Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIK1 | P39086 | 3/20 | 0.50 |
| ▸ | GRIK2 | Q13002 | 2/20 | 0.50 |
| ▸ | HDAC3 | O15379 | 4/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 4/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 4/20 | 0.43 |
| ▸ | FFAR3 | O14843 | 3/20 | 0.43 |
| ▸ | CES2 | O00748 | 1/20 | 0.39 |
| ▸ | CES1 | P23141 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 3/20 | 0.36 |
| ▸ | EP300 | Q09472 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.33 |
| ▸ | ABAT | P80404 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | PPARG | P37231 | 3/20 | 0.32 |
| ▸ | PPARD | Q03181 | 3/20 | 0.32 |
| ▸ | PPARA | Q07869 | 3/20 | 0.32 |
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.32 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1003142 | 1.00 | GRIK1 (0.50) | GRIK1GRIK2HDAC3HDAC1HDAC2 | |
| SCHEMBL9493661 | 1.00 | GRIK1 (0.50) | GRIK1GRIK2HDAC3HDAC1HDAC2 | |
| SCHEMBL10408349 | 0.98 | GRIK1 (0.48) | GRIK1GRIK2HDAC3HDAC1HDAC2 | |
| Hydrochloric Acid SCHEMBL9624870 | 0.98 | GRIK1 (0.48) | GRIK1GRIK2HDAC3HDAC1HDAC2 | |
| SCHEMBL10412636 | 0.98 | GRIK1 (0.48) | GRIK1GRIK2HDAC3HDAC1HDAC2 | |
| SCHEMBL10408352 | 0.98 | GRIK1 (0.48) | GRIK1GRIK2HDAC3HDAC1HDAC2 | |
| SCHEMBL4433665 | 0.86 | GRIK1 (0.47) | GRIK1GRIK2CES2CES1TSHR | |
| SCHEMBL7556833 | 0.86 | GRIK1 (0.47) | GRIK1GRIK2CES2CES1TSHR | |
| SCHEMBL285080 | 0.86 | GRIK1 (0.47) | GRIK1GRIK2CES2CES1TSHR | |
| Valproic Acid SCHEMBL5936789 | 0.84 | HDAC1 (0.57) | GRIK1GRIK2HDAC3HDAC1HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 145 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118290312-A | Hydrophobic monomer and preparation method thereof, polymer gel and preparation method and application thereof, and plugging material and application thereof | 中国石油化工股份有限公司 | 2024-07-05 | — | — | CN | claimed |
| EP-3368593-B1 | IMPROVED BINDER COMPOSITIONS AND USES THEREOF | KNAUF INSULATION SPRL (BE) | 2023-12-06 | — | — | EP | claimed |
| EP-3390535-B1 | PROCESS FOR PRODUCTION OF POLYOXYMETHYLENE INJECTION MOULDED OBJECTS | SABIC GLOBAL TECHNOLOGIES BV (NL) | 2023-05-24 | — | — | EP | claimed |
| CN-107074752-B | Therapeutic use of benzylidene guanidine derivatives for the treatment of protein conformation disorders | 英费列特斯生命科学公司 | 2021-10-26 | — | — | CN | claimed |
| EP-3088955-B1 | RESIST COMPOSITION AND PATTERNING PROCESS | SHINETSU CHEMICAL CO (JP) | 2020-06-03 | — | — | EP | claimed |
| EP-3032333-B1 | SHRINK MATERIAL AND PATTERN FORMING PROCESS | SHINETSU CHEMICAL CO (JP) | 2017-05-24 | — | — | EP | claimed |
| EP-3032332-B1 | SHRINK MATERIAL AND PATTERN FORMING PROCESS | SHINETSU CHEMICAL CO (JP) | 2017-04-05 | — | — | EP | claimed |
| EP-2268614-B1 | METHOD FOR PRODUCING BETA-MERCAPTO CARBOXYLIC ACIDS | SHOWA DENKO KK (JP) | 2013-05-15 | — | — | EP | claimed |
| EP-2205557-B1 | METHOD FOR PRODUCING BETA-MERCAPTOCARBOXYLIC ACIDS | SHOWA DENKO KK (JP) | 2012-02-29 | — | — | EP | claimed |
| US-20050267168-A1 | Pentanoic acid derivatives | ONO PHARMACEUTICAL CO., LTD. | 2005-12-01 | — | — | US | claimed |
| US-20030096802-A1 | Pentanoic acid derivatives | ONO PHARMACEUTICAL CO., LTD. | 2003-05-22 | — | — | US | claimed |
| US-6201021-B1 | TREATMENT OF DISEASES INDUCED BY REACTIVE ASTROCYTES | ONO PHARMACEUTICAL CO., LTD. (JP) | 2001-03-13 | — | — | US | claimed |
