Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.40 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | CHRNA1 | P02708 | 1/20 | 0.38 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.38 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | CASP6 | P55212 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7754488 | 0.86 | CHRNB2 (0.39) | ALDH1A1CHRNB2CHRNA4SMN1; SMN2MAPT | |
| SCHEMBL7671788 | 0.86 | CHRNB2 (0.39) | ALDH1A1CHRNB2CHRNA4SMN1; SMN2MAPT | |
| SCHEMBL7657443 | 0.85 | CHRNB2 (0.38) | ALDH1A1CHRNB2CHRNA4SMN1; SMN2MAPT | |
| SCHEMBL888516 | 0.84 | CHRNB2 (0.38) | ALDH1A1CHRNB2CHRNA4SMN1; SMN2MAPT | |
| Nitenpyram SCHEMBL25788 | 0.84 | SMN1; SMN2 (0.40) | ALDH1A1CHRNB2CHRNA4SMN1; SMN2MAPT | |
| Nitenpyram SCHEMBL13448342 | 0.84 | SMN1; SMN2 (0.40) | ALDH1A1CHRNB2CHRNA4SMN1; SMN2MAPT | |
| Nitenpyram SCHEMBL29388004 | 0.84 | SMN1; SMN2 (0.40) | ALDH1A1CHRNB2CHRNA4SMN1; SMN2MAPT | |
| Nitenpyram SCHEMBL31030931 | 0.84 | SMN1; SMN2 (0.40) | ALDH1A1CHRNB2CHRNA4SMN1; SMN2MAPT | |
| SCHEMBL888515 | 0.84 | CHRNB2 (0.38) | ALDH1A1CHRNB2CHRNA4SMN1; SMN2MAPT | |
| Nitenpyram SCHEMBL25789 | 0.84 | SMN1; SMN2 (0.40) | ALDH1A1CHRNB2CHRNA4SMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8993483-B2 | Combination of active substances with insecticidal properties | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2015-03-31 | — | — | US | disclosed |
| US-8993483-B2 | Combination of active substances with insecticidal properties | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2015-03-31 | — | — | US | disclosed |
| US-20120083491-A1 | Combination of Active Substances with Insecticidal Properties | BAYER CROPSCIENCE AG (DE) | 2012-04-05 | — | — | US | disclosed |
| US-20120083491-A1 | Combination of Active Substances with Insecticidal Properties | BAYER CROPSCIENCE AG (DE) | 2012-04-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120083491-A1 | Combination of Active Substances with Insecticidal Properties | ACHE, CHRM3, CHRNA2 | ALDH1A1 2132/4885CHRNB2 16/4885CHRNA4 7/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.