Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 4/20 | 0.36 |
| ▸ | CYP1A1 | P04798 | 3/20 | 0.36 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | AHR | P35869 | 4/20 | 0.33 |
| ▸ | FYN | P06241 | 2/20 | 0.32 |
| ▸ | MAOA | P21397 | 2/20 | 0.32 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.32 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.32 |
| ▸ | MAPK3 | P27361 | 1/20 | 0.32 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.32 |
| ▸ | PGR | P06401 | 2/20 | 0.32 |
| ▸ | CA12 | O43570 | 3/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10028190 | 0.96 | PGR (0.37) | CYP1A2CYP1A1CYP1B1ALDH1A1HPGD | |
| SCHEMBL10028203 | 0.89 | CYP1A2 (0.39) | CYP1A2CYP1A1ALDH1A1HPGDHSD17B10 | |
| SCHEMBL10028197 | 0.87 | AHR (0.38) | CYP1A2CYP1A1ALDH1A1HPGDHSD17B10 | |
| SCHEMBL29737512 | 0.86 | ALDH1A1 (0.48) | CYP1A2CYP1A1CYP1B1ALDH1A1HPGD | |
| SCHEMBL10028079 | 0.86 | ALDH1A1 (0.48) | CYP1A2CYP1A1CYP1B1ALDH1A1HPGD | |
| SCHEMBL10028085 | 0.86 | ESR1 (0.43) | CYP1A2ALDH1A1HPGDHSD17B10CYP3A4 | |
| SCHEMBL10028087 | 0.85 | PGR (0.46) | CYP1A2CYP1A1ALDH1A1HPGDAHR | |
| SCHEMBL14307843 | 0.83 | CYP11B1 (0.30) | HSD17B10CYP3A4TSHRLMNA | |
| SCHEMBL17304507 | 0.82 | ALDH1A1 (0.36) | CYP1A2CYP1A1CYP1B1ALDH1A1HPGD | |
| SCHEMBL10028191 | 0.81 | NPC1 (0.33) | CYP1A2CYP1A1CYP1B1ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2046915-B1 | NEW MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2015-12-02 | — | — | EP | disclosed |
| US-8114531-B2 | Materials for organic electroluminescent devices | MERCK PATENT GMBH (DE) | 2012-02-14 | — | — | US | disclosed |
| US-8114531-B2 | Materials for organic electroluminescent devices | MERCK PATENT GMBH (DE) | 2012-02-14 | — | — | US | disclosed |
| US-20100013381-A1 | NOVEL MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2010-01-21 | — | — | US | disclosed |
| US-20100013381-A1 | NOVEL MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2010-01-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100013381-A1 | NOVEL MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | L1CAM, SOD1, SLC40A1 | CYP1A2 1150/4885CYP1A1 751/4885CYP1B1 650/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.