| EP-0632008-B1 | Pentanoic acid derivatives | ONO PHARMACEUTICAL CO (JP) | 1998-02-04 | — | — | EP | claimed |
| EP-0632008-A1 | Pentanoic acid derivatives | ONO PHARMACEUTICAL CO., LTD. (JP) | 1995-01-04 | — | — | EP | claimed |
| US-5262561-A | Dehydrobromination of ester, saponification, antiepileptic agents | ELF SANOFI (FR) | 1993-11-16 | — | — | US | claimed |
| EP-0250997-B1 | VALPROIC AND (E)-2-VALPROENOIC ACID DERIVATIVES, PROCESSES FOR THE PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITIONS THEREFROM | CHIESI FARMACEUTICI S.p.A. (IT) | 1992-04-15 | — | — | EP | claimed |
| US-4966996-A | Process for the preparation of E-2-propyl-2-pentenoic acid and physiologically compatible salts thereof | Desitin Arznemittel GmbH (DE) | 1990-10-30 | — | — | US | claimed |
| US-4945180-A | Process for the preparation of E-2-propyl-2-pentenoic acid and physiologically compatible salts thereof | DESITIN ARZNEIMITTEL GMBH (DE) | 1990-07-31 | — | — | US | claimed |
| EP-0250997-A2 | Valproic and (E)-2-valproenoic acid derivatives, processes for the preparation thereof and pharmaceutical compositions therefrom | CHIESI FARMACEUTICI S.p.A. (IT) | 1988-01-07 | — | — | EP | claimed |
| JP-5117204-A | — | — | None | — | — | JP | disclosed |
| US-20260146159-A1 | Random Copolymer | HighRI Optics, Inc. (US) | 2026-05-28 | — | — | US | disclosed |
| CN-121577789-A | Method for detecting 2-propyl-4-pentenoic acid in anti-epileptic drug valproic acid | 湖南省湘中制药有限公司 | 2026-02-27 | — | — | CN | disclosed |
| US-12552935-B2 | Polydisulfide polymer | HighRI Optics, Inc. (US) | 2026-02-17 | — | — | US | disclosed |
| US-20260021111-A1 | GANAXOLONE FOR USE IN TREATMENT OF STATUS EPILEPTICUS | IMMEDICA PHARMA US INC (US) | 2026-01-22 | — | — | US | disclosed |
| US-12246026-B2 | Ganaxolone for use in treatment of status epilepticus | MARINUS PHARMACEUTICALS, INC. (US) | 2025-03-11 | — | — | US | disclosed |
| US-20240329550-A1 | ELECTROPHOTOGRAPHIC PHOTORECEPTOR, ELECTROPHOTOGRAPHIC PHOTORECEPTOR CARTRIDGE, AND IMAGE-FORMING APPARATUS | MITSUBISHI CHEMICAL CORPORATION (JP) | 2024-10-03 | — | — | US | disclosed |
| CN-118638002-A | Preparation method of sodium valproate toxic metabolite 2-propyl-4-pentenoic acid | 湖南大学 | 2024-09-13 | — | — | CN | disclosed |
| US-20240257973-A1 | DISEASE SPECTRUM CLASSIFICATION | PATIENTSLIKEME LLC (US) | 2024-08-01 | — | — | US | disclosed |
| US-20240228780-A1 | Polydisulfide Polymer | ABEAM TECH INC (US) | 2024-07-11 | — | — | US | disclosed |
| CN-118290609-A | Modified oligomeric chitosan and preparation method thereof, copolymer and preparation method and application thereof, and drilling fluid | 中国石油化工股份有限公司 | 2024-07-05 | — | — | CN | disclosed |
| CN-118290312-A | Hydrophobic monomer and preparation method thereof, polymer gel and preparation method and application thereof, and plugging material and application thereof | 中国石油化工股份有限公司 | 2024-07-05 | — | — | CN | disclosed |
| US-11894139-B1 | Disease spectrum classification | PATIENTSLIKEME LLC (US) | 2024-02-06 | — | — | US | disclosed |
| US-20230405021-A1 | GANAXOLONE FOR USE IN TREATMENT OF STATUS EPILEPTICUS | MARINUS PHARMACEUTICALS, INC. | 2023-12-21 | — | — | US | disclosed |
| EP-4214277-A1 | SULFIDE-CONTAINING STABILIZER SYSTEM FOR THIOL-ENE AND THIOL-YNE COMPOSITIONS | Bruno Bock GmbH (DE) | 2023-07-26 | — | — | EP | disclosed |
