Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.57 |
| ▸ | CYP11B2 | P19099 | 5/20 | 0.47 |
| ▸ | CYP11B1 | P15538 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.44 |
| ▸ | GRM5 | P41594 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | CA1 | P00915 | 2/20 | 0.39 |
| ▸ | CA2 | P00918 | 2/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA7 | P43166 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.38 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.38 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28098032 | 0.83 | CYP2C19 (0.60) | ATMALDH1A1CA1CA2CA12 | |
| SCHEMBL1439962 | 0.82 | ATM (0.65) | ATMCYP11B2CYP11B1ALDH1A1CYP2A6 | |
| SCHEMBL13326244 | 0.81 | ATM (0.62) | ATMCYP11B2CYP11B1ALDH1A1CYP2A6 | |
| SCHEMBL56951 | 0.80 | ATM (0.77) | ATMCYP11B2CYP11B1ALDH1A1CYP2A6 | |
| SCHEMBL10372910 | 0.78 | ATM (0.59) | ATMCYP11B2CYP11B1ALDH1A1CYP2A6 | |
| Hydrochloric Acid SCHEMBL2298745 | 0.78 | ATM (0.74) | ATMCYP11B2CYP11B1ALDH1A1CYP2A6 | |
| SCHEMBL30890087 | 0.77 | ATM (0.57) | ATMCYP11B2CYP11B1ALDH1A1CYP2A6 | |
| SCHEMBL4209337 | 0.77 | ATM (0.57) | ATMCYP11B2CYP11B1ALDH1A1CYP2A6 | |
| SCHEMBL14805797 | 0.77 | ATM (0.57) | ATMCYP11B2CYP11B1ALDH1A1CYP2A6 | |
| SCHEMBL27871827 | 0.77 | ATM (0.57) | ATMCYP11B2CYP11B1ALDH1A1CYP2A6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8658795-B2 | Pyridinium boronic acid quenchers for use in analyte sensors | GLUMETRICS, INC. (US) | 2014-02-25 | — | — | US | disclosed |
| US-8575156-B2 | Cyclic inhibitors of 11β-hydroxysteroid dehydrogenase 1 | VITAE PHARMACEUTICALS, INC. (US) | 2013-11-05 | — | — | US | disclosed |
| US-8569292-B2 | Cyclic inhibitors of 11β-hydroxysteroid dehydrogenase 1 | VITAE PHARMACEUTICALS, INC. (US) | 2013-10-29 | — | — | US | disclosed |
| US-8487094-B2 | Synthesis of inhibitors of 11β-hydroxysteroid dehydrogenase type 1 | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2013-07-16 | — | — | US | disclosed |
| US-20120208286-A1 | PYRIDINIUM BORONIC ACID QUENCHERS FOR USE IN ANALYTE SENSORS | GLUMETRICS, INC. (US) | 2012-08-16 | — | — | US | disclosed |
| US-8178676-B2 | Pyridinium boronic acid quenchers for use in analyte sensors | GLUMETRICS, INC. (US) | 2012-05-15 | — | — | US | disclosed |
| US-20110269957-A1 | SYNTHESIS OF INHIBITORS OF 11BETA-HYDROXYSTEROID DEHYDROGENASE TYPE 1 | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2011-11-03 | — | — | US | disclosed |
| US-20110263584-A1 | Cyclic Inhibitors Of 11Beta-Hydroxysteroid Dehydrogenase 1 | Vitae Pharmaceuticals, Inc. Boehringer Ingelheim International GmbH | 2011-10-27 | — | — | US | disclosed |
| US-20110171742-A1 | PYRIDINIUM BORONIC ACID QUENCHERS FOR USE IN ANALYTE SENSORS | GLUMETRICS, INC. (US) | 2011-07-14 | — | — | US | disclosed |
| US-7939664-B2 | Pyridinium boronic acid quenchers for use in analyte sensors | GLUMETRICS INC. (US) | 2011-05-10 | — | — | US | disclosed |
| US-20080305009-A1 | PYRIDINIUM BORONIC ACID QUENCHERS FOR USE IN ANALYTE SENSORS | GLUMETRICS INC. (US) | 2008-12-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110263584-A1 | Cyclic Inhibitors Of 11Beta-Hydroxysteroid Dehydrogenase 1 | HSD11B1, HSD17B1, HSD11B2 | ATM 3867/4885CYP11B2 11/4885CYP11B1 5/4885 |
| US-20120208286-A1 | PYRIDINIUM BORONIC ACID QUENCHERS FOR USE IN ANALYTE SENSORS | BLVRB, PDXK, PNPO | ATM 4707/4885CYP11B2 1136/4885CYP11B1 1331/4885 |
| US-20110269957-A1 | SYNTHESIS OF INHIBITORS OF 11BETA-HYDROXYSTEROID DEHYDROGENASE TYPE 1 | HSD11B1, HSD17B1, HSD11B2 | ATM 2322/4885CYP11B2 12/4885CYP11B1 8/4885 |
| US-20080305009-A1 | PYRIDINIUM BORONIC ACID QUENCHERS FOR USE IN ANALYTE SENSORS | BLVRB, PDXK, PNPO | ATM 4707/4885CYP11B2 1136/4885CYP11B1 1331/4885 |
| US-20110171742-A1 | PYRIDINIUM BORONIC ACID QUENCHERS FOR USE IN ANALYTE SENSORS | BLVRB, PDXK, PNPO | ATM 4707/4885CYP11B2 1136/4885CYP11B1 1331/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.