Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | APEX1 | P27695 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 3/20 | 0.38 |
| ▸ | PPARG | P37231 | 2/20 | 0.38 |
| ▸ | PPARD | Q03181 | 2/20 | 0.38 |
| ▸ | PPARA | Q07869 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.36 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.36 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.36 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.36 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10030479 | 0.94 | RAB9A (0.42) | HTTMEN1KMT2ATDP1POLB | |
| SCHEMBL10030485 | 0.87 | POLB (0.40) | HTTMEN1KMT2ATDP1POLB | |
| SCHEMBL10030483 | 0.82 | PAX8 (0.52) | HTTMEN1KMT2ATDP1POLB | |
| SCHEMBL2033345 | 0.81 | KDM4E (0.54) | HTTMEN1KMT2ATDP1POLB | |
| SCHEMBL29791122 | 0.81 | KDM4E (0.54) | HTTMEN1KMT2ATDP1POLB | |
| SCHEMBL10030486 | 0.81 | PAX8 (0.45) | HTTTDP1POLBAPEX1MAPK1 | |
| SCHEMBL10030482 | 0.80 | TDP1 (0.43) | HTTMEN1KMT2ATDP1POLB | |
| SCHEMBL25123493 | 0.78 | KDM4E (0.62) | HTTMEN1KMT2ATDP1POLB | |
| SCHEMBL116991 | 0.78 | KDM4E (0.62) | HTTMEN1KMT2ATDP1POLB | |
| SCHEMBL17795868 | 0.77 | THRB (0.55) | HTTMEN1KMT2ATDP1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9012582-B2 | Transparent high-refractive-index resin composition | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2015-04-21 | — | — | US | disclosed |
| US-9012582-B2 | Transparent high-refractive-index resin composition | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2015-04-21 | — | — | US | disclosed |
| US-20120142878-A1 | TRANSPARENT HIGH-REFRACTIVE-INDEX RESIN COMPOSITION | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2012-06-07 | — | — | US | disclosed |
| US-20120142878-A1 | TRANSPARENT HIGH-REFRACTIVE-INDEX RESIN COMPOSITION | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2012-06-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120142878-A1 | TRANSPARENT HIGH-REFRACTIVE-INDEX RESIN COMPOSITION | TERB1, H1-5, RRP15 | HTT 1613/4885MEN1 2639/4885KMT2A 448/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.