SCHEMBL10028243

SCHEMBL10028243

[Li]c1ccc2ccc3oc4cccc5ccc6oc1c2c3-c6c54

nearest known ligand 0.33

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.33
CYP1A1 P04798 1/20 0.33
CYP1A2 P05177 1/20 0.33
CYP3A4 P08684 1/20 0.33
HPGD P15428 1/20 0.33
TSHR P16473 1/20 0.33
CYP1B1 Q16678 1/20 0.33
HSD17B10 Q99714 1/20 0.33
CA12 O43570 1/20 0.30
CA1 P00915 1/20 0.30
CA3 P07451 1/20 0.30
CA4 P22748 1/20 0.30
CA6 P23280 1/20 0.30
CA5A P35218 1/20 0.30
CA7 P43166 1/20 0.30
CA9 Q16790 1/20 0.30
CA13 Q8N1Q1 1/20 0.30
CA14 Q9ULX7 1/20 0.30
CA5B Q9Y2D0 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10028079 0.83 ALDH1A1 (0.48) ALDH1A1CYP1A1CYP1A2CYP3A4HPGD
SCHEMBL29737512 0.83 ALDH1A1 (0.48) ALDH1A1CYP1A1CYP1A2CYP3A4HPGD
SCHEMBL10028186 0.82 ALDH1A1 (0.36) ALDH1A1CYP1A1CYP1A2CYP3A4HPGD
SCHEMBL10028194 0.79 ALDH1A1 (0.34) ALDH1A1CYP1A1CYP1A2CYP3A4HPGD
SCHEMBL10062248 0.79 ALDH1A1 (0.40) ALDH1A1CYP1A1CYP1A2CYP3A4HPGD
SCHEMBL10028241 0.76 KMT2A (0.38) ALDH1A1CYP1A2HPGDTSHRHSD17B10
SCHEMBL10028242 0.76 HSD17B10 (0.34) ALDH1A1CYP1A1CYP1A2CYP3A4HPGD
SCHEMBL10028189 0.71 CYP1A2 (0.36) ALDH1A1CYP1A1CYP1A2CYP3A4HPGD
SCHEMBL10028200 0.71 ALDH1A1 (0.36) ALDH1A1CYP1A1CYP1A2CYP3A4HPGD
SCHEMBL30352822 0.70 ALDH1A1 (0.59) ALDH1A1CYP1A1CYP1A2CYP3A4HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8114531-B2 Materials for organic electroluminescent devices MERCK PATENT GMBH (DE) 2012-02-14 US disclosed
US-8114531-B2 Materials for organic electroluminescent devices MERCK PATENT GMBH (DE) 2012-02-14 US disclosed
US-20100013381-A1 NOVEL MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2010-01-21 US disclosed
US-20100013381-A1 NOVEL MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2010-01-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100013381-A1 NOVEL MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES L1CAM, SOD1, SLC40A1 ALDH1A1 220/4885CYP1A1 751/4885CYP1A2 1150/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.