| US-11679117-B2 | Ganaxolone for use in treatment of status epilepticus | MARINUS PHARMACEUTICALS, INC. (US) | 2023-06-20 | — | — | US | disclosed |
| CN-115812710-A | Insect repellent composition comprising one or more insect repellent fatty acids having 9 to 21 carbon atoms | 长荣置地有限公司 | 2023-03-21 | — | — | CN | disclosed |
| CN-115594561-A | Hydrophobic crosslinking monomer and preparation method thereof, and polymer blocking agent and preparation method thereof | 中石化石油工程技术服务有限公司（CN） | 2023-01-13 | — | — | CN | disclosed |
| CN-112118739-B | Insect repellent composition comprising one or more insect repellent fatty acids having 9 to 21 carbon atoms | 长荣置地有限公司 | 2023-01-10 | — | — | CN | disclosed |
| US-20220265680-A1 | GANAXOLONE FOR USE IN TREATMENT OF STATUS EPILEPTICUS | IMMEDICA PHARMA US INC. | 2022-08-25 | — | — | US | disclosed |
| CN-114728012-A | Ganaxolone for the treatment of status epilepticus | 马瑞纳斯制药公司 | 2022-07-08 | — | — | CN | disclosed |
| US-20220202831-A1 | GANAXOLONE FOR USE IN TREATMENT OF STATUS EPILEPTICUS | IMMEDICA PHARMA US INC. | 2022-06-30 | — | — | US | disclosed |
| EP-4009982-A1 | GANAXOLONE FOR USE IN TREATMENT OF STATUS EPILEPTICUS | Marinus Pharmaceuticals, Inc. (US) | 2022-06-15 | — | — | EP | disclosed |
| US-11110100-B2 | Ganaxolone for use in treatment of status epilepticus | MARINUS PHARMACEUTICALS, INC. (US) | 2021-09-07 | — | — | US | disclosed |
| US-20210186987-A1 | GANAXOLONE FOR USE IN TREATMENT OF STATUS EPILEPTICUS | IMMEDICA PHARMA US INC. | 2021-06-24 | — | — | US | disclosed |
| WO-2021026124-A1 | GANAXOLONE FOR USE IN TREATMENT OF STATUS EPILEPTICUS | MARINUS PHARMACEUTICALS, INC. (US) | 2021-02-11 | — | — | WO | disclosed |
| CN-112118739-A | Insect repellent composition comprising one or more insect repellent fatty acids having 9 to 21 carbon atoms | 长荣置地有限公司 | 2020-12-22 | — | — | CN | disclosed |
| CN-111826242-A | Cleaning solution, method of cleaning semiconductor substrate, and method of manufacturing semiconductor device | 台湾积体电路制造股份有限公司 | 2020-10-27 | — | — | CN | disclosed |
| EP-2561020-B1 | A COATING COMPOSITION | PPG COATINGS EUROPE BV (NL) | 2019-08-28 | — | — | EP | disclosed |
| US-20180371245-A1 | Polydisulfide Polymer | ABEAM TECH INC (US) | 2018-12-27 | — | — | US | disclosed |
| EP-2561021-B1 | A BINDER FOR A SELF POLISHING ANTIFOULING COATING | PPG COATINGS EUROPE BV (NL) | 2018-10-03 | — | — | EP | disclosed |
| US-9988538-B2 | Binder for a self polishing antifouling coating | PPG COATINGS EUROPE B.V. (NL) | 2018-06-05 | — | — | US | disclosed |
| US-9463173-B2 | Compositions and methods for treating obesity and obesity-related conditions | THE JOHNS HOPKINS UNIVERSITY (US) | 2016-10-11 | — | — | US | disclosed |
| US-9382431-B2 | Coating composition | PPG B.V. (NL) | 2016-07-05 | — | — | US | disclosed |
| EP-2753472-B1 | METHOD FOR INCREASING THE COUNTERFEIT PROTECTION FOR AN ARTICLE | DURST PHOTOTECH DIGITAL TECH (AT) | 2016-01-06 | — | — | EP | disclosed |
| CN-102242146-B | Composition and the method with its generation generate induced pluripotent stem cells | KOREA UNIVERSITY INDUSTRY AND (KR) | 2015-11-25 | — | — | CN | disclosed |
| US-20150250747-A1 | COMPOSITIONS AND METHODS FOR TREATING OBESITY AND OBESITY-RELATED CONDITIONS | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2015-09-10 | — | — | US | disclosed |
