELMNA
SCHEMBL10027652 0.80 LMNA (0.58) ALDH1A1KDM4ELMNAMAPTHTT
SCHEMBL444334 0.80 PIN1 (0.88) PIN1PIN4ALDH1A1LMNAMAPT
SCHEMBL6347785 0.80 ALDH1A1 (1.00) ALDH1A1KDM4ELMNAMAPTHTT
SCHEMBL30153490 0.80 ALDH1A1 (1.00) ALDH1A1KDM4ELMNAMAPTHTT
SCHEMBL11453331 0.79 ALDH1A1 (0.77) PIN1PIN4ALDH1A1MAPTHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9018377-B2 Hydrogen peroxide sensors based upon photo-induced electron transfer OPTI MEDICAL SYSTEMS (US) 2015-04-28 US disclosed
US-20120183984-A1 HYDROGEN PEROXIDE SENSORS BASED UPON PHOTO-INDUCED ELECTRON TRANSFER OPTI MEDICAL SYSTEMS (US) 2012-07-19 US disclosed
US-20120183984-A1 HYDROGEN PEROXIDE SENSORS BASED UPON PHOTO-INDUCED ELECTRON TRANSFER OPTI MEDICAL SYSTEMS (US) 2012-07-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120183984-A1 HYDROGEN PEROXIDE SENSORS BASED UPON PHOTO-INDUCED ELECTRON TRANSFER SQOR, LPO, GPX4 PIN1 1100/4885PIN4 530/4885ALDH1A1 273/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.