SCHEMBL10027972

SCHEMBL10027972

CCOCOc1cc(C)ccc1NC(=O)C(C)CC

nearest known ligand 0.55

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
▸ KDM4E B2RXH2 3/20 0.55
▸ KMT2A Q03164 2/20 0.55
▸ L3MBTL1 Q9Y468 1/20 0.55
▸ LPAR1 Q92633 6/20 0.44
▸ ALDH1A1 P00352 2/20 0.43
▸ LMNA P02545 2/20 0.43
▸ CYP1A2 P05177 1/20 0.43
▸ CYP2C9 P11712 1/20 0.43
▸ CYP2C19 P33261 1/20 0.43
▸ SMN1; SMN2 Q16637 3/20 0.42
▸ RAB9A P51151 3/20 0.41
▸ MAPT P10636 3/20 0.41
▸ HSD17B10 Q99714 2/20 0.41
▸ MEN1 O00255 1/20 0.40
▸ TP53 P04637 1/20 0.40
▸ HTT P42858 1/20 0.40
▸ NPC1 O15118 1/20 0.39
▸ PKM P14618 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10027973 0.90 KMT2A (0.55) KDM4EKMT2AL3MBTL1ALDH1A1LMNA
SCHEMBL10027955 0.83 KMT2A (0.80) KDM4EKMT2AL3MBTL1ALDH1A1LMNA
SCHEMBL1867906 0.79 CYP1A2 (0.43) KMT2AALDH1A1LMNACYP1A2CYP2C9
SCHEMBL12125127 0.76 KMT2A (0.58) KDM4EKMT2AL3MBTL1ALDH1A1LMNA
SCHEMBL10027974 0.75 KMT2A (0.52) KDM4EKMT2AL3MBTL1ALDH1A1HSD17B10
SCHEMBL12125130 0.73 GAA (0.57) KDM4EKMT2AL3MBTL1ALDH1A1LMNA
SCHEMBL31351354 0.72 KMT2A (1.00) KDM4EKMT2AL3MBTL1ALDH1A1LMNA
SCHEMBL10027968 0.71 KMT2A (0.77) KDM4EKMT2AL3MBTL1ALDH1A1LMNA
SCHEMBL4211599 0.70 TSHR (0.47) KDM4EKMT2AL3MBTL1ALDH1A1LMNA
SCHEMBL10027979 0.69 KDM4E (0.57) KDM4EKMT2AL3MBTL1ALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20120021357-A1 POSITIVE-TYPE PHOTOSENSITIVE INSULATING RESIN COMPOSITION, AND PATTERN FORMING METHOD USING SAME NEC CORPORATION (JP) 2012-01-26 — — US disclosed
US-7939241-B2 (Meth)acrylamide derivative, polymer, chemically amplified photosensitive resin composition, and patterning method NEC CORPORATION (JP) 2011-05-10 — — US disclosed
US-20090068587-A1 (Meth) acrylamide derivative, polymer, chemically amplified photosensitive resin composition, and patterning method NEC CORPORATION (JP) 2009-03-12 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090068587-A1 (Meth) acrylamide derivative, polymer, chemically amplified photosensitive resin composition, and patterning method MMAB, DNMT3A, MAT1A KDM4E 1677/4885KMT2A 185/4885L3MBTL1 3368/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

Send feedback