| US-20150119346-A1 | GLYCOSYLATED VALPROIC ACID ANALOGS AND USES THEREOF | Chromatin Technologies | 2015-04-30 | — | — | US | disclosed |
| US-8921533-B2 | Glycosylated valproic acid analogs and uses thereof | Chromatin Technologies (US) | 2014-12-30 | — | — | US | disclosed |
| US-8569058-B2 | Nerve regeneration promoters | ONO PHARMACEUTICAL CO., LTD. (JP) | 2013-10-29 | — | — | US | disclosed |
| US-8518700-B2 | Composition for reprogramming somatic cells to generate induced pluripotent stem cells, comprising Bmi1 and low molecular weight substance, and method for generating induced pluripotent stem cells using the same | KOREA UNIVERSITY RESEARCH AND BUSINESS FOUNDATION (KR) | 2013-08-27 | — | — | US | disclosed |
| US-20130102726-A1 | Binder For A Self Polishing Antifouling Coating | PPG COATINGS EUROPE B.V. (NL) | 2013-04-25 | — | — | US | disclosed |
| US-20130090418-A1 | Coating Composition | PPG COATINGS EUROPE B.V. (NL) | 2013-04-11 | — | — | US | disclosed |
| WO-2013033742-A2 | METHOD FOR INCREASING THE COUNTERFEIT PROTECTION FOR AN ARTICLE | DURST PHOTOTECHNIK DIGITAL TECHNOLOGY GMBH (AT) | 2013-03-14 | — | — | WO | disclosed |
| EP-2561021-A1 | A BINDER FOR A SELF POLISHING ANTIFOULING COATING | PPG Coatings Europe B.V. (NL) | 2013-02-27 | — | — | EP | disclosed |
| EP-2561020-A1 | A COATING COMPOSITION | PPG Coatings Europe B.V. (NL) | 2013-02-27 | — | — | EP | disclosed |
| US-20130029924-A1 | GLYCOSYLATED VALPROIC ACID ANALOGS AND USES THEREOF | Chromatin Technologies (US) | 2013-01-31 | — | — | US | disclosed |
| EP-2456433-A2 | METHODS FOR THE PREPARATION AND USE OF AQUEOUS SOLUTIONS OF MAGNESIUM VALPROATE HYDRATE AND L-CARNITINE | Biolink Life Sciences, Inc. (US) | 2012-05-30 | — | — | EP | disclosed |
| EP-2399963-A1 | A coating composition | PPG Coatings Europe B.V. (NL) | 2011-12-28 | — | — | EP | disclosed |
| EP-2386608-A1 | A coating composition | PPG Coatings Europe B.V. (NL) | 2011-11-16 | — | — | EP | disclosed |
| CN-102242146-A | Composition and method for generating induced pluripotent stem cells using the same | UNIV KOREA RES & BUS FOUND | 2011-11-16 | — | — | CN | disclosed |
| US-20110275157-A1 | COMPOSITION FOR REPROGRAMMING SOMATIC CELLS TO GENERATE INDUCED PLURIPOTENT STEM CELLS, COMPRISING Bmi1 AND LOW MOLECULAR WEIGHT SUBSTANCE, AND METHOD FOR GENERATING INDUCED PLURIPOTENT STEM CELLS USING THE SAME | KOREA UNIVERSITY RESEARCH AND BUSINESS FOUNDATION (KR) | 2011-11-10 | — | — | US | disclosed |
| WO-2011131742-A1 | A BINDER FOR A SELF POLISHING ANTIFOULING COATING | PPG COATINGS EUROPE B.V (NL) | 2011-10-27 | — | — | WO | disclosed |
| WO-2011131721-A1 | A COATING COMPOSITION | PPG COATINGS EUROPE B.V (NL) | 2011-10-27 | — | — | WO | disclosed |
| US-8039461-B1 | Physical states of a pharmaceutical drug substance | PISGAH LABORATORIES, INC. (US) | 2011-10-18 | — | — | US | disclosed |
| WO-2011011376-A2 | METHODS FOR THE PREPARATION AND USE OF AQUEOUS SOLUTIONS OF MAGNESIUM VALPROATE HYDRATE AND L-CARNITINE | BIOLINK LIFE SCIENCES, INC. (US) | 2011-01-27 | — | — | WO | disclosed |
| US-20110015267-A1 | METHODS FOR THE PREPARATION AND USE OF AQUEOUS SOLUTIONS OF MAGNESIUM VALPROATE HYDRATE AND L-CARNITINE | BIOLINK LIFE SCIENCES, LLC | 2011-01-20 | — | — | US | disclosed |
| US-7569608-B2 | Pentanoic acid derivatives | ONO PHARMACEUTICAL CO., LTD. (JP) | 2009-08-04 | — | — | US | disclosed |
