Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIK1 | P39086 | 3/20 | 0.50 |
| ▸ | GRIK2 | Q13002 | 2/20 | 0.50 |
| ▸ | HDAC3 | O15379 | 4/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 4/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 4/20 | 0.43 |
| ▸ | FFAR3 | O14843 | 3/20 | 0.43 |
| ▸ | CES2 | O00748 | 1/20 | 0.39 |
| ▸ | CES1 | P23141 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 3/20 | 0.36 |
| ▸ | EP300 | Q09472 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.33 |
| ▸ | ABAT | P80404 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | PPARG | P37231 | 3/20 | 0.32 |
| ▸ | PPARD | Q03181 | 3/20 | 0.32 |
| ▸ | PPARA | Q07869 | 3/20 | 0.32 |
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.32 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9493661 | 1.00 | GRIK1 (0.50) | GRIK1GRIK2HDAC3HDAC1HDAC2 | |
| SCHEMBL691600 | 1.00 | GRIK1 (0.50) | GRIK1GRIK2HDAC3HDAC1HDAC2 | |
| SCHEMBL10408349 | 0.98 | GRIK1 (0.48) | GRIK1GRIK2HDAC3HDAC1HDAC2 | |
| Hydrochloric Acid SCHEMBL9624870 | 0.98 | GRIK1 (0.48) | GRIK1GRIK2HDAC3HDAC1HDAC2 | |
| SCHEMBL10412636 | 0.98 | GRIK1 (0.48) | GRIK1GRIK2HDAC3HDAC1HDAC2 | |
| SCHEMBL10408352 | 0.98 | GRIK1 (0.48) | GRIK1GRIK2HDAC3HDAC1HDAC2 | |
| SCHEMBL4433665 | 0.86 | GRIK1 (0.47) | GRIK1GRIK2CES2CES1TSHR | |
| SCHEMBL7556833 | 0.86 | GRIK1 (0.47) | GRIK1GRIK2CES2CES1TSHR | |
| SCHEMBL285080 | 0.86 | GRIK1 (0.47) | GRIK1GRIK2CES2CES1TSHR | |
| Valproic Acid SCHEMBL5936789 | 0.84 | HDAC1 (0.57) | GRIK1GRIK2HDAC3HDAC1HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 118 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118290312-A | Hydrophobic monomer and preparation method thereof, polymer gel and preparation method and application thereof, and plugging material and application thereof | 中国石油化工股份有限公司 | 2024-07-05 | — | — | CN | claimed |
| CN-107074752-B | Therapeutic use of benzylidene guanidine derivatives for the treatment of protein conformation disorders | 英费列特斯生命科学公司 | 2021-10-26 | — | — | CN | claimed |
| EP-3088955-B1 | RESIST COMPOSITION AND PATTERNING PROCESS | SHINETSU CHEMICAL CO (JP) | 2020-06-03 | — | — | EP | claimed |
| EP-3032333-B1 | SHRINK MATERIAL AND PATTERN FORMING PROCESS | SHINETSU CHEMICAL CO (JP) | 2017-05-24 | — | — | EP | claimed |
| EP-3032332-B1 | SHRINK MATERIAL AND PATTERN FORMING PROCESS | SHINETSU CHEMICAL CO (JP) | 2017-04-05 | — | — | EP | claimed |
| EP-2268614-B1 | METHOD FOR PRODUCING BETA-MERCAPTO CARBOXYLIC ACIDS | SHOWA DENKO KK (JP) | 2013-05-15 | — | — | EP | claimed |
| US-20050267168-A1 | Pentanoic acid derivatives | ONO PHARMACEUTICAL CO., LTD. | 2005-12-01 | — | — | US | claimed |
| US-20030096802-A1 | Pentanoic acid derivatives | ONO PHARMACEUTICAL CO., LTD. | 2003-05-22 | — | — | US | claimed |
| US-6201021-B1 | TREATMENT OF DISEASES INDUCED BY REACTIVE ASTROCYTES | ONO PHARMACEUTICAL CO., LTD. (JP) | 2001-03-13 | — | — | US | claimed |
| EP-0632008-B1 | Pentanoic acid derivatives | ONO PHARMACEUTICAL CO (JP) | 1998-02-04 | — | — | EP | claimed |
| EP-0632008-A1 | Pentanoic acid derivatives | ONO PHARMACEUTICAL CO., LTD. (JP) | 1995-01-04 | — | — | EP | claimed |
| US-5262561-A | Dehydrobromination of ester, saponification, antiepileptic agents | ELF SANOFI (FR) | 1993-11-16 | — | — | US | claimed |
| EP-0250997-B1 | VALPROIC AND (E)-2-VALPROENOIC ACID DERIVATIVES, PROCESSES FOR THE PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITIONS THEREFROM | CHIESI FARMACEUTICI S.p.A. (IT) | 1992-04-15 | — | — | EP | claimed |
| US-4966996-A | Process for the preparation of E-2-propyl-2-pentenoic acid and physiologically compatible salts thereof | Desitin Arznemittel GmbH (DE) | 1990-10-30 | — | — | US | claimed |
| US-4945180-A | Process for the preparation of E-2-propyl-2-pentenoic acid and physiologically compatible salts thereof | DESITIN ARZNEIMITTEL GMBH (DE) | 1990-07-31 | — | — | US | claimed |
| EP-0293753-A2 | Process for preparing E-2-propyl-2-pentenoic acid and its physiologically compatible salts | Desitin Arzneimittel GmbH (DE) | 1988-12-07 | — | — | EP | claimed |
| EP-0293752-A2 | Process for preparing E-2-propyl-2-pentenoic acid and its physiologically compatible salts | Desitin Arzneimittel GmbH (DE) | 1988-12-07 | — | — | EP | claimed |
| EP-0250997-A2 | Valproic and (E)-2-valproenoic acid derivatives, processes for the preparation thereof and pharmaceutical compositions therefrom | CHIESI FARMACEUTICI S.p.A. (IT) | 1988-01-07 | — | — | EP | claimed |
| JP-5117204-A | — | — | None | — | — | JP | disclosed |
| US-3976682-A | ALKYLAMMONIUM ALKYLAMINOALKANOATES, FREEZE-THAW ADDITIVE, CORROSION INHIBITOR, PIGMENT GRINDING | TEXACO INC. (US) | 1976-08-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050267168-A1 | Pentanoic acid derivatives | FFAR3, FFAR1, HCAR3 | GRIK1 53/4885GRIK2 170/4885HDAC3 956/4885 |
| US-20030096802-A1 | Pentanoic acid derivatives | FFAR3, FPR1, FPR3 | GRIK1 20/4885GRIK2 48/4885HDAC3 969/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.