Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.40 |
| ▸ | APEX1 | P27695 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | BCHE | P06276 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 2/20 | 0.35 |
| ▸ | LTA4H | P09960 | 1/20 | 0.35 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.35 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.35 |
| ▸ | HDAC7 | Q8WUI4 | 3/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.35 |
| ▸ | HDAC10 | Q969S8 | 3/20 | 0.35 |
| ▸ | HDAC11 | Q96DB2 | 3/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10030486 | 0.94 | PAX8 (0.45) | POLBPAX8APEX1HTTTDP1 | |
| SCHEMBL10030483 | 0.87 | PAX8 (0.52) | POLBPAX8APEX1HTTTDP1 | |
| SCHEMBL10030478 | 0.87 | HTT (0.39) | POLBPAX8APEX1HTTTDP1 | |
| SCHEMBL10030479 | 0.81 | RAB9A (0.42) | POLBPAX8APEX1HTTTDP1 | |
| SCHEMBL18960047 | 0.80 | POLB (0.59) | POLBAPEX1HTTTDP1PKM | |
| SCHEMBL9807301 | 0.80 | POLB (0.59) | POLBAPEX1HTTTDP1PKM | |
| SCHEMBL17795875 | 0.77 | THRB (0.58) | PAX8BCHEACHEPKMLTA4H | |
| SCHEMBL25123439 | 0.76 | POLB (0.56) | POLBAPEX1HTTTDP1HDAC3 | |
| SCHEMBL25796434 | 0.76 | POLB (0.56) | POLBAPEX1HTTTDP1HDAC3 | |
| SCHEMBL2360555 | 0.75 | THRB (0.53) | POLBAPEX1HTTTDP1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9012582-B2 | Transparent high-refractive-index resin composition | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2015-04-21 | — | — | US | disclosed |
| US-9012582-B2 | Transparent high-refractive-index resin composition | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2015-04-21 | — | — | US | disclosed |
| US-20120142878-A1 | TRANSPARENT HIGH-REFRACTIVE-INDEX RESIN COMPOSITION | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2012-06-07 | — | — | US | disclosed |
| US-20120142878-A1 | TRANSPARENT HIGH-REFRACTIVE-INDEX RESIN COMPOSITION | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2012-06-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120142878-A1 | TRANSPARENT HIGH-REFRACTIVE-INDEX RESIN COMPOSITION | TERB1, H1-5, RRP15 | POLB 3063/4885PAX8 3367/4885APEX1 2121/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.