| US-7569608-B2 | Pentanoic acid derivatives | ONO PHARMACEUTICAL CO., LTD. (JP) | 2009-08-04 | — | — | US | disclosed |
| US-7569609-B2 | Pentanoic acid derivatives | ONO PHARMACEUTICAL CO., LTD. (JP) | 2009-08-04 | — | — | US | disclosed |
| US-7569609-B2 | Pentanoic acid derivatives | ONO PHARMACEUTICAL CO., LTD. (JP) | 2009-08-04 | — | — | US | disclosed |
| US-20070043114-A1 | Nerve regeneration promoters | ONO PHARMACEUTICAL CO., LTD. (JP) | 2007-02-22 | — | — | US | disclosed |
| US-7176240-B2 | Pentanoic acid derivatives | ONO PHARMACEUTICAL CO., LTD. (JP) | 2007-02-13 | — | — | US | disclosed |
| US-7176240-B2 | Pentanoic acid derivatives | ONO PHARMACEUTICAL CO., LTD. (JP) | 2007-02-13 | — | — | US | disclosed |
| US-7135542-B2 | Bidentate ligands for the carbonylation of unsaturated compounds | SHELL OIL COMPANY (US) | 2006-11-14 | — | — | US | disclosed |
| US-20060223888-A1 | Valproic acid analogues and pharmaceutical composition thereof | THE UNIVERSITY OF BRITISH COLUMBIA (CA) | 2006-10-05 | — | — | US | disclosed |
| EP-1685832-A1 | NERVE REGENERATION PROMOTERS | ONO PHARMACEUTICAL CO., LTD. (JP) | 2006-08-02 | — | — | EP | disclosed |
| US-20050267168-A1 | Pentanoic acid derivatives | ONO PHARMACEUTICAL CO., LTD. | 2005-12-01 | — | — | US | disclosed |
| US-20050267167-A1 | Pentanoic acid derivatives | ONO PHARMACEUTICAL CO., LTD. | 2005-12-01 | — | — | US | disclosed |
| US-20050261371-A1 | Pentanoic acid derivatives | ONO PHARMACEUTICAL CO., LTD. | 2005-11-24 | — | — | US | disclosed |
| EP-1444241-B1 | BIDENDATE LIGANDS FOR THE CARBONYLATION OF UNSATURATED COMPOUNDS | SHELL INT RESEARCH (NL) | 2005-10-05 | — | — | EP | disclosed |
| US-20040259724-A1 | Bidentate ligands for the carbonylation of unsaturated compounds | SHELL OIL COMPANY | 2004-12-23 | — | — | US | disclosed |
| EP-1444241-A2 | BIDENDATE LIGANDS FOR THE CARBONYLATION OF UNSATURATED COMPOUNDS | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 2004-08-11 | — | — | EP | disclosed |
| WO-2004054957-A2 | VALPROIC ACID ANALOGUES AND PHARMACEUTICAL COMPOSITIONS THEREOF | THE UNIVERSITY OF BRITISH COLUMBIA (CA) | 2004-07-01 | — | — | WO | disclosed |
| US-20030215859-A1 | DNA shuffling of monooxygenase genes for production of industrial chemicals | MAXYGEN, INC. | 2003-11-20 | — | — | US | disclosed |
| US-6605430-B1 | Genetic engineering to produce library of polynucleotides encoding polypeptides; screening, recovering | MAXYGEN, INC. | 2003-08-12 | — | — | US | disclosed |
| US-20030096802-A1 | Pentanoic acid derivatives | ONO PHARMACEUTICAL CO., LTD. | 2003-05-22 | — | — | US | disclosed |
| WO-2003040159-A2 | BIDENTATE LIGANDS FOR THE CARBONYLATION OF UNSATURATED COMPOUNDS | SHELL INTERNATIONALE RESEARCH MAATSCHAPPIJ B.V. (NL) | 2003-05-15 | — | — | WO | disclosed |
| EP-1227111-A1 | TRIPHENYLBORON-CONTAINING POLYMERS AND USE THEREOF | Yoshitomi Fine Chemicals, Ltd. (JP) | 2002-07-31 | — | — | EP | disclosed |
| EP-1104459-A1 | DNA SHUFFLING OF MONOOXYGENASE GENES FOR PRODUCTION OF INDUSTRIAL CHEMICALS | Maxygen, Inc. (US) | 2001-06-06 | — | — | EP | disclosed |
| US-6201021-B1 | TREATMENT OF DISEASES INDUCED BY REACTIVE ASTROCYTES | ONO PHARMACEUTICAL CO., LTD. (JP) | 2001-03-13 | — | — | US | disclosed |
| WO-2000009682-A1 | DNA SHUFFLING OF MONOOXYGENASE GENES FOR PRODUCTION OF INDUSTRIAL CHEMICALS | MAXYGEN, INC. (US) | 2000-02-24 | — | — | WO | disclosed |
| EP-0659174-B1 | DERIVATIVES OF VALPROIC AND 2-VALPROENOIC ACID AMIDES AND USE AS ANTICONVULSANTS | YISSUM RES DEV CO (IL) | 1999-02-10 | — | — | EP | disclosed |
| US-5786380-A | MODIFIED VALPROIC ACID | NAU, HEINZ (DE) | 1998-07-28 | — | — | US | disclosed |
| EP-0632008-B1 | Pentanoic acid derivatives | ONO PHARMACEUTICAL CO (JP) | 1998-02-04 | — | — | EP | disclosed |
| EP-0778820-A1 | NEUROTROPHIC AND ANTIPROLIFERATIVE COMPOUNDS | AMERICAN BIOGENETIC SCIENCES, INC. (US) | 1997-06-18 | — | — | EP | disclosed |
| EP-0659172-B1 | ANALOGUES OF VPA USED AS ANTI-EPILEPTICA | NAU HEINZ (DE) | 1997-04-02 | — | — | EP | disclosed |
| WO-1997009323-A2 | HEXITOLS AND HEXITOL ESTERS FOR USE AS ANTIEPILEPTICS | DESITIN ARZNEIMITTEL GMBH (DE) | 1997-03-13 | — | — | WO | disclosed |
| US-5585358-A | ANTIEPILEPTIC AGENTS; COGNITION ACTIVATORS; NERVOUS SYSTEM DISORDERS; DYSKINESIA; ANTIISCHEMIC AGENTS | YISSUM RESEARCH DEVELOPMENT CORPORATION OF THE HEBREW UNIVERSITY OF JERUSALEM (IL) | 1996-12-17 | — | — | US | disclosed |
| WO-1996006821-A1 | NEUROTROPHIC AND ANTIPROLIFERATIVE COMPOUNDS | AMERICAN BIOGENETIC SCIENCES, INC. (US) | 1996-03-07 | — | — | WO | disclosed |
| EP-0659174-A4 | DERIVATIVES OF VALPROIC AND 2-VALPROENOIC ACID AMIDES AND USE AS ANTICONVULSANTS. | YISSUM RES DEV CO (IL) | 1995-09-27 | — | — | EP | disclosed |
| EP-0659172-A1 | ANALOGUES OF VPA USED AS ANTI-EPILEPTICA. | NAU HEINZ (DE) | 1995-06-28 | — | — | EP | disclosed |
| EP-0659174-A1 | DERIVATIVES OF VALPROIC AND 2-VALPROENOIC ACID AMIDES AND USE AS ANTICONVULSANTS | YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM (IL) | 1995-06-28 | — | — | EP | disclosed |
| WO-1995001956-A1 | DERIVATIVES OF VALPROIC AND 2-VALPROENOIC ACID AMIDES AND USE AS ANTICONVULSANTS | YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM (IL) | 1995-01-19 | — | — | WO | disclosed |
| EP-0632008-A1 | Pentanoic acid derivatives | ONO PHARMACEUTICAL CO., LTD. (JP) | 1995-01-04 | — | — | EP | disclosed |
| WO-1994006743-A1 | ANALOGUES OF VPA USED AS ANTI-EPILEPTICA | NAU HEINZ (DE) | 1994-03-31 | — | — | WO | disclosed |
| US-5262561-A | Dehydrobromination of ester, saponification, antiepileptic agents | ELF SANOFI (FR) | 1993-11-16 | — | — | US | disclosed |
| US-5262561-A | Dehydrobromination of ester, saponification, antiepileptic agents | ELF SANOFI (FR) | 1993-11-16 | — | — | US | disclosed |
| US-5262561-A | Dehydrobromination of ester, saponification, antiepileptic agents | ELF SANOFI (FR) | 1993-11-16 | — | — | US | disclosed |
| JP-H05117204-A | (E)-2-PROPYL-2-PENTENOIC ACID | ELF SANOFI | 1993-05-14 | — | — | JP | disclosed |
| US-5162573-A | Anticonvulsant, antiepileptic agent | CHIESI FARMACEUTICI S.P.A. (IT) | 1992-11-10 | — | — | US | disclosed |
| US-5162573-A | Anticonvulsant, antiepileptic agent | CHIESI FARMACEUTICI S.P.A. (IT) | 1992-11-10 | — | — | US | disclosed |
| EP-0504069-A2 | Process for preparing E-2-propyl-2-pentenoic acid and intermediate products | ELF SANOFI (FR) | 1992-09-16 | — | — | EP | disclosed |
| EP-0250997-B1 | VALPROIC AND (E)-2-VALPROENOIC ACID DERIVATIVES, PROCESSES FOR THE PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITIONS THEREFROM | CHIESI FARMACEUTICI S.p.A. (IT) | 1992-04-15 | — | — | EP | disclosed |
| US-5101070-A | From an acetoacetic acid ester; by-product minimization | NIPPON GOHSEI KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1992-03-31 | — | — | US | disclosed |
| US-5101070-A | From an acetoacetic acid ester; by-product minimization | NIPPON GOHSEI KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1992-03-31 | — | — | US | disclosed |
| US-4966996-A | Process for the preparation of E-2-propyl-2-pentenoic acid and physiologically compatible salts thereof | Desitin Arznemittel GmbH (DE) | 1990-10-30 | — | — | US | disclosed |
| US-4966996-A | Process for the preparation of E-2-propyl-2-pentenoic acid and physiologically compatible salts thereof | Desitin Arznemittel GmbH (DE) | 1990-10-30 | — | — | US | disclosed |
| US-4966996-A | Process for the preparation of E-2-propyl-2-pentenoic acid and physiologically compatible salts thereof | Desitin Arznemittel GmbH (DE) | 1990-10-30 | — | — | US | disclosed |
| US-4965401-A | Process for the preparation of 2-propyl-2-pentenoic acid and its esters | SANOFI (FR) | 1990-10-23 | — | — | US | disclosed |
| US-4965401-A | Process for the preparation of 2-propyl-2-pentenoic acid and its esters | SANOFI (FR) | 1990-10-23 | — | — | US | disclosed |
| US-4945180-A | Process for the preparation of E-2-propyl-2-pentenoic acid and physiologically compatible salts thereof | DESITIN ARZNEIMITTEL GMBH (DE) | 1990-07-31 | — | — | US | disclosed |
| US-4945180-A | Process for the preparation of E-2-propyl-2-pentenoic acid and physiologically compatible salts thereof | DESITIN ARZNEIMITTEL GMBH (DE) | 1990-07-31 | — | — | US | disclosed |
| US-4945180-A | Process for the preparation of E-2-propyl-2-pentenoic acid and physiologically compatible salts thereof | DESITIN ARZNEIMITTEL GMBH (DE) | 1990-07-31 | — | — | US | disclosed |
| EP-0373057-A1 | Process for the preparation of (2-propyl)2-pentenoic acid and its esters | ELF SANOFI (FR) | 1990-06-13 | — | — | EP | disclosed |
| EP-0293753-A2 | Process for preparing E-2-propyl-2-pentenoic acid and its physiologically compatible salts | Desitin Arzneimittel GmbH (DE) | 1988-12-07 | — | — | EP | disclosed |
| EP-0293753-A2 | Process for preparing E-2-propyl-2-pentenoic acid and its physiologically compatible salts | Desitin Arzneimittel GmbH (DE) | 1988-12-07 | — | — | EP | disclosed |
| EP-0293752-A2 | Process for preparing E-2-propyl-2-pentenoic acid and its physiologically compatible salts | Desitin Arzneimittel GmbH (DE) | 1988-12-07 | — | — | EP | disclosed |
| EP-0293752-A2 | Process for preparing E-2-propyl-2-pentenoic acid and its physiologically compatible salts | Desitin Arzneimittel GmbH (DE) | 1988-12-07 | — | — | EP | disclosed |
| EP-0250997-A2 | Valproic and (E)-2-valproenoic acid derivatives, processes for the preparation thereof and pharmaceutical compositions therefrom | CHIESI FARMACEUTICI S.p.A. (IT) | 1988-01-07 | — | — | EP | disclosed |
| EP-0250997-A2 | Valproic and (E)-2-valproenoic acid derivatives, processes for the preparation thereof and pharmaceutical compositions therefrom | CHIESI FARMACEUTICI S.p.A. (IT) | 1988-01-07 | — | — | EP | disclosed |
| US-4432985-A | N-alkylated carboxylic acid derivatives as anti-convulsant agents | ABBOTT LABORATORIES (US) | 1984-02-21 | — | — | US | disclosed |
| EP-0024682-B1 | PROCESS FOR THE PREPARATION OF N-PROPYL-N-PROPYLIDENE ACETAMIDE OR DI-N-PROPYL ACETAMIDE | Consortium für elektrochemische Industrie GmbH (DE) | 1982-12-22 | — | — | EP | disclosed |
| EP-0024682-A1 | Process for the preparation of n-propyl-n-propylidene acetamide or di-n-propyl acetamide | Consortium für elektrochemische Industrie GmbH (DE) | 1981-03-11 | — | — | EP | disclosed |
| US-4082792-A | SECONDARY ALKYL PRIMARY AMINE, ALKENOIC ACID, PRIMARY OR SECONDARY ALCOHOL | TEXACO INC. (US) | 1978-04-04 | — | — | US | disclosed |
| US-3976682-A | ALKYLAMMONIUM ALKYLAMINOALKANOATES, FREEZE-THAW ADDITIVE, CORROSION INHIBITOR, PIGMENT GRINDING | TEXACO INC. (US) | 1976-08-24 | — | — | US | disclosed |
| US-3976682-A | ALKYLAMMONIUM ALKYLAMINOALKANOATES, FREEZE-THAW ADDITIVE, CORROSION INHIBITOR, PIGMENT GRINDING | TEXACO INC. (US) | 1976-08-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (19 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050267168-A1 | Pentanoic acid derivatives | FFAR3, FFAR1, HCAR3 | GRIK1 53/4885GRIK2 170/4885HDAC3 956/4885 |
| US-20070043114-A1 | Nerve regeneration promoters | BDNF, NGF, GAP43 | GRIK1 1591/4885GRIK2 1779/4885HDAC3 2611/4885 |
| US-20030096802-A1 | Pentanoic acid derivatives | FFAR3, FPR1, FPR3 | GRIK1 20/4885GRIK2 48/4885HDAC3 969/4885 |
| US-12246026-B2 | Ganaxolone for use in treatment of status epilepticus | CYP21A2, CYP17A1, HSD17B11 | GRIK1 49/4885GRIK2 44/4885HDAC3 349/4885 |
| US-20210186987-A1 | GANAXOLONE FOR USE IN TREATMENT OF STATUS EPILEPTICUS | CYP21A2, CYP17A1, HSD17B11 | GRIK1 49/4885GRIK2 44/4885HDAC3 349/4885 |
| US-20220265680-A1 | GANAXOLONE FOR USE IN TREATMENT OF STATUS EPILEPTICUS | CYP21A2, CYP17A1, HSD17B11 | GRIK1 49/4885GRIK2 44/4885HDAC3 349/4885 |
| US-20050267167-A1 | Pentanoic acid derivatives | FFAR3, FFAR1, HCAR3 | GRIK1 53/4885GRIK2 170/4885HDAC3 956/4885 |
| US-20050261371-A1 | Pentanoic acid derivatives | FFAR3, FFAR1, HCAR3 | GRIK1 54/4885GRIK2 169/4885HDAC3 905/4885 |
| US-11110100-B2 | Ganaxolone for use in treatment of status epilepticus | CYP21A2, CYP17A1, HSD17B11 | GRIK1 49/4885GRIK2 44/4885HDAC3 349/4885 |
| US-20130029924-A1 | GLYCOSYLATED VALPROIC ACID ANALOGS AND USES THEREOF | HDAC3, VGF, HDAC1 | GRIK1 147/4885GRIK2 81/4885HDAC3 1/4885 |
| US-20260021111-A1 | GANAXOLONE FOR USE IN TREATMENT OF STATUS EPILEPTICUS | CYP4A11, CYP21A2, CYP17A1 | GRIK1 151/4885GRIK2 131/4885HDAC3 1417/4885 |
| US-20150119346-A1 | GLYCOSYLATED VALPROIC ACID ANALOGS AND USES THEREOF | HDAC3, VGF, HDAC1 | GRIK1 147/4885GRIK2 81/4885HDAC3 1/4885 |
| US-11679117-B2 | Ganaxolone for use in treatment of status epilepticus | CYP21A2, CYP17A1, HSD17B11 | GRIK1 49/4885GRIK2 44/4885HDAC3 349/4885 |
| US-20220202831-A1 | GANAXOLONE FOR USE IN TREATMENT OF STATUS EPILEPTICUS | CYP21A2, CYP17A1, HSD17B11 | GRIK1 49/4885GRIK2 44/4885HDAC3 349/4885 |
| US-20260146159-A1 | Random Copolymer | APP, PRUNE1, PFN1 | GRIK1 1586/4885GRIK2 1336/4885HDAC3 4832/4885 |
| US-20230405021-A1 | GANAXOLONE FOR USE IN TREATMENT OF STATUS EPILEPTICUS | CYP21A2, CYP17A1, HSD17B11 | GRIK1 49/4885GRIK2 44/4885HDAC3 349/4885 |
| US-12552935-B2 | Polydisulfide polymer | APP, PFAS, TIMCC | GRIK1 1613/4885GRIK2 1356/4885HDAC3 4863/4885 |
| US-20060223888-A1 | Valproic acid analogues and pharmaceutical composition thereof | MALT1, HDAC11, GABRA6 | GRIK1 144/4885GRIK2 90/4885HDAC3 8/4885 |
| US-20110015267-A1 | METHODS FOR THE PREPARATION AND USE OF AQUEOUS SOLUTIONS OF MAGNESIUM VALPROATE HYDRATE AND L-CARNITINE | SLC25A20, CPT1A, CPT1B | GRIK1 850/4885GRIK2 923/4885HDAC3 